BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 21554732)

  • 1. Expression of mutant alpha-synuclein modulates microglial phenotype in vitro.
    Rojanathammanee L; Murphy EJ; Combs CK
    J Neuroinflammation; 2011 May; 8():44. PubMed ID: 21554732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant.
    Hoenen C; Gustin A; Birck C; Kirchmeyer M; Beaume N; Felten P; Grandbarbe L; Heuschling P; Heurtaux T
    PLoS One; 2016; 11(9):e0162717. PubMed ID: 27622765
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alpha-synuclein expression modulates microglial activation phenotype.
    Austin SA; Floden AM; Murphy EJ; Combs CK
    J Neurosci; 2006 Oct; 26(41):10558-63. PubMed ID: 17035541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Parkinson's disease-derived α-synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype.
    Yildirim-Balatan C; Fenyi A; Besnault P; Gomez L; Sepulveda-Diaz JE; Michel PP; Melki R; Hunot S
    J Neuroinflammation; 2024 Feb; 21(1):54. PubMed ID: 38383421
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition.
    Wu KC; Liou HH; Kao YH; Lee CY; Lin CJ
    Neurobiol Dis; 2017 Aug; 104():61-72. PubMed ID: 28476637
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pathological α-synuclein exacerbates the progression of Parkinson's disease through microglial activation.
    Zhang QS; Heng Y; Yuan YH; Chen NH
    Toxicol Lett; 2017 Jan; 265():30-37. PubMed ID: 27865851
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alpha-synuclein activates BV2 microglia dependent on its aggregation state.
    Hoffmann A; Ettle B; Bruno A; Kulinich A; Hoffmann AC; von Wittgenstein J; Winkler J; Xiang W; Schlachetzki JCM
    Biochem Biophys Res Commun; 2016 Oct; 479(4):881-886. PubMed ID: 27666480
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of Galectin-3 in α-synuclein-induced microglial activation.
    Boza-Serrano A; Reyes JF; Rey NL; Leffler H; Bousset L; Nilsson U; Brundin P; Venero JL; Burguillos MA; Deierborg T
    Acta Neuropathol Commun; 2014 Nov; 2():156. PubMed ID: 25387690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.
    Zhang W; Wang T; Pei Z; Miller DS; Wu X; Block ML; Wilson B; Zhang W; Zhou Y; Hong JS; Zhang J
    FASEB J; 2005 Apr; 19(6):533-42. PubMed ID: 15791003
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabotropic glutamate receptor 5 inhibits α-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson's disease.
    Zhang YN; Fan JK; Gu L; Yang HM; Zhan SQ; Zhang H
    J Neuroinflammation; 2021 Jan; 18(1):23. PubMed ID: 33461598
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.
    Gu XL; Long CX; Sun L; Xie C; Lin X; Cai H
    Mol Brain; 2010 Apr; 3():12. PubMed ID: 20409326
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of alpha-synuclein modulates microglial phenotype in vitro.
    Austin SA; Rojanathammanee L; Golovko MY; Murphy EJ; Combs CK
    Neurochem Res; 2011 Jun; 36(6):994-1004. PubMed ID: 21384098
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Plasma exosomes impair microglial degradation of α-synuclein through V-ATPase subunit V1G1.
    Li Y; Wang Y; Kou L; Yin S; Chi X; Sun Y; Wu J; Jin Z; Zhou Q; Zou W; Wang T; Xia Y
    CNS Neurosci Ther; 2024 May; 30(5):e14738. PubMed ID: 38702933
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.
    Fellner L; Irschick R; Schanda K; Reindl M; Klimaschewski L; Poewe W; Wenning GK; Stefanova N
    Glia; 2013 Mar; 61(3):349-60. PubMed ID: 23108585
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein.
    Zhang W; Dallas S; Zhang D; Guo JP; Pang H; Wilson B; Miller DS; Chen B; Zhang W; McGeer PL; Hong JS; Zhang J
    Glia; 2007 Aug; 55(11):1178-88. PubMed ID: 17600340
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
    Xia Y; Zhang G; Kou L; Yin S; Han C; Hu J; Wan F; Sun Y; Wu J; Li Y; Huang J; Xiong N; Zhang Z; Wang T
    Brain; 2021 Aug; 144(7):2024-2037. PubMed ID: 33792662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reactive macrophages increase oxidative stress and alpha-synuclein nitration during death of dopaminergic neuronal cells in co-culture: relevance to Parkinson's disease.
    Shavali S; Combs CK; Ebadi M
    Neurochem Res; 2006 Jan; 31(1):85-94. PubMed ID: 16475001
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.
    Reynolds AD; Glanzer JG; Kadiu I; Ricardo-Dukelow M; Chaudhuri A; Ciborowski P; Cerny R; Gelman B; Thomas MP; Mosley RL; Gendelman HE
    J Neurochem; 2008 Mar; 104(6):1504-25. PubMed ID: 18036154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Microglial LRRK2-mediated NFATc1 attenuates α-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation.
    Feng L; Lo H; Hong Z; Zheng J; Yan Y; Ye Z; Chen X; Pan X
    Glia; 2023 Sep; 71(9):2266-2284. PubMed ID: 37300531
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of α-synuclein in microglia: autophagy and phagocytosis balance neuroinflammation in Parkinson's disease.
    Lv QK; Tao KX; Wang XB; Yao XY; Pang MZ; Liu JY; Wang F; Liu CF
    Inflamm Res; 2023 Mar; 72(3):443-462. PubMed ID: 36598534
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.