BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 21567966)

  • 1. 5',6'-nucleoside phosphonate analogues architecture: synthesis and comparative evaluation towards metabolic enzymes.
    Gallier F; Alexandre JA; El Amri C; Deville-Bonne D; Peyrottes S; Périgaud C
    ChemMedChem; 2011 Jun; 6(6):1094-106. PubMed ID: 21567966
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
    Topalis D; Pradère U; Roy V; Caillat C; Azzouzi A; Broggi J; Snoeck R; Andrei G; Lin J; Eriksson S; Alexandre JA; El-Amri C; Deville-Bonne D; Meyer P; Balzarini J; Agrofoglio LA
    J Med Chem; 2011 Jan; 54(1):222-32. PubMed ID: 21128666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase.
    Topalis D; Kumamoto H; Alexandre JA; Dugué L; Pochet S; Berteina-Raboin S; Agrofoglio LA; Deville-Bonne D
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1369-73. PubMed ID: 18066785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of 5-substituted 2'-deoxyuridine-5'- phosphonate analogues and evaluation of their antiviral activity.
    Poecke SV; Sinnaeve D; Martins JC; Balzarini J; Calenbergh SV
    Nucleosides Nucleotides Nucleic Acids; 2012; 31(3):256-72. PubMed ID: 22356239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Short synthesis and antiviral activity of acyclic phosphonic acid nucleoside analogues.
    Liu LJ; Yoo JC; Hong JH
    Nucleosides Nucleotides Nucleic Acids; 2009 Feb; 28(2):150-64. PubMed ID: 19219742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antiviral evaluation of 2'-C-methyl analogues of 5-alkynyl- and 6-alkylfurano- and pyrrolo[2,3-d]pyrimidine ribonucleosides.
    Januszczyk P; Fogt J; Boryski J; Izawa K; Onishi T; Neyts J; De Clercq E
    Nucleosides Nucleotides Nucleic Acids; 2009 May; 28(5):713-23. PubMed ID: 20183611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antiviral evaluation of novel cyclopropyl nucleosides, phosphonate nucleosides and phosphonic acid nucleosides.
    Hyun Oh C; Hong JH
    Arch Pharm (Weinheim); 2006 Sep; 339(9):507-12. PubMed ID: 16795106
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enantioselectivity of human AMP, dTMP and UMP-CMP kinases.
    Alexandre JA; Roy B; Topalis D; Pochet S; Périgaud C; Deville-Bonne D
    Nucleic Acids Res; 2007; 35(14):4895-904. PubMed ID: 17626051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antiviral evaluation of isatin ribonucleosides.
    de Oliveira MR; Torres JC; Garden SJ; dos Santos CV; Alves TR; Pinto AC; Pereira Hde S; Ferreira LR; Moussatché N; Frugulhetti IC; Ferreira VF; de Souza MC
    Nucleosides Nucleotides Nucleic Acids; 2002; 21(11-12):825-35. PubMed ID: 12537024
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site.
    Topalis D; Kumamoto H; Amaya Velasco MF; Dugué L; Haouz A; Alexandre JAC; Gallois-Montbrun S; Alzari PM; Pochet S; Agrofoglio LA; Deville-Bonne D
    FEBS J; 2007 Jul; 274(14):3704-3714. PubMed ID: 17608725
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of phosphonate analogues of the antiviral cyclopropane nucleoside A-5021.
    Onishi T; Sekiyama T; Tsuji T
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(8):1187-97. PubMed ID: 16270661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium.
    Hsu CH; Liou JY; Dutschman GE; Cheng YC
    Mol Pharmacol; 2005 Mar; 67(3):806-14. PubMed ID: 15550676
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme.
    Bertrand T; Briozzo P; Assairi L; Ofiteru A; Bucurenci N; Munier-Lehmann H; Golinelli-Pimpaneau B; Bârzu O; Gilles AM
    J Mol Biol; 2002 Feb; 315(5):1099-110. PubMed ID: 11827479
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An alternative pathway to ribonucleoside β-hydroxyphosphonate analogues and related prodrugs.
    Hospital A; Meurillon M; Peyrottes S; Périgaud C
    Org Lett; 2013 Sep; 15(18):4778-81. PubMed ID: 24015803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nucleoside diphosphate kinase and the activation of antiviral phosphonate analogs of nucleotides: binding mode and phosphorylation of tenofovir derivatives.
    Koch K; Chen Y; Feng JY; Borroto-Esoda K; Deville-Bonne D; Gallois-Montbrun S; Janin J; Moréra S
    Nucleosides Nucleotides Nucleic Acids; 2009 Aug; 28(8):776-92. PubMed ID: 20183617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates.
    Liou JY; Dutschman GE; Lam W; Jiang Z; Cheng YC
    Cancer Res; 2002 Mar; 62(6):1624-31. PubMed ID: 11912132
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication.
    Eldrup AB; Prhavc M; Brooks J; Bhat B; Prakash TP; Song Q; Bera S; Bhat N; Dande P; Cook PD; Bennett CF; Carroll SS; Ball RG; Bosserman M; Burlein C; Colwell LF; Fay JF; Flores OA; Getty K; LaFemina RL; Leone J; MacCoss M; McMasters DR; Tomassini JE; Von Langen D; Wolanski B; Olsen DB
    J Med Chem; 2004 Oct; 47(21):5284-97. PubMed ID: 15456273
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2'-Deoxy-2'-C-trifluoromethyl beta-D-ribonucleoside analogues: synthesis and antiviral evaluations.
    Jeannot F; Gosselin G; Mathé C
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):857-9. PubMed ID: 14565296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of (E)-3'-phosphonoalkenyl modified nucleoside phosphonates via a highly stereoselective olefin cross-metathesis reaction.
    Huang Q; Herdewijn P
    J Org Chem; 2011 May; 76(10):3742-53. PubMed ID: 21462931
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides.
    Hocek M; Silhár P; Shih IH; Mabery E; Mackman R
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5290-3. PubMed ID: 16905315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.