These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 21563224)

  • 21. Quantitative analysis of the relative contributions of donor acyl carrier proteins, acceptor ketosynthases, and linker regions to intermodular transfer of intermediates in hybrid polyketide synthases.
    Wu N; Cane DE; Khosla C
    Biochemistry; 2002 Apr; 41(15):5056-66. PubMed ID: 11939803
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.
    Weissman KJ; Hong H; Popovic B; Meersman F
    Chem Biol; 2006 Jun; 13(6):625-36. PubMed ID: 16793520
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structure and mechanism of assembly line polyketide synthases.
    Robbins T; Liu YC; Cane DE; Khosla C
    Curr Opin Struct Biol; 2016 Dec; 41():10-18. PubMed ID: 27266330
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Ketosynthase Domain Constrains the Design of Polyketide Synthases.
    Klaus M; Buyachuihan L; Grininger M
    ACS Chem Biol; 2020 Sep; 15(9):2422-2432. PubMed ID: 32786257
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.
    Feng Y; Zhang F; Huang S; Deng Z; Bai L; Zheng J
    Acta Crystallogr D Struct Biol; 2022 Jun; 78(Pt 6):779-791. PubMed ID: 35647924
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.
    Tang Y; Kim CY; Mathews II; Cane DE; Khosla C
    Proc Natl Acad Sci U S A; 2006 Jul; 103(30):11124-9. PubMed ID: 16844787
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Type I polyketide synthases that require discrete acyltransferases.
    Cheng YQ; Coughlin JM; Lim SK; Shen B
    Methods Enzymol; 2009; 459():165-86. PubMed ID: 19362640
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.
    Bruegger J; Haushalter RW; Vagstad AL; Shakya G; Mih N; Townsend CA; Burkart MD; Tsai SC
    Chem Biol; 2013 Sep; 20(9):1135-46. PubMed ID: 23993461
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Covalent linkage mediates communication between ACP and TE domains in modular polyketide synthases.
    Tran L; Tosin M; Spencer JB; Leadlay PF; Weissman KJ
    Chembiochem; 2008 Apr; 9(6):905-15. PubMed ID: 18348128
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The modules of trans-acyltransferase assembly lines redefined with a central acyl carrier protein.
    Vander Wood DA; Keatinge-Clay AT
    Proteins; 2018 Jun; 86(6):664-675. PubMed ID: 29524261
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.
    Arthur CJ; Szafranska AE; Long J; Mills J; Cox RJ; Findlow SC; Simpson TJ; Crump MP; Crosby J
    Chem Biol; 2006 Jun; 13(6):587-96. PubMed ID: 16793516
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Interactions of the acyl chain with the Saccharomyces cerevisiae acyl carrier protein.
    Perez DR; Leibundgut M; Wider G
    Biochemistry; 2015 Apr; 54(13):2205-13. PubMed ID: 25774789
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea.
    Pereda A; Summers RG; Stassi DL; Ruan X; Katz L
    Microbiology (Reading); 1998 Feb; 144 ( Pt 2)():543-553. PubMed ID: 9493390
    [TBL] [Abstract][Full Text] [Related]  

  • 35. In vivo and in vitro analysis of the hedamycin polyketide synthase.
    Das A; Khosla C
    Chem Biol; 2009 Nov; 16(11):1197-207. PubMed ID: 19942143
    [TBL] [Abstract][Full Text] [Related]  

  • 36. An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.
    Evans SE; Williams C; Arthur CJ; Burston SG; Simpson TJ; Crosby J; Crump MP
    Chembiochem; 2008 Oct; 9(15):2424-32. PubMed ID: 18770515
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
    Dreier J; Khosla C
    Biochemistry; 2000 Feb; 39(8):2088-95. PubMed ID: 10684659
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Roles of Conserved Active Site Residues in the Ketosynthase Domain of an Assembly Line Polyketide Synthase.
    Robbins T; Kapilivsky J; Cane DE; Khosla C
    Biochemistry; 2016 Aug; 55(32):4476-84. PubMed ID: 27441852
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Skipping in a hybrid polyketide synthase. Evidence for ACP-to-ACP chain transfer.
    Thomas I; Martin CJ; Wilkinson CJ; Staunton J; Leadlay PF
    Chem Biol; 2002 Jul; 9(7):781-7. PubMed ID: 12144921
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
    Zhang F; Ji H; Ali I; Deng Z; Bai L; Zheng J
    Chembiochem; 2020 May; 21(9):1309-1314. PubMed ID: 31777147
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.