BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 21573497)

  • 1. Synergism between K-rasVal12 and mutant Apc accelerates murine large intestinal tumourigenesis.
    Luo F; Poulogiannis G; Ye H; Hamoudi R; Arends MJ
    Oncol Rep; 2011 Jul; 26(1):125-33. PubMed ID: 21573497
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.
    Luo F; Brooks DG; Ye H; Hamoudi R; Poulogiannis G; Patek CE; Winton DJ; Arends MJ
    Int J Exp Pathol; 2009 Oct; 90(5):558-74. PubMed ID: 19765110
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.
    Luo F; Brooks DG; Ye H; Hamoudi R; Poulogiannis G; Patek CE; Winton DJ; Arends MJ
    Oncogene; 2007 Jun; 26(30):4415-27. PubMed ID: 17297472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.
    Luo F; Poulogiannis G; Ye H; Hamoudi R; Zhang W; Dong G; Arends MJ
    J Pathol; 2011 Feb; 223(3):390-9. PubMed ID: 21171084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.
    Luo F; Ye H; Hamoudi R; Dong G; Zhang W; Patek CE; Poulogiannis G; Arends MJ
    J Pathol; 2010 Apr; 220(5):542-50. PubMed ID: 20087880
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.
    Janssen KP; Alberici P; Fsihi H; Gaspar C; Breukel C; Franken P; Rosty C; Abal M; El Marjou F; Smits R; Louvard D; Fodde R; Robine S
    Gastroenterology; 2006 Oct; 131(4):1096-109. PubMed ID: 17030180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BCL9-2 promotes early stages of intestinal tumor progression.
    Brembeck FH; Wiese M; Zatula N; Grigoryan T; Dai Y; Fritzmann J; Birchmeier W
    Gastroenterology; 2011 Oct; 141(4):1359-70, 1370.e1-3. PubMed ID: 21703997
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia.
    Kim SH; Roth KA; Moser AR; Gordon JI
    J Cell Biol; 1993 Nov; 123(4):877-93. PubMed ID: 8227147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis.
    Zeilstra J; Joosten SP; Dokter M; Verwiel E; Spaargaren M; Pals ST
    Cancer Res; 2008 May; 68(10):3655-61. PubMed ID: 18483247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional profiling of the transition from normal intestinal epithelia to adenomas and carcinomas in the APCMin/+ mouse.
    Paoni NF; Feldman MW; Gutierrez LS; Ploplis VA; Castellino FJ
    Physiol Genomics; 2003 Nov; 15(3):228-35. PubMed ID: 13130079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. WNT signaling controls expression of pro-apoptotic BOK and BAX in intestinal cancer.
    Zeilstra J; Joosten SP; Wensveen FM; Dessing MC; Schütze DM; Eldering E; Spaargaren M; Pals ST
    Biochem Biophys Res Commun; 2011 Mar; 406(1):1-6. PubMed ID: 21184732
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.
    Patek CE; Arends MJ; Rose L; Luo F; Walker M; Devenney PS; Berry RL; Lawrence NJ; Ridgway RA; Sansom OJ; Hooper ML
    BMC Gastroenterol; 2008 Jun; 8():24. PubMed ID: 18554389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
    Joosten SPJ; Zeilstra J; van Andel H; Mijnals RC; Zaunbrecher J; Duivenvoorden AAM; van de Wetering M; Clevers H; Spaargaren M; Pals ST
    Gastroenterology; 2017 Oct; 153(4):1040-1053.e4. PubMed ID: 28716720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
    Martinez G; Wijesinghe M; Turner K; Abud HE; Taketo MM; Noda T; Robinson ML; de Iongh RU
    Invest Ophthalmol Vis Sci; 2009 Oct; 50(10):4794-806. PubMed ID: 19515997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways.
    Araki Y; Okamura S; Hussain SP; Nagashima M; He P; Shiseki M; Miura K; Harris CC
    Cancer Res; 2003 Feb; 63(3):728-34. PubMed ID: 12566320
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice.
    Koehl GE; Spitzner M; Ousingsawat J; Schreiber R; Geissler EK; Kunzelmann K
    Oncogene; 2010 Mar; 29(10):1553-60. PubMed ID: 19966863
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic alterations in gastric adenomas of intestinal and foveolar phenotypes.
    Abraham SC; Park SJ; Lee JH; Mugartegui L; Wu TT
    Mod Pathol; 2003 Aug; 16(8):786-95. PubMed ID: 12920223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutational activation of the RAS-RAF-MAPK and the Wnt pathway in small intestinal adenocarcinomas.
    Bläker H; Helmchen B; Bönisch A; Aulmann S; Penzel R; Otto HF; Rieker RJ
    Scand J Gastroenterol; 2004 Aug; 39(8):748-53. PubMed ID: 15513360
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.
    Li Q; Ishikawa TO; Oshima M; Taketo MM
    Cancer Res; 2005 Oct; 65(19):8622-7. PubMed ID: 16204028
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88.
    Rakoff-Nahoum S; Medzhitov R
    Science; 2007 Jul; 317(5834):124-7. PubMed ID: 17615359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.