143 related articles for article (PubMed ID: 21571536)
1. Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).
Kouznetsova VL; Tsigelny IF; Nagle MA; Nigam SK
Bioorg Med Chem; 2011 Jun; 19(11):3320-40. PubMed ID: 21571536
[TBL] [Abstract][Full Text] [Related]
2. Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning.
Nigam AK; Li JG; Lall K; Shi D; Bush KT; Bhatnagar V; Abagyan R; Nigam SK
J Biol Chem; 2020 Feb; 295(7):1829-1842. PubMed ID: 31896576
[TBL] [Abstract][Full Text] [Related]
3. Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue.
Nagle MA; Wu W; Eraly SA; Nigam SK
Neurosci Lett; 2013 Feb; 534():133-8. PubMed ID: 23196129
[TBL] [Abstract][Full Text] [Related]
4. Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury.
Torres AM; Dnyanmote AV; Bush KT; Wu W; Nigam SK
J Biol Chem; 2011 Jul; 286(30):26391-5. PubMed ID: 21652719
[TBL] [Abstract][Full Text] [Related]
5. An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.
Liu HC; Jamshidi N; Chen Y; Eraly SA; Cho SY; Bhatnagar V; Wu W; Bush KT; Abagyan R; Palsson BO; Nigam SK
J Biol Chem; 2016 Sep; 291(37):19474-86. PubMed ID: 27440044
[TBL] [Abstract][Full Text] [Related]
6. Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.
Tsigelny IF; Kovalskyy D; Kouznetsova VL; Balinskyi O; Sharikov Y; Bhatnagar V; Nigam SK
Cell Biochem Biophys; 2011 Nov; 61(2):251-9. PubMed ID: 21499753
[TBL] [Abstract][Full Text] [Related]
7. Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].
Xu G; Bhatnagar V; Wen G; Hamilton BA; Eraly SA; Nigam SK
Kidney Int; 2005 Oct; 68(4):1491-9. PubMed ID: 16164626
[TBL] [Abstract][Full Text] [Related]
8. Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach.
Liu HC; Goldenberg A; Chen Y; Lun C; Wu W; Bush KT; Balac N; Rodriguez P; Abagyan R; Nigam SK
J Pharmacol Exp Ther; 2016 Oct; 359(1):215-29. PubMed ID: 27488918
[TBL] [Abstract][Full Text] [Related]
9. Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3.
Granados JC; Richelle A; Gutierrez JM; Zhang P; Zhang X; Bhatnagar V; Lewis NE; Nigam SK
J Biol Chem; 2021; 296():100575. PubMed ID: 33757768
[TBL] [Abstract][Full Text] [Related]
10. Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1).
Wikoff WR; Nagle MA; Kouznetsova VL; Tsigelny IF; Nigam SK
J Proteome Res; 2011 Jun; 10(6):2842-51. PubMed ID: 21476605
[TBL] [Abstract][Full Text] [Related]
11. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.
Eraly SA; Vallon V; Vaughn DA; Gangoiti JA; Richter K; Nagle M; Monte JC; Rieg T; Truong DM; Long JM; Barshop BA; Kaler G; Nigam SK
J Biol Chem; 2006 Feb; 281(8):5072-83. PubMed ID: 16354673
[TBL] [Abstract][Full Text] [Related]
12. Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis.
Ahn SY; Jamshidi N; Mo ML; Wu W; Eraly SA; Dnyanmote A; Bush KT; Gallegos TF; Sweet DH; Palsson BØ; Nigam SK
J Biol Chem; 2011 Sep; 286(36):31522-31. PubMed ID: 21757732
[TBL] [Abstract][Full Text] [Related]
13. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors.
Wu W; Bush KT; Liu HC; Zhu C; Abagyan R; Nigam SK
Drug Metab Dispos; 2015 Dec; 43(12):1855-63. PubMed ID: 26358290
[TBL] [Abstract][Full Text] [Related]
14. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity.
Wang X; Han L; Li G; Peng W; Gao X; Klaassen CD; Fan G; Zhang Y
Toxicol Sci; 2018 Feb; 161(2):321-334. PubMed ID: 29045746
[TBL] [Abstract][Full Text] [Related]
15. In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1.
Li L; Song F; Tu M; Wang K; Zhao L; Wu X; Zhou H; Xia Z; Jiang H
Int J Pharm; 2014 Apr; 465(1-2):5-10. PubMed ID: 24530383
[TBL] [Abstract][Full Text] [Related]
16. Drug Clearance from Cerebrospinal Fluid Mediated by Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) at Arachnoid Membrane of Rats.
Zhang Z; Tachikawa M; Uchida Y; Terasaki T
Mol Pharm; 2018 Mar; 15(3):911-922. PubMed ID: 29436232
[TBL] [Abstract][Full Text] [Related]
17. Interaction of organic cations with organic anion transporters.
Ahn SY; Eraly SA; Tsigelny I; Nigam SK
J Biol Chem; 2009 Nov; 284(45):31422-30. PubMed ID: 19737926
[TBL] [Abstract][Full Text] [Related]
18. A key role for the transporter OAT1 in systemic lipid metabolism.
Granados JC; Nigam AK; Bush KT; Jamshidi N; Nigam SK
J Biol Chem; 2021; 296():100603. PubMed ID: 33785360
[TBL] [Abstract][Full Text] [Related]
19. Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes.
Jin C; Wei L; Ohgaki R; Tominaga H; Xu M; Okuda S; Okanishi H; Kawamoto Y; He X; Nagamori S; Kanai Y
J Pharmacol Exp Ther; 2020 Dec; 375(3):451-462. PubMed ID: 32981893
[TBL] [Abstract][Full Text] [Related]
20. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange.
Hotchkiss AG; Gao T; Khan U; Berrigan L; Li M; Ingraham L; Pelis RM
Drug Metab Dispos; 2015 Dec; 43(12):1847-54. PubMed ID: 26370539
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
