BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

353 related articles for article (PubMed ID: 21553932)

  • 1. Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on 4-anilinoquinazolines.
    Scheffler M; Di Gion P; Doroshyenko O; Wolf J; Fuhr U
    Clin Pharmacokinet; 2011 Jun; 50(6):371-403. PubMed ID: 21553932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clinical pharmacokinetics of tyrosine kinase inhibitors.
    van Erp NP; Gelderblom H; Guchelaar HJ
    Cancer Treat Rev; 2009 Dec; 35(8):692-706. PubMed ID: 19733976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on pyrimidines, pyridines and pyrroles.
    Di Gion P; Kanefendt F; Lindauer A; Scheffler M; Doroshyenko O; Fuhr U; Wolf J; Jaehde U
    Clin Pharmacokinet; 2011 Sep; 50(9):551-603. PubMed ID: 21827214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Clinical pharmacokinetics of small molecule tyrosine kinase inhibitors].
    Ding JF; Zhong DF
    Yao Xue Xue Bao; 2013 Jul; 48(7):1080-90. PubMed ID: 24133973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes.
    Li J; Zhao M; He P; Hidalgo M; Baker SD
    Clin Cancer Res; 2007 Jun; 13(12):3731-7. PubMed ID: 17575239
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacokinetic drug interactions of gefitinib with rifampicin, itraconazole and metoprolol.
    Swaisland HC; Ranson M; Smith RP; Leadbetter J; Laight A; McKillop D; Wild MJ
    Clin Pharmacokinet; 2005; 44(10):1067-81. PubMed ID: 16176119
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients.
    Li J; Cusatis G; Brahmer J; Sparreboom A; Robey RW; Bates SE; Hidalgo M; Baker SD
    Cancer Biol Ther; 2007 Mar; 6(3):432-8. PubMed ID: 17312388
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.
    Collins DM; Crown J; O'Donovan N; Devery A; O'Sullivan F; O'Driscoll L; Clynes M; O'Connor R
    Invest New Drugs; 2010 Aug; 28(4):433-44. PubMed ID: 19499189
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combining Nonclinical Experiments with Translational PKPD Modeling to Differentiate Erlotinib and Gefitinib.
    Eigenmann MJ; Frances N; Hoffmann G; Lavé T; Walz AC
    Mol Cancer Ther; 2016 Dec; 15(12):3110-3119. PubMed ID: 27638857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosine Kinase Inhibitors Imatinib and Erlotinib Increase Apoptosis of Antimitotic Drug-resistant KBV20C Cells Without Inhibiting P-gp.
    Kim JY; Kim HS; Yoon S
    Anticancer Res; 2019 Jul; 39(7):3785-3793. PubMed ID: 31262905
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [
    Traxl A; Mairinger S; Filip T; Sauberer M; Stanek J; Poschner S; Jäger W; Zoufal V; Novarino G; Tournier N; Bauer M; Wanek T; Langer O
    Mol Pharm; 2019 Mar; 16(3):1282-1293. PubMed ID: 30694684
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics of Gefitinib: Roles of Drug Metabolizing Enzymes and Transporters.
    Zhao C; Han SY; Li PP
    Curr Drug Deliv; 2017; 14(2):282-288. PubMed ID: 27396387
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of pharmacokinetics and pharmacogenomics with safety and efficacy of gefitinib in patients with EGFR mutation positive advanced non-small cell lung cancer.
    Hirose T; Fujita K; Kusumoto S; Oki Y; Murata Y; Sugiyama T; Ishida H; Shirai T; Nakashima M; Yamaoka T; Okuda K; Ohmori T; Sasaki Y
    Lung Cancer; 2016 Mar; 93():69-76. PubMed ID: 26898617
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes.
    Han SY; Zhao HY; Zhou N; Zhou F; Li PP
    J Ethnopharmacol; 2014; 151(1):210-7. PubMed ID: 24157377
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib.
    Deeken JF; Beumer JH; Anders NM; Wanjiku T; Rusnak M; Rudek MA
    Cancer Chemother Pharmacol; 2015 Oct; 76(4):813-9. PubMed ID: 26330331
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Use of a physiologically based pharmacokinetic model to simulate drug-drug interactions between antineoplastic and antiretroviral drugs.
    Moltó J; Rajoli R; Back D; Valle M; Miranda C; Owen A; Clotet B; Siccardi M
    J Antimicrob Chemother; 2017 Mar; 72(3):805-811. PubMed ID: 27999009
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clinical pharmacokinetics and pharmacodynamics of linagliptin.
    Graefe-Mody U; Retlich S; Friedrich C
    Clin Pharmacokinet; 2012 Jul; 51(7):411-27. PubMed ID: 22568694
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Changes in gefitinib, erlotinib and osimertinib pharmacokinetics under various gastric pH levels following oral administration of omeprazole and vonoprazan in rats.
    Yasumuro O; Uchida S; Kashiwagura Y; Suzuki A; Tanaka S; Inui N; Watanabe H; Namiki N
    Xenobiotica; 2018 Nov; 48(11):1106-1112. PubMed ID: 29057719
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity.
    Rudin CM; Liu W; Desai A; Karrison T; Jiang X; Janisch L; Das S; Ramirez J; Poonkuzhali B; Schuetz E; Fackenthal DL; Chen P; Armstrong DK; Brahmer JR; Fleming GF; Vokes EE; Carducci MA; Ratain MJ
    J Clin Oncol; 2008 Mar; 26(7):1119-27. PubMed ID: 18309947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exploring the relationship between expression of cytochrome P450 enzymes and gefitinib pharmacokinetics.
    Swaisland HC; Cantarini MV; Fuhr R; Holt A
    Clin Pharmacokinet; 2006; 45(6):633-44. PubMed ID: 16719544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.