These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 21566127)

  • 1. Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L.
    Jurkowska RZ; Rajavelu A; Anspach N; Urbanke C; Jankevicius G; Ragozin S; Nellen W; Jeltsch A
    J Biol Chem; 2011 Jul; 286(27):24200-7. PubMed ID: 21566127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multimerization of the dnmt3a DNA methyltransferase and its functional implications.
    Jeltsch A; Jurkowska RZ
    Prog Mol Biol Transl Sci; 2013; 117():445-64. PubMed ID: 23663978
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
    Jia D; Jurkowska RZ; Zhang X; Jeltsch A; Cheng X
    Nature; 2007 Sep; 449(7159):248-51. PubMed ID: 17713477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity.
    Nguyen TV; Yao S; Wang Y; Rolfe A; Selvaraj A; Darman R; Ke J; Warmuth M; Smith PG; Larsen NA; Yu L; Zhu P; Fekkes P; Vaillancourt FH; Bolduc DM
    J Biol Chem; 2019 Nov; 294(45):16966-16977. PubMed ID: 31582562
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation.
    Rajavelu A; Jurkowska RZ; Fritz J; Jeltsch A
    Nucleic Acids Res; 2012 Jan; 40(2):569-80. PubMed ID: 21926161
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction.
    Suetake I; Shinozaki F; Miyagawa J; Takeshima H; Tajima S
    J Biol Chem; 2004 Jun; 279(26):27816-23. PubMed ID: 15105426
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.
    Gowher H; Liebert K; Hermann A; Xu G; Jeltsch A
    J Biol Chem; 2005 Apr; 280(14):13341-8. PubMed ID: 15671018
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation.
    Holz-Schietinger C; Matje DM; Harrison MF; Reich NO
    J Biol Chem; 2011 Dec; 286(48):41479-41488. PubMed ID: 21979949
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.
    Chen T; Tsujimoto N; Li E
    Mol Cell Biol; 2004 Oct; 24(20):9048-58. PubMed ID: 15456878
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting.
    Hara S; Takano T; Fujikawa T; Yamada M; Wakai T; Kono T; Obata Y
    Hum Mol Genet; 2014 Jul; 23(14):3853-64. PubMed ID: 24599402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The R882H substitution in the human
    Sandoval JE; Reich NO
    J Biol Chem; 2019 Nov; 294(48):18207-18219. PubMed ID: 31640986
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for DNMT3A-mediated de novo DNA methylation.
    Zhang ZM; Lu R; Wang P; Yu Y; Chen D; Gao L; Liu S; Ji D; Rothbart SB; Wang Y; Wang GG; Song J
    Nature; 2018 Feb; 554(7692):387-391. PubMed ID: 29414941
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain.
    Otani J; Nankumo T; Arita K; Inamoto S; Ariyoshi M; Shirakawa M
    EMBO Rep; 2009 Nov; 10(11):1235-41. PubMed ID: 19834512
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dnmt3b Methylates DNA by a Noncooperative Mechanism, and Its Activity Is Unaffected by Manipulations at the Predicted Dimer Interface.
    Norvil AB; Petell CJ; Alabdi L; Wu L; Rossie S; Gowher H
    Biochemistry; 2018 Jul; 57(29):4312-4324. PubMed ID: 27768276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells.
    Veland N; Lu Y; Hardikar S; Gaddis S; Zeng Y; Liu B; Estecio MR; Takata Y; Lin K; Tomida MW; Shen J; Saha D; Gowher H; Zhao H; Chen T
    Nucleic Acids Res; 2019 Jan; 47(1):152-167. PubMed ID: 30321403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2.
    Rajavelu A; Lungu C; Emperle M; Dukatz M; Bröhm A; Broche J; Hanelt I; Parsa E; Schiffers S; Karnik R; Meissner A; Carell T; Rathert P; Jurkowska RZ; Jeltsch A
    Nucleic Acids Res; 2018 Sep; 46(17):9044-9056. PubMed ID: 30102379
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The inherent processivity of the human de novo methyltransferase 3A (DNMT3A) is enhanced by DNMT3L.
    Holz-Schietinger C; Reich NO
    J Biol Chem; 2010 Sep; 285(38):29091-100. PubMed ID: 20630873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction.
    Dukatz M; Holzer K; Choudalakis M; Emperle M; Lungu C; Bashtrykov P; Jeltsch A
    J Mol Biol; 2019 Dec; 431(24):5063-5074. PubMed ID: 31634469
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.
    Siddique AN; Jurkowska RZ; Jurkowski TP; Jeltsch A
    FEBS J; 2011 Jun; 278(12):2055-63. PubMed ID: 21481189
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity.
    Aapola U; Liiv I; Peterson P
    Nucleic Acids Res; 2002 Aug; 30(16):3602-8. PubMed ID: 12177302
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.