BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 21550385)

  • 21. Oxidative metabolism of koumine is mainly catalyzed by microsomal CYP3A4/3A5.
    Hu Y; Wang Z; Huang X; Xia B; Tang L; Zheng Z; Ye L
    Xenobiotica; 2017 Jul; 47(7):584-591. PubMed ID: 27499416
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine.
    Wang RW; Liu L; Cheng H
    Drug Metab Dispos; 1996 Jul; 24(7):786-91. PubMed ID: 8818577
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Study of in vitro metabolism of m-nisoldipine in human liver microsomes and recombinant cytochrome P450 enzymes by liquid chromatography-mass spectrometry.
    Yuan L; Jia P; Sun Y; Zhao C; Zhi X; Sheng N; Zhang L
    J Pharm Biomed Anal; 2014 Aug; 97():65-71. PubMed ID: 24816159
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.
    Rodrigues AD; Roberts EM; Mulford DJ; Yao Y; Ouellet D
    Drug Metab Dispos; 1997 May; 25(5):623-30. PubMed ID: 9152603
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM; Verhoeven CH; Shimada T; Back DJ
    J Pharmacol Exp Ther; 1998 Dec; 287(3):975-82. PubMed ID: 9864282
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.
    Ono S; Hatanaka T; Miyazawa S; Tsutsui M; Aoyama T; Gonzalez FJ; Satoh T
    Xenobiotica; 1996 Nov; 26(11):1155-66. PubMed ID: 8948091
    [TBL] [Abstract][Full Text] [Related]  

  • 27. New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, "LC-(High Resolution)-MSn" and "LC-(High Resolution)-MS/MS".
    A Michely JA; Manier SK; Caspar AT; Brandt SD; Wallach J; Maurer HH
    Curr Neuropharmacol; 2017; 15(5):692-712. PubMed ID: 27758707
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies.
    Schmider J; Greenblatt DJ; von Moltke LL; Harmatz JS; Duan SX; Karsov D; Shader RI
    Pharmacology; 1996 Feb; 52(2):125-34. PubMed ID: 8851634
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes.
    Hokkanen J; Tolonen A; Mattila S; Turpeinen M
    Eur J Pharm Sci; 2011 Feb; 42(3):273-84. PubMed ID: 21168483
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
    Yamazaki H; Shimada T
    Drug Metab Dispos; 1998 Nov; 26(11):1053-7. PubMed ID: 9806945
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human intestine and liver microsomal metabolic differences between C19-diester and monoester diterpenoid alkaloids from the roots of Aconitum carmichaelii Debx.
    Zhang M; Peng CS; Li XB
    Toxicol In Vitro; 2017 Dec; 45(Pt 3):318-333. PubMed ID: 28919359
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
    Yamazaki H; Inoue K; Shaw PM; Checovich WJ; Guengerich FP; Shimada T
    J Pharmacol Exp Ther; 1997 Nov; 283(2):434-42. PubMed ID: 9353355
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Comparative metabolism of tussilagone in rat and human liver microsomes using ultra-high-performance liquid chromatography coupled with high-resolution LTQ-Orbitrap mass spectrometry.
    Zhang XS; Ren W; Bian BL; Zhao HY; Wang S
    Rapid Commun Mass Spectrom; 2015 Sep; 29(18):1641-50. PubMed ID: 26467116
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cytochrome P450 3A-dependent metabolism of a potent and selective gamma-aminobutyric acid Aalpha2/3 receptor agonist in vitro: involvement of cytochrome P450 3A5 displaying biphasic kinetics.
    Ma B; Polsky-Fisher SL; Vickers S; Cui D; Rodrigues AD
    Drug Metab Dispos; 2007 Aug; 35(8):1301-7. PubMed ID: 17460031
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5.
    Ye L; Yang XS; Lu LL; Chen WY; Zeng S; Yan TM; Dong LN; Peng XJ; Shi J; Liu ZQ
    Evid Based Complement Alternat Med; 2013; 2013():941093. PubMed ID: 23864901
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
    Chang SY; Li W; Traeger SC; Wang B; Cui D; Zhang H; Wen B; Rodrigues AD
    Drug Metab Dispos; 2008 Dec; 36(12):2513-22. PubMed ID: 18787056
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The exposure of highly toxic aconitine does not significantly impact the activity and expression of cytochrome P450 3A in rats determined by a novel ultra performance liquid chromatography-tandem mass spectrometric method of a specific probe buspirone.
    Zhu L; Yang X; Zhou J; Tang L; Xia B; Hu M; Zhou F; Liu Z
    Food Chem Toxicol; 2013 Jan; 51():396-403. PubMed ID: 23085095
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of rutaecarpine.
    Lee SK; Lee JH; Yoo HH; Kim DH; Jahng Y; Jeong TC
    J Pharm Biomed Anal; 2006 Apr; 41(1):304-9. PubMed ID: 16318905
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.