BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1707 related articles for article (PubMed ID: 21565612)

  • 1. Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.
    Schlacher K; Christ N; Siaud N; Egashira A; Wu H; Jasin M
    Cell; 2011 May; 145(4):529-42. PubMed ID: 21565612
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25847274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25773776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The BRCA2 and CDKN1A-interacting protein (BCCIP) stabilizes stalled replication forks and prevents degradation of nascent DNA.
    Singh B; Roy Chowdhury S; Mansuri MS; Pillai SJ; Mehrotra S
    FEBS Lett; 2022 Aug; 596(16):2041-2055. PubMed ID: 35592921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
    Kolinjivadi AM; Sannino V; De Antoni A; Zadorozhny K; Kilkenny M; Técher H; Baldi G; Shen R; Ciccia A; Pellegrini L; Krejci L; Costanzo V
    Mol Cell; 2017 Sep; 67(5):867-881.e7. PubMed ID: 28757209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
    Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
    Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Replication fork reversal triggers fork degradation in BRCA2-defective cells.
    Mijic S; Zellweger R; Chappidi N; Berti M; Jacobs K; Mutreja K; Ursich S; Ray Chaudhuri A; Nussenzweig A; Janscak P; Lopes M
    Nat Commun; 2017 Oct; 8(1):859. PubMed ID: 29038466
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA.
    Lyu X; Lei KH; Biak Sang P; Shiva O; Chastain M; Chi P; Chai W
    EMBO J; 2021 Jan; 40(2):e103654. PubMed ID: 33210317
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Brca2, Rad51 and Mre11: performing balancing acts on replication forks.
    Costanzo V
    DNA Repair (Amst); 2011 Oct; 10(10):1060-5. PubMed ID: 21900052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.
    Pefani DE; O'Neill E
    Cell Cycle; 2015; 14(11):1624-30. PubMed ID: 25927241
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51.
    Kolinjivadi AM; Sannino V; de Antoni A; Técher H; Baldi G; Costanzo V
    FEBS Lett; 2017 Apr; 591(8):1083-1100. PubMed ID: 28079255
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.
    Taglialatela A; Alvarez S; Leuzzi G; Sannino V; Ranjha L; Huang JW; Madubata C; Anand R; Levy B; Rabadan R; Cejka P; Costanzo V; Ciccia A
    Mol Cell; 2017 Oct; 68(2):414-430.e8. PubMed ID: 29053959
    [TBL] [Abstract][Full Text] [Related]  

  • 13. E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells.
    Duan H; Mansour S; Reed R; Gillis MK; Parent B; Liu B; Sztupinszki Z; Birkbak N; Szallasi Z; Elia AEH; Garber JE; Pathania S
    J Cell Biol; 2020 Jun; 219(6):. PubMed ID: 32391871
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.
    Przetocka S; Porro A; Bolck HA; Walker C; Lezaja A; Trenner A; von Aesch C; Himmels SF; D'Andrea AD; Ceccaldi R; Altmeyer M; Sartori AA
    Mol Cell; 2018 Nov; 72(3):568-582.e6. PubMed ID: 30344097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
    Dungrawala H; Bhat KP; Le Meur R; Chazin WJ; Ding X; Sharan SK; Wessel SR; Sathe AA; Zhao R; Cortez D
    Mol Cell; 2017 Aug; 67(3):374-386.e5. PubMed ID: 28735897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells.
    Batenburg NL; Mersaoui SY; Walker JR; Coulombe Y; Hammond-Martel I; Wurtele H; Masson JY; Zhu XD
    Nucleic Acids Res; 2021 Dec; 49(22):12836-12854. PubMed ID: 34871413
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.
    Morales C; Ruiz-Torres M; Rodríguez-Acebes S; Lafarga V; Rodríguez-Corsino M; Megías D; Cisneros DA; Peters JM; Méndez J; Losada A
    J Biol Chem; 2020 Jan; 295(1):146-157. PubMed ID: 31757807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.
    Lemaçon D; Jackson J; Quinet A; Brickner JR; Li S; Yazinski S; You Z; Ira G; Zou L; Mosammaparast N; Vindigni A
    Nat Commun; 2017 Oct; 8(1):860. PubMed ID: 29038425
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2.
    Halder S; Sanchez A; Ranjha L; Reginato G; Ceppi I; Acharya A; Anand R; Cejka P
    Mol Cell; 2022 Oct; 82(19):3553-3565.e5. PubMed ID: 36070766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.
    Xu S; Wu X; Wu L; Castillo A; Liu J; Atkinson E; Paul A; Su D; Schlacher K; Komatsu Y; You MJ; Wang B
    Genes Dev; 2017 Jul; 31(14):1469-1482. PubMed ID: 28860160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 86.