These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 21576250)

  • 1. The N-terminal nucleophile serine of cephalosporin acylase executes the second autoproteolytic cleavage and acylpeptide hydrolysis.
    Yin J; Deng Z; Zhao G; Huang X
    J Biol Chem; 2011 Jul; 286(27):24476-86. PubMed ID: 21576250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determination of the second autoproteolytic cleavage site of cephalosporin C acylase and the effect of deleting its flanking residues in the α-C-terminal region.
    Zhang J; Yu H; Wang Y; Luo H; Shen Z
    J Biotechnol; 2014 Aug; 184():138-45. PubMed ID: 24874096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries.
    Kim JK; Yang IS; Shin HJ; Cho KJ; Ryu EK; Kim SH; Park SS; Kim KH
    Proc Natl Acad Sci U S A; 2006 Feb; 103(6):1732-7. PubMed ID: 16446446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of alpha-amino group of the N-terminal serine of beta subunit for enzyme catalysis and autoproteolytic activation of glutaryl 7-aminocephalosporanic acid acylase.
    Lee YS; Kim HW; Park SS
    J Biol Chem; 2000 Dec; 275(50):39200-6. PubMed ID: 10991936
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family.
    Kim Y; Kim S; Earnest TN; Hol WG
    J Biol Chem; 2002 Jan; 277(4):2823-9. PubMed ID: 11706000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of a slow processing precursor penicillin acylase from Escherichia coli reveals the linker peptide blocking the active-site cleft.
    Hewitt L; Kasche V; Lummer K; Lewis RJ; Murshudov GN; Verma CS; Dodson GG; Wilson KS
    J Mol Biol; 2000 Sep; 302(4):887-98. PubMed ID: 10993730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A bound water molecule is crucial in initiating autocatalytic precursor activation in an N-terminal hydrolase.
    Yoon J; Oh B; Kim K; Park J; Han D; Kim KK; Cha SS; Lee D; Kim Y
    J Biol Chem; 2004 Jan; 279(1):341-7. PubMed ID: 14534294
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo post-translational processing and subunit reconstitution of cephalosporin acylase from Pseudomonas sp. 130.
    Li Y; Chen J; Jiang W; Mao X; Zhao G; Wang E
    Eur J Biochem; 1999 Jun; 262(3):713-9. PubMed ID: 10411632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation.
    Kim JK; Yang IS; Rhee S; Dauter Z; Lee YS; Park SS; Kim KH
    Biochemistry; 2003 Apr; 42(14):4084-93. PubMed ID: 12680762
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural features of cephalosporin acylase reveal the basis of autocatalytic activation.
    Cho KJ; Kim JK; Lee JH; Shin HJ; Park SS; Kim KH
    Biochem Biophys Res Commun; 2009 Dec; 390(2):342-8. PubMed ID: 19800869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two-step autocatalytic processing of the glutaryl 7-aminocephalosporanic acid acylase from Pseudomonas sp. strain GK16.
    Lee YS; Park SS
    J Bacteriol; 1998 Sep; 180(17):4576-82. PubMed ID: 9721298
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity.
    Golden E; Paterson R; Tie WJ; Anandan A; Flematti G; Molla G; Rosini E; Pollegioni L; Vrielink A
    Biochem J; 2013 Apr; 451(2):217-26. PubMed ID: 23373797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Active site residues of cephalosporin acylase are critical not only for enzymatic catalysis but also for post-translational modification.
    Kim S; Kim Y
    J Biol Chem; 2001 Dec; 276(51):48376-81. PubMed ID: 11604409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The 2.0 A crystal structure of cephalosporin acylase.
    Kim Y; Yoon K; Khang Y; Turley S; Hol WG
    Structure; 2000 Oct; 8(10):1059-68. PubMed ID: 11080627
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of penicillin G acylase from the Bro1 mutant strain of Providencia rettgeri.
    McDonough MA; Klei HE; Kelly JA
    Protein Sci; 1999 Oct; 8(10):1971-81. PubMed ID: 10548042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. His23beta and Glu455beta of the Pseudomonas sp. 130 glutaryl-7-amino cephalosporanic acid acylase are crucially important for efficient autoproteolysis and enzymatic catalysis.
    Mao X; Wang W; Jiang W; Zhao GP
    Protein J; 2004 Apr; 23(3):197-204. PubMed ID: 15200051
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A highly active adipyl-cephalosporin acylase obtained via rational randomization.
    Otten LG; Sio CF; Reis CR; Koch G; Cool RH; Quax WJ
    FEBS J; 2007 Nov; 274(21):5600-10. PubMed ID: 17922842
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Strategic manipulation of an industrial biocatalyst--evolution of a cephalosporin C acylase.
    Conti G; Pollegioni L; Molla G; Rosini E
    FEBS J; 2014 May; 281(10):2443-55. PubMed ID: 24684708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues.
    Oh B; Kim K; Park J; Yoon J; Han D; Kim Y
    Biochem Biophys Res Commun; 2004 Jun; 319(2):486-92. PubMed ID: 15178432
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure mediation in substrate binding and post-translational processing of penicillin acylases: Information from mutant structures of Kluyvera citrophila penicillin G acylase.
    Chand D; Varshney N; Ramasamy S; Panigrahi P; Brannigan JA; Wilkinson AJ; Suresh CG
    Protein Sci; 2015 Oct; 24(10):1660-70. PubMed ID: 26243007
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.