BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 21551232)

  • 1. Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice.
    Krebs P; Crozat K; Popkin D; Oldstone MB; Beutler B
    Blood; 2011 Jun; 117(24):6582-8. PubMed ID: 21551232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis.
    Crozat K; Hoebe K; Ugolini S; Hong NA; Janssen E; Rutschmann S; Mudd S; Sovath S; Vivier E; Beutler B
    J Exp Med; 2007 Apr; 204(4):853-63. PubMed ID: 17420270
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis.
    Dettmer-Monaco V; Weißert K; Ammann S; Monaco G; Lei L; Gräßel L; Rhiel M; Rositzka J; Kaufmann MM; Geiger K; Andrieux G; Lao J; Thoulass G; Schell C; Boerries M; Illert AL; Cornu TI; Ehl S; Aichele P; Cathomen T
    J Allergy Clin Immunol; 2024 Jan; 153(1):243-255.e14. PubMed ID: 37595758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic Deficiency of Interferon-γ Reveals Interferon-γ-Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis.
    Burn TN; Weaver L; Rood JE; Chu N; Bodansky A; Kreiger PA; Behrens EM
    Arthritis Rheumatol; 2020 Feb; 72(2):335-347. PubMed ID: 31400073
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lentiviral Gene Therapy for Familial Hemophagocytic Lymphohistiocytosis Type 3, Caused by
    Takushi SE; Paik NY; Fedanov A; Prince C; Doering CB; Spencer HT; Chandrakasan S
    Hum Gene Ther; 2020 Jun; 31(11-12):626-638. PubMed ID: 32253931
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice.
    Rood JE; Rao S; Paessler M; Kreiger PA; Chu N; Stelekati E; Wherry EJ; Behrens EM
    Blood; 2016 Jan; 127(4):426-35. PubMed ID: 26518437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UNC13D is the predominant causative gene with recurrent splicing mutations in Korean patients with familial hemophagocytic lymphohistiocytosis.
    Yoon HS; Kim HJ; Yoo KH; Sung KW; Koo HH; Kang HJ; Shin HY; Ahn HS; Kim JY; Lim YT; Bae KW; Lee KO; Shin JS; Lee ST; Chung HS; Kim SH; Park CJ; Chi HS; Im HJ; Seo JJ
    Haematologica; 2010 Apr; 95(4):622-6. PubMed ID: 20015888
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis.
    Brisse E; Imbrechts M; Put K; Avau A; Mitera T; Berghmans N; Rutgeerts O; Waer M; Ninivaggi M; Kelchtermans H; Boon L; Snoeck R; Wouters CH; Andrei G; Matthys P
    J Immunol; 2016 Apr; 196(7):3124-34. PubMed ID: 26903481
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases.
    Rohr J; Beutel K; Maul-Pavicic A; Vraetz T; Thiel J; Warnatz K; Bondzio I; Gross-Wieltsch U; Schündeln M; Schütz B; Woessmann W; Groll AH; Strahm B; Pagel J; Speckmann C; Janka G; Griffiths G; Schwarz K; zur Stadt U; Ehl S
    Haematologica; 2010 Dec; 95(12):2080-7. PubMed ID: 20823128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Primary hemophagocytic lymphohistiocytosis in adults: the utility of family surveys in a single-center study from China.
    Jin Z; Wang Y; Wang J; Zhang J; Wu L; Gao Z; Lai W; Wang Z
    Orphanet J Rare Dis; 2018 Jan; 13(1):17. PubMed ID: 29357941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retroviral
    Dettmer V; Bloom K; Gross M; Weissert K; Aichele P; Ehl S; Cathomen T
    Hum Gene Ther; 2019 Aug; 30(8):975-984. PubMed ID: 31032638
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IL-2 consumption by highly activated CD8 T cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis.
    Humblet-Baron S; Franckaert D; Dooley J; Bornschein S; Cauwe B; Schönefeldt S; Bossuyt X; Matthys P; Baron F; Wouters C; Liston A
    J Allergy Clin Immunol; 2016 Jul; 138(1):200-209.e8. PubMed ID: 26947179
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IFN-γ and CD25 drive distinct pathologic features during hemophagocytic lymphohistiocytosis.
    Humblet-Baron S; Franckaert D; Dooley J; Ailal F; Bousfiha A; Deswarte C; Oleaga-Quintas C; Casanova JL; Bustamante J; Liston A
    J Allergy Clin Immunol; 2019 Jun; 143(6):2215-2226.e7. PubMed ID: 30578871
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic variant spectrum in 265 Chinese patients with hemophagocytic lymphohistiocytosis: Molecular analyses of PRF1, UNC13D, STX11, STXBP2, SH2D1A, and XIAP.
    Chen X; Wang F; Zhang Y; Teng W; Wang M; Nie D; Zhou X; Wang D; Zhao H; Zhu P; Liu H
    Clin Genet; 2018 Aug; 94(2):200-212. PubMed ID: 29665027
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel mutations in the UNC13D gene carried by a Chinese neonate with hemophagocytic lymphohistiocytosis.
    Chen Y; Wang Z; Cheng Y; Tang Y
    Yonsei Med J; 2013 Jul; 54(4):1053-7. PubMed ID: 23709445
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Postoperative ileus involves interleukin-1 receptor signaling in enteric glia.
    Stoffels B; Hupa KJ; Snoek SA; van Bree S; Stein K; Schwandt T; Vilz TO; Lysson M; Veer CV; Kummer MP; Hornung V; Kalff JC; de Jonge WJ; Wehner S
    Gastroenterology; 2014 Jan; 146(1):176-87.e1. PubMed ID: 24067878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis.
    Huang R; Hayashi Y; Yan X; Bu J; Wang J; Zhang Y; Zhou Y; Tang Y; Wu L; Xu Z; Liu X; Wang Q; Zhou J; Xiao Z; Bridges JP; Marsh RA; Zhang K; Jordan MB; Li Y; Huang G
    Haematologica; 2017 Nov; 102(11):1956-1968. PubMed ID: 28860338
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a novel splicing mutation in UNC13D gene through amplicon sequencing: a case report on HLH.
    Liu D; Hu X; Jiang X; Gao B; Wan C; Chen C
    BMC Med Genet; 2017 Nov; 18(1):135. PubMed ID: 29157204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH).
    Weißert K; Ammann S; Kögl T; Dettmer-Monaco V; Schell C; Cathomen T; Ehl S; Aichele P
    EMBO Mol Med; 2022 Dec; 14(12):e16085. PubMed ID: 36278424
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.
    Zhizhuo H; Junmei X; Yuelin S; Qiang Q; Chunyan L; Zhengde X; Kunling S
    Pediatr Blood Cancer; 2012 Mar; 58(3):410-4. PubMed ID: 21674762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.