These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis. Alhawagri M; Yamanaka Y; Ballard D; Oltz E; Abu-Amer Y J Orthop Res; 2012 Apr; 30(4):554-60. PubMed ID: 21913221 [TBL] [Abstract][Full Text] [Related]
3. Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. Matta H; Gopalakrishnan R; Graham C; Tolani B; Khanna A; Yi H; Suo Y; Chaudhary PM PLoS One; 2012; 7(5):e36601. PubMed ID: 22590573 [TBL] [Abstract][Full Text] [Related]
4. Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis. Clohisy JC; Yamanaka Y; Faccio R; Abu-Amer Y J Orthop Res; 2006 Jul; 24(7):1358-65. PubMed ID: 16705717 [TBL] [Abstract][Full Text] [Related]
5. ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. Wu ZH; Wong ET; Shi Y; Niu J; Chen Z; Miyamoto S; Tergaonkar V Mol Cell; 2010 Oct; 40(1):75-86. PubMed ID: 20932476 [TBL] [Abstract][Full Text] [Related]
6. Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. Fan Y; Yu Y; Shi Y; Sun W; Xie M; Ge N; Mao R; Chang A; Xu G; Schneider MD; Zhang H; Fu S; Qin J; Yang J J Biol Chem; 2010 Feb; 285(8):5347-60. PubMed ID: 20038579 [TBL] [Abstract][Full Text] [Related]
7. Mitogen-activated protein (MAP) kinases mediate PMMA-induction of osteoclasts. Abbas S; Clohisy JC; Abu-Amer Y J Orthop Res; 2003 Nov; 21(6):1041-8. PubMed ID: 14554217 [TBL] [Abstract][Full Text] [Related]
8. NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2. Yang Y; Yin C; Pandey A; Abbott D; Sassetti C; Kelliher MA J Biol Chem; 2007 Dec; 282(50):36223-9. PubMed ID: 17947236 [TBL] [Abstract][Full Text] [Related]
9. Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO. Adapala NS; Swarnkar G; Arra M; Shen J; Mbalaviele G; Ke K; Abu-Amer Y Elife; 2020 Mar; 9():. PubMed ID: 32202502 [TBL] [Abstract][Full Text] [Related]
10. TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation. Mao R; Fan Y; Mou Y; Zhang H; Fu S; Yang J Cell Signal; 2011 Jan; 23(1):222-7. PubMed ID: 20837137 [TBL] [Abstract][Full Text] [Related]
11. Blockade of NF-κB and MAPK pathways by ulinastatin attenuates wear particle-stimulated osteoclast differentiation in vitro and in vivo. Ru JY; Xu HD; Shi D; Pan JB; Pan XJ; Wang YF Biosci Rep; 2016 Oct; 36(5):. PubMed ID: 27638499 [TBL] [Abstract][Full Text] [Related]
12. Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. Lamothe B; Besse A; Campos AD; Webster WK; Wu H; Darnay BG J Biol Chem; 2007 Feb; 282(6):4102-12. PubMed ID: 17135271 [TBL] [Abstract][Full Text] [Related]
13. Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling. Yamazaki K; Gohda J; Kanayama A; Miyamoto Y; Sakurai H; Yamamoto M; Akira S; Hayashi H; Su B; Inoue J Sci Signal; 2009 Oct; 2(93):ra66. PubMed ID: 19843958 [TBL] [Abstract][Full Text] [Related]
14. A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. Hinz M; Stilmann M; Arslan SÇ; Khanna KK; Dittmar G; Scheidereit C Mol Cell; 2010 Oct; 40(1):63-74. PubMed ID: 20932475 [TBL] [Abstract][Full Text] [Related]
15. Protein Kinase-Mediated Decision Between the Life and Death. Engin A Adv Exp Med Biol; 2021; 1275():1-33. PubMed ID: 33539010 [TBL] [Abstract][Full Text] [Related]
16. A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. Yang Y; Xia F; Hermance N; Mabb A; Simonson S; Morrissey S; Gandhi P; Munson M; Miyamoto S; Kelliher MA Mol Cell Biol; 2011 Jul; 31(14):2774-86. PubMed ID: 21606198 [TBL] [Abstract][Full Text] [Related]
17. Endotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expression. Xiong Y; Qiu F; Piao W; Song C; Wahl LM; Medvedev AE J Biol Chem; 2011 Mar; 286(10):7905-7916. PubMed ID: 21220427 [TBL] [Abstract][Full Text] [Related]
18. The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Sun L; Deng L; Ea CK; Xia ZP; Chen ZJ Mol Cell; 2004 May; 14(3):289-301. PubMed ID: 15125833 [TBL] [Abstract][Full Text] [Related]
19. Impediment of NEMO oligomerization inhibits osteoclastogenesis and osteolysis. Darwech I; Otero J; Alhawagri M; Dai S; Abu-Amer Y J Cell Biochem; 2009 Dec; 108(6):1337-45. PubMed ID: 19830703 [TBL] [Abstract][Full Text] [Related]
20. Blockade of JNK and NFAT pathways attenuates orthopedic particle-stimulated osteoclastogenesis of human osteoclast precursors and murine calvarial osteolysis. Yamanaka Y; Clohisy JC; Ito H; Matsuno T; Abu-Amer Y J Orthop Res; 2013 Jan; 31(1):67-72. PubMed ID: 22847537 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]