242 related articles for article (PubMed ID: 21561529)
1. Calpain regulates thymidylate synthase-5-fluoro-dUMP complex levels associated with response to 5-fluorouracil in gastric cancer cells.
Nabeya Y; Suzuki T; Furuya A; Koide N; Ohkoshi M; Takiguchi M; Ochiai T; Matsubara H; Hiwasa T
Cancer Sci; 2011 Aug; 102(8):1509-15. PubMed ID: 21561529
[TBL] [Abstract][Full Text] [Related]
2. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
3. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines.
Johnston PG; Drake JC; Trepel J; Allegra CJ
Cancer Res; 1992 Aug; 52(16):4306-12. PubMed ID: 1643628
[TBL] [Abstract][Full Text] [Related]
4. Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil.
Spears CP; Gustavsson BG; Berne M; Frösing R; Bernstein L; Hayes AA
Cancer Res; 1988 Oct; 48(20):5894-900. PubMed ID: 3167844
[TBL] [Abstract][Full Text] [Related]
5. Apoptosis and thymidylate synthase inductions by 5-fluorouracil in gastric cancer cells with or without p53 mutation.
Yukimoto K; Nakata B; Muguruma K; Yashiro M; Ohira M; Ishikawa T; Hino M; Hirakawa K
Int J Oncol; 2001 Aug; 19(2):373-8. PubMed ID: 11445854
[TBL] [Abstract][Full Text] [Related]
6. [5-FU sensitivity and thymidylate synthase in gastric cancer].
Suda Y; Uchida K; Shioya T; Tanaka Y; Kuwashima Y; Yano T
Gan To Kagaku Ryoho; 1999 Dec; 26(14):2169-73. PubMed ID: 10635300
[TBL] [Abstract][Full Text] [Related]
7. Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines.
McGinn CJ; Pestalozzi BC; Drake JC; Glennon MC; Kunugi K; Otterson G; Allegra CJ; Johnston PG; Kinsella TJ
Cancer J; 2000; 6(4):234-42. PubMed ID: 11038143
[TBL] [Abstract][Full Text] [Related]
8. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
Spears CP; Shahinian AH; Moran RG; Heidelberger C; Corbett TH
Cancer Res; 1982 Feb; 42(2):450-6. PubMed ID: 6173112
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks.
Wang W; McLeod HL; Cassidy J; Collie-Duguid ES
Cancer Chemother Pharmacol; 2007 May; 59(6):839-45. PubMed ID: 17119966
[TBL] [Abstract][Full Text] [Related]
10. Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion.
Myers CE; Young RC; Chabner BA
J Clin Invest; 1975 Nov; 56(5):1231-8. PubMed ID: 1184747
[TBL] [Abstract][Full Text] [Related]
11. Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines.
Chu E; Drake JC; Koeller DM; Zinn S; Jamis-Dow CA; Yeh GC; Allegra CJ
Mol Pharmacol; 1991 Feb; 39(2):136-43. PubMed ID: 1704999
[TBL] [Abstract][Full Text] [Related]
12. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
[TBL] [Abstract][Full Text] [Related]
13. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
[TBL] [Abstract][Full Text] [Related]
14. [The correlation between thymidylate synthase expression and cytotoxicity of 5-fluorouracil in human cancer cell lines: study using polyclonal antibody against recombinant human thymidylate synthase].
Okabe H; Tsujimoto H; Fukushima M
Gan To Kagaku Ryoho; 1997 Apr; 24(6):705-12. PubMed ID: 9126308
[TBL] [Abstract][Full Text] [Related]
15. Sequential methotrexate and 5-fluorouracil: mechanisms of synergy.
Bertino JR; Mini E; Fernandes DJ
Semin Oncol; 1983 Jun; 10(2 Suppl 2):2-5. PubMed ID: 6867754
[TBL] [Abstract][Full Text] [Related]
16. Reduction of 5-fluorouracil (5-FU) gastrointestinal (GI) toxicity resulting from the protection of thymidylate synthase (TS) in GI tissue by repeated simultaneous administration of potassium oxonate (Oxo) in rats.
Yoshisue K; Hironaga K; Yamaguchi S; Yamamoto A; Nagayama S; Kawaguchi Y
Cancer Chemother Pharmacol; 2000; 46(1):51-6. PubMed ID: 10912578
[TBL] [Abstract][Full Text] [Related]
17. Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil.
Yeh KH; Yeh SH; Hsu CH; Wang TM; Ma IF; Cheng AL
Br J Cancer; 2000 Dec; 83(11):1510-5. PubMed ID: 11076661
[TBL] [Abstract][Full Text] [Related]
18. Roles of thymidylate synthase and dihydropyrimidine dehydrogenase in tumor progression and sensitivity to 5-fluorouracil in human gastric cancer.
Terashima M; Irinoda T; Fujiwara H; Nakaya T; Takagane A; Abe K; Yonezawa H; Oyama K; Inaba T; Saito K; Takechi T; Fukushima M
Anticancer Res; 2002; 22(2A):761-8. PubMed ID: 12014648
[TBL] [Abstract][Full Text] [Related]
19. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.
Grem JL; Danenberg KD; Behan K; Parr A; Young L; Danenberg PV; Nguyen D; Drake J; Monks A; Allegra CJ
Clin Cancer Res; 2001 Apr; 7(4):999-1009. PubMed ID: 11309351
[TBL] [Abstract][Full Text] [Related]
20. UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner.
Hsueh CT; Kelsen D; Schwartz GK
Clin Cancer Res; 1998 Sep; 4(9):2201-6. PubMed ID: 9748140
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]