185 related articles for article (PubMed ID: 21549855)
1. Manifestation of Pig-a mutant bone marrow erythroids and peripheral blood erythrocytes in mice treated with N-ethyl-N-nitrosourea: direct sequencing of Pig-a cDNA from bone marrow cells negative for GPI-anchored protein expression.
Kimoto T; Suzuki K; Kobayashi XM; Dobrovolsky VN; Heflich RH; Miura D; Kasahara Y
Mutat Res; 2011 Jul; 723(1):36-42. PubMed ID: 21549855
[TBL] [Abstract][Full Text] [Related]
2. Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea.
Miura D; Dobrovolsky VN; Kimoto T; Kasahara Y; Heflich RH
Mutat Res; 2009; 677(1-2):86-92. PubMed ID: 19501187
[TBL] [Abstract][Full Text] [Related]
3. Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl-N-nitrosourea-treated fisher 344 rats.
Miura D; Shaddock JG; Mittelstaedt RA; Dobrovolsky VN; Kimoto T; Kasahara Y; Heflich RH
Environ Mol Mutagen; 2011 Jun; 52(5):419-23. PubMed ID: 21542029
[TBL] [Abstract][Full Text] [Related]
4. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat.
Miura D; Dobrovolsky VN; Kasahara Y; Katsuura Y; Heflich RH
Environ Mol Mutagen; 2008 Oct; 49(8):614-21. PubMed ID: 18626999
[TBL] [Abstract][Full Text] [Related]
5. Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays.
Horibata K; Ukai A; Kimoto T; Suzuki T; Kamoshita N; Masumura K; Nohmi T; Honma M
Environ Mol Mutagen; 2013 Dec; 54(9):747-54. PubMed ID: 24105957
[TBL] [Abstract][Full Text] [Related]
6. Analysis of mutation in the rat Pig-a assay: II. Studies with bone marrow granulocytes.
Dad A; Revollo JR; Petibone DM; Pearce MG; Heflich RH; Dobrovolsky VN
Environ Mol Mutagen; 2018 Oct; 59(8):733-741. PubMed ID: 30091248
[TBL] [Abstract][Full Text] [Related]
7. The frequency of Pig-a mutant red blood cells in rats exposed in utero to N-ethyl-N-nitrosourea.
Dobrovolsky VN; Heflich RH; Ferguson SA
Environ Mol Mutagen; 2012 Jul; 53(6):440-50. PubMed ID: 22730214
[TBL] [Abstract][Full Text] [Related]
8. Analysis of mutation in the rat Pig-a assay: I) studies with bone marrow erythroid cells.
Revollo JR; Pearce MG; Dad A; Petibone DM; Robison TW; Roberts D; Dobrovolsky VN
Environ Mol Mutagen; 2018 Oct; 59(8):722-732. PubMed ID: 30091272
[TBL] [Abstract][Full Text] [Related]
9. Time course of cII gene mutant manifestation in the liver, spleen, and bone marrow of N-ethyl-N-nitrosourea-treated Big Blue transgenic mice.
Wang J; Liu X; Heflich RH; Chen T
Toxicol Sci; 2004 Nov; 82(1):124-8. PubMed ID: 15282403
[TBL] [Abstract][Full Text] [Related]
10. The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment.
Dobrovolsky VN; Miura D; Heflich RH; Dertinger SD
Environ Mol Mutagen; 2010; 51(8-9):825-35. PubMed ID: 20857433
[TBL] [Abstract][Full Text] [Related]
11. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants.
Miura D; Dobrovolsky VN; Mittelstaedt RA; Kasahara Y; Katsuura Y; Heflich RH
Environ Mol Mutagen; 2008 Oct; 49(8):622-30. PubMed ID: 18626996
[TBL] [Abstract][Full Text] [Related]
12. In vivo mutation assay based on the endogenous Pig-a locus.
Bryce SM; Bemis JC; Dertinger SD
Environ Mol Mutagen; 2008 May; 49(4):256-64. PubMed ID: 18288722
[TBL] [Abstract][Full Text] [Related]
13. Applying the erythrocyte Pig-a assay concept to rat epididymal sperm for germ cell mutagenicity evaluation.
Ji Z; LeBaron MJ
Environ Mol Mutagen; 2017 Aug; 58(7):485-493. PubMed ID: 28714084
[TBL] [Abstract][Full Text] [Related]
14. Sequencing analysis of mutations induced by N-ethyl-N-nitrosourea at different sampling times in mouse bone marrow.
Wang J; Chen T
J Appl Toxicol; 2010 Mar; 30(2):133-41. PubMed ID: 19764070
[TBL] [Abstract][Full Text] [Related]
15. Further development of the rat Pig-a mutation assay: measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes.
Kimoto T; Chikura S; Suzuki K; Kobayashi Xm; Itano Y; Horibata K; Honma M; Dobrovolsky VN; Heflich RH; Miura D; Kasahara Y
Environ Mol Mutagen; 2011 Dec; 52(9):774-83. PubMed ID: 22167888
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of Macaca mulatta as a model for genotoxicity studies.
Dobrovolsky VN; Shaddock JG; Mittelstaedt RA; Manjanatha MG; Miura D; Uchikawa M; Mattison DR; Morris SM
Mutat Res; 2009 Feb; 673(1):21-8. PubMed ID: 19073277
[TBL] [Abstract][Full Text] [Related]
17. Mutant frequency and mutational spectra in the Tk and Hprt genes of N-ethyl-N-nitrosourea-treated mouse lymphoma cellsdagger.
Chen T; Harrington-Brock K; Moore MM
Environ Mol Mutagen; 2002; 39(4):296-305. PubMed ID: 12112381
[TBL] [Abstract][Full Text] [Related]
18. Flow cytometric detection of Pig-A mutant red blood cells using an erythroid-specific antibody: application of the method for evaluating the in vivo genotoxicity of methylphenidate in adolescent rats.
Dobrovolsky VN; Boctor SY; Twaddle NC; Doerge DR; Bishop ME; Manjanatha MG; Kimoto T; Miura D; Heflich RH; Ferguson SA
Environ Mol Mutagen; 2010 Mar; 51(2):138-45. PubMed ID: 19658152
[TBL] [Abstract][Full Text] [Related]
19. Manifestation and persistence of Pig-a mutant red blood cells in C57BL/6 mice following single and split doses of N-ethyl-N-nitrosourea.
Bhalli JA; Pearce MG; Dobrovolsky VN; Heflich RH
Environ Mol Mutagen; 2011 Dec; 52(9):766-773. PubMed ID: 22167887
[TBL] [Abstract][Full Text] [Related]
20. Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice.
Walker VE; Gorelick NJ; Andrews JL; Craft TR; deBoer JG; Glickman BW; Skopek TR
Cancer Res; 1996 Oct; 56(20):4654-61. PubMed ID: 8840980
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
