BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 21570838)

  • 1. Structure-activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: pyrrole regioisomers and propionic acid replacement.
    Sun X; Qiu J; Strong SA; Green LS; Wasley JW; Colagiovanni DB; Mutka SC; Blonder JP; Stout AM; Richards JP; Chun L; Rosenthal GJ
    Bioorg Med Chem Lett; 2011 Jun; 21(12):3671-5. PubMed ID: 21570838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities.
    Sun X; Qiu J; Strong SA; Green LS; Wasley JW; Blonder JP; Colagiovanni DB; Mutka SC; Stout AM; Richards JP; Rosenthal GJ
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5849-53. PubMed ID: 21855338
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: carboxamide modification.
    Sun X; Qiu J; Strong SA; Green LS; Wasley JW; Blonder JP; Colagiovanni DB; Stout AM; Mutka SC; Richards JP; Rosenthal GJ
    Bioorg Med Chem Lett; 2012 Mar; 22(6):2338-42. PubMed ID: 22342142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase.
    Green LS; Chun LE; Patton AK; Sun X; Rosenthal GJ; Richards JP
    Biochemistry; 2012 Mar; 51(10):2157-68. PubMed ID: 22335564
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of 5-(2-chloro-4'-(1H-imidazol-1-yl)-[1,1'-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD.
    Muthukaman N; Deshmukh S; Tondlekar S; Tambe M; Pisal D; Sarode N; Mhatre S; Chakraborti S; Shah D; Bhosale VM; Kulkarni A; Mahat MYA; Jadhav SB; Gudi GS; Khairatkar-Joshi N; Gharat LA
    Bioorg Med Chem Lett; 2018 Dec; 28(23-24):3766-3773. PubMed ID: 30340896
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation.
    Blonder JP; Mutka SC; Sun X; Qiu J; Green LH; Mehra NK; Boyanapalli R; Suniga M; Look K; Delany C; Richards JP; Looker D; Scoggin C; Rosenthal GJ
    BMC Pulm Med; 2014 Jan; 14():3. PubMed ID: 24405692
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1.
    Wiegard A; Hanekamp W; Griessbach K; Fabian J; Lehr M
    Eur J Med Chem; 2012 Feb; 48():153-63. PubMed ID: 22209272
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of s-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases.
    Sun X; Wasley JW; Qiu J; Blonder JP; Stout AM; Green LS; Strong SA; Colagiovanni DB; Richards JP; Mutka SC; Chun L; Rosenthal GJ
    ACS Med Chem Lett; 2011 May; 2(5):402-6. PubMed ID: 24900320
    [TBL] [Abstract][Full Text] [Related]  

  • 9. S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis.
    Saxena N; Won J; Choi S; Singh AK; Singh I
    Free Radic Biol Med; 2018 Jun; 121():57-68. PubMed ID: 29694854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma.
    Colagiovanni DB; Drolet DW; Langlois-Forget E; Piché MP; Looker D; Rosenthal GJ
    Regul Toxicol Pharmacol; 2012 Feb; 62(1):115-24. PubMed ID: 22210450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.
    Pegklidou K; Koukoulitsa C; Nicolaou I; Demopoulos VJ
    Bioorg Med Chem; 2010 Mar; 18(6):2107-2114. PubMed ID: 20189816
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of a Novel Inhibitor of Human Rhinovirus Replication and Inflammation in Airway Epithelial Cells.
    Yang Z; Bochkov YA; Voelker DR; Foster MW; Que LG
    Am J Respir Cell Mol Biol; 2019 Jan; 60(1):58-67. PubMed ID: 30156431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. O-Aminobenzoyl-S-nitrosoglutathione: A fluorogenic, cell permeable, pseudo-substrate for S-nitrosoglutathione reductase.
    Sun BL; Palmer L; Alam SR; Adekoya I; Brown-Steinke K; Periasamy A; Mutus B
    Free Radic Biol Med; 2017 Jul; 108():445-451. PubMed ID: 28419866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetic and cellular characterization of novel inhibitors of S-nitrosoglutathione reductase.
    Sanghani PC; Davis WI; Fears SL; Green SL; Zhai L; Tang Y; Martin E; Bryan NS; Sanghani SP
    J Biol Chem; 2009 Sep; 284(36):24354-62. PubMed ID: 19596685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase.
    Selness SR; Devraj RV; Devadas B; Walker JK; Boehm TL; Durley RC; Shieh H; Xing L; Rucker PV; Jerome KD; Benson AG; Marrufo LD; Madsen HM; Hitchcock J; Owen TJ; Christie L; Promo MA; Hickory BS; Alvira E; Naing W; Blevis-Bal R; Messing D; Yang J; Mao MK; Yalamanchili G; Vonder Embse R; Hirsch J; Saabye M; Bonar S; Webb E; Anderson G; Monahan JB
    Bioorg Med Chem Lett; 2011 Jul; 21(13):4066-71. PubMed ID: 21641211
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GSNOR and ALDH2 alleviate traumatic spinal cord injury.
    Khan M; Qiao F; Islam SMT; Dhammu TS; Kumar P; Won J; Singh AK; Singh I
    Brain Res; 2021 May; 1758():147335. PubMed ID: 33545099
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists.
    Rotstein DM; Melville CR; Padilla F; Cournoyer D; Lee EK; Lemoine R; Petersen AC; Setti LQ; Wanner J; Chen L; Filonova L; Loughhead DG; Manka J; Lin XF; Gleason S; Sankuratri S; Ji C; Derosier A; Dioszegi M; Heilek G; Jekle A; Berry P; Mau CI; Weller P
    Bioorg Med Chem Lett; 2010 May; 20(10):3116-9. PubMed ID: 20417098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke.
    Khan M; Kumar P; Qiao F; Islam SMT; Singh AK; Won JS; Feng W; Singh I
    Brain Res; 2020 Aug; 1741():146879. PubMed ID: 32418890
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and SAR studies of diarylpyrrole anticoccidial agents.
    Qian X; Liang GB; Feng D; Fisher M; Crumley T; Rattray S; Dulski PM; Gurnett A; Leavitt PS; Liberator PA; Misura AS; Samaras S; Tamas T; Schmatz DM; Wyvratt M; Biftu T
    Bioorg Med Chem Lett; 2006 May; 16(10):2817-21. PubMed ID: 16517161
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Crucial Role of SlGSNOR in Regulating Postharvest Tomato Fruit Ripening.
    Liu Z; Huang D; Yao Y; Pan X; Zhang Y; Huang Y; Ding Z; Wang C; Liao W
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473974
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 8.