BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 21561860)

  • 1. Bim protein degradation contributes to cisplatin resistance.
    Wang J; Zhou JY; Wu GS
    J Biol Chem; 2011 Jun; 286(25):22384-92. PubMed ID: 21561860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Up-regulation of pro-apoptotic protein Bim and down-regulation of anti-apoptotic protein Mcl-1 cooperatively mediate enhanced tumor cell death induced by the combination of ERK kinase (MEK) inhibitor and microtubule inhibitor.
    Kawabata T; Tanimura S; Asai K; Kawasaki R; Matsumaru Y; Kohno M
    J Biol Chem; 2012 Mar; 287(13):10289-10300. PubMed ID: 22270368
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells.
    Abutin RM; Chen J; Lung TK; Lloyd JA; Sawyer ST; Harada H
    Exp Hematol; 2009 Feb; 37(2):151-8. PubMed ID: 19100675
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.
    Yuan Z; Wang F; Zhao Z; Zhao X; Qiu J; Nie C; Wei Y
    PLoS One; 2011; 6(5):e20586. PubMed ID: 21655183
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death.
    Li Z; Zhang J; Liu Z; Woo CW; Thiele CJ
    Cell Death Differ; 2007 Feb; 14(2):318-26. PubMed ID: 16778834
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beta1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells.
    Hazlehurst LA; Argilagos RF; Dalton WS
    Br J Haematol; 2007 Jan; 136(2):269-75. PubMed ID: 17233818
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.
    Park SH; Ito K; Olcott W; Katsyv I; Halstead-Nussloch G; Irie HY
    Breast Cancer Res; 2015 Jun; 17(1):86. PubMed ID: 26084280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.
    Zaanan A; Okamoto K; Kawakami H; Khazaie K; Huang S; Sinicrope FA
    J Biol Chem; 2015 Sep; 290(39):23838-49. PubMed ID: 26245900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.
    Nalluri S; Peirce SK; Tanos R; Abdella HA; Karmali D; Hogarty MD; Goldsmith KC
    Cancer Biol Ther; 2015; 16(2):276-86. PubMed ID: 25756510
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1.
    Yuan Z; Cao K; Lin C; Li L; Liu HY; Zhao XY; Liu L; Deng HX; Li J; Nie CL; Wei YQ
    Mol Med; 2011; 17(11-12):1262-74. PubMed ID: 21863213
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma.
    Kong LR; Chua KN; Sim WJ; Ng HC; Bi C; Ho J; Nga ME; Pang YH; Ong WR; Soo RA; Huynh H; Chng WJ; Thiery JP; Goh BC
    Mol Cancer Ther; 2015 Jul; 14(7):1750-60. PubMed ID: 25939760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism.
    Pei XY; Dai Y; Tenorio S; Lu J; Harada H; Dent P; Grant S
    Blood; 2007 Sep; 110(6):2092-101. PubMed ID: 17540843
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons.
    Meller R; Cameron JA; Torrey DJ; Clayton CE; Ordonez AN; Henshall DC; Minami M; Schindler CK; Saugstad JA; Simon RP
    J Biol Chem; 2006 Mar; 281(11):7429-36. PubMed ID: 16431916
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MAPK pathway activation leads to Bim loss and histone deacetylase inhibitor resistance: rationale to combine romidepsin with an MEK inhibitor.
    Chakraborty AR; Robey RW; Luchenko VL; Zhan Z; Piekarz RL; Gillet JP; Kossenkov AV; Wilkerson J; Showe LC; Gottesman MM; Collie NL; Bates SE
    Blood; 2013 May; 121(20):4115-25. PubMed ID: 23532732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells.
    Wang J; Zhou JY; Zhang L; Wu GS
    Cell Cycle; 2009 Oct; 8(19):3191-8. PubMed ID: 19755862
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells.
    Li C; Li R; Grandis JR; Johnson DE
    Mol Cancer Ther; 2008 Jun; 7(6):1647-55. PubMed ID: 18566236
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells.
    Chen K; Tu Y; Zhang Y; Blair HC; Zhang L; Wu C
    J Biol Chem; 2008 Feb; 283(5):2508-17. PubMed ID: 18063582
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer.
    Li Z; Zhou S; Zhang L; Su C; Hang J; Zhao Y; Su B; Zhou C
    Med Oncol; 2011 Jun; 28(2):572-7. PubMed ID: 20237869
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms.
    Paraiso KH; Haarberg HE; Wood E; Rebecca VW; Chen YA; Xiang Y; Ribas A; Lo RS; Weber JS; Sondak VK; John JK; Sarnaik AA; Koomen JM; Smalley KS
    Clin Cancer Res; 2012 May; 18(9):2502-14. PubMed ID: 22351686
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.