These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 21561860)

  • 21. FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors.
    Kiyota M; Kuroda J; Yamamoto-Sugitani M; Shimura Y; Nakayama R; Nagoshi H; Mizutani S; Chinen Y; Sasaki N; Sakamoto N; Kobayashi T; Matsumoto Y; Horiike S; Taniwaki M
    Apoptosis; 2013 Nov; 18(11):1437-1446. PubMed ID: 23851982
    [TBL] [Abstract][Full Text] [Related]  

  • 22. PI3K/mTOR dual inhibitor NVP-BEZ235 decreases Mcl-1 expression and sensitizes ovarian carcinoma cells to Bcl-xL-targeting strategies, provided that Bim expression is induced.
    Jebahi A; Villedieu M; Pétigny-Lechartier C; Brotin E; Louis MH; Abeilard E; Giffard F; Guercio M; Briand M; Gauduchon P; Lheureux S; Poulain L
    Cancer Lett; 2014 Jun; 348(1-2):38-49. PubMed ID: 24650799
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.
    Sheridan C; Brumatti G; Martin SJ
    J Biol Chem; 2008 Aug; 283(32):22128-35. PubMed ID: 18508762
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim.
    Howie HL; Shiflett SL; So M
    Infect Immun; 2008 Jun; 76(6):2715-21. PubMed ID: 18391004
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis.
    Whelan KA; Caldwell SA; Shahriari KS; Jackson SR; Franchetti LD; Johannes GJ; Reginato MJ
    Mol Biol Cell; 2010 Nov; 21(22):3829-37. PubMed ID: 20861305
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.
    Stang SL; Lopez-Campistrous A; Song X; Dower NA; Blumberg PM; Wender PA; Stone JC
    Exp Hematol; 2009 Jan; 37(1):122-134. PubMed ID: 19100522
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.
    Chetoui N; Sylla K; Gagnon-Houde JV; Alcaide-Loridan C; Charron D; Al-Daccak R; Aoudjit F
    Mol Cancer Res; 2008 Jan; 6(1):42-52. PubMed ID: 18234961
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The increase in BIK expression following ERK1/2 pathway inhibition is a consequence of G₁ cell-cycle arrest and not a direct effect on BIK protein stability.
    Sale MJ; Cook SJ
    Biochem J; 2014 May; 459(3):513-24. PubMed ID: 24527759
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Tubeimoside I sensitizes cisplatin in cisplatin-resistant human ovarian cancer cells (A2780/DDP) through down-regulation of ERK and up-regulation of p38 signaling pathways.
    Liu HZ; Yu C; Yang Z; He JL; Chen WJ; Yin J; Li WM; Liu HT; Wang YX
    Mol Med Rep; 2011; 4(5):985-92. PubMed ID: 21687949
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Histone demethylase Jmjd3 regulates osteoblast apoptosis through targeting anti-apoptotic protein Bcl-2 and pro-apoptotic protein Bim.
    Yang D; Okamura H; Teramachi J; Haneji T
    Biochim Biophys Acta; 2016 Apr; 1863(4):650-9. PubMed ID: 26795455
    [TBL] [Abstract][Full Text] [Related]  

  • 31. MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation.
    O'Reilly LA; Kruse EA; Puthalakath H; Kelly PN; Kaufmann T; Huang DC; Strasser A
    J Immunol; 2009 Jul; 183(1):261-9. PubMed ID: 19542438
    [TBL] [Abstract][Full Text] [Related]  

  • 32. [Chemotherapy resistance induced by interleukin-6 in ovarian cancer cells and its signal transduction pathways].
    Wang Y; Li LZ; Ye L; Niu XL; Liu X; Zhu YQ; Sun WJ; Liang YJ
    Zhonghua Fu Chan Ke Za Zhi; 2010 Sep; 45(9):691-8. PubMed ID: 21092551
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin.
    Hayakawa J; Ohmichi M; Kurachi H; Kanda Y; Hisamoto K; Nishio Y; Adachi K; Tasaka K; Kanzaki T; Murata Y
    Cancer Res; 2000 Nov; 60(21):5988-94. PubMed ID: 11085518
    [TBL] [Abstract][Full Text] [Related]  

  • 34. BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway.
    Craxton A; Draves KE; Gruppi A; Clark EA
    J Exp Med; 2005 Nov; 202(10):1363-74. PubMed ID: 16301744
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role for the proapoptotic factor BIM in mediating imatinib-induced apoptosis in a c-KIT-dependent gastrointestinal stromal tumor cell line.
    Gordon PM; Fisher DE
    J Biol Chem; 2010 May; 285(19):14109-14. PubMed ID: 20231287
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin.
    Dhar R; Basu A
    Int J Oncol; 2008 May; 32(5):1133-7. PubMed ID: 18425342
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Phosphorylation and down-regulation of Bim by muscarinic cholinergic receptor activation via protein kinase C.
    Styles NA; Zhu W; Li X
    Neurochem Int; 2005 Dec; 47(8):519-27. PubMed ID: 16183168
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF; Jiang CC; Kiejda KA; Gillespie S; Zhang XD; Hersey P
    Clin Cancer Res; 2007 Aug; 13(16):4934-42. PubMed ID: 17652623
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor CI-1040 in hepatocellular carcinoma.
    Ou DL; Shen YC; Liang JD; Liou JY; Yu SL; Fan HH; Wang DS; Lu YS; Hsu C; Cheng AL
    Clin Cancer Res; 2009 Sep; 15(18):5820-8. PubMed ID: 19737956
    [TBL] [Abstract][Full Text] [Related]  

  • 40. EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities.
    Quadros MR; Connelly S; Kari C; Abrams MT; Wickstrom E; Rodeck U
    Cancer Biol Ther; 2006 May; 5(5):498-504. PubMed ID: 16582597
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.