BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 21586569)

  • 1. Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.
    Yu Y; Li WG; Chen Z; Cao H; Yang H; Jiang H; Xu TL
    J Biol Chem; 2011 Jul; 286(28):24996-5006. PubMed ID: 21586569
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A nonproton ligand sensor in the acid-sensing ion channel.
    Yu Y; Chen Z; Li WG; Cao H; Feng EG; Yu F; Liu H; Jiang H; Xu TL
    Neuron; 2010 Oct; 68(1):61-72. PubMed ID: 20920791
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3.
    Callejo G; Pattison LA; Greenhalgh JC; Chakrabarti S; Andreopoulou E; Hockley JRF; Smith ESJ; Rahman T
    Biochem Pharmacol; 2020 Apr; 174():113834. PubMed ID: 32027884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline.
    Alijevic O; Kellenberger S
    J Biol Chem; 2012 Oct; 287(43):36059-70. PubMed ID: 22948146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heteroarylguanidines as Allosteric Modulators of ASIC1a and ASIC3 Channels.
    Alijevic O; Hammoud H; Vaithia A; Trendafilov V; Bollenbach M; Schmitt M; Bihel F; Kellenberger S
    ACS Chem Neurosci; 2018 Jun; 9(6):1357-1365. PubMed ID: 29566331
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.
    Li WG; Yu Y; Huang C; Cao H; Xu TL
    J Biol Chem; 2011 Dec; 286(49):42635-42646. PubMed ID: 21998313
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protons and Psalmotoxin-1 reveal nonproton ligand stimulatory sites in chicken acid-sensing ion channel: Implication for simultaneous modulation in ASICs.
    Smith RN; Gonzales EB
    Channels (Austin); 2014; 8(1):49-61. PubMed ID: 24262969
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The nonproton ligand of acid-sensing ion channel 3 activates mollusk-specific FaNaC channels via a mechanism independent of the native FMRFamide peptide.
    Yang XN; Niu YY; Liu Y; Yang Y; Wang J; Cheng XY; Liang H; Wang HS; Hu YM; Lu XY; Zhu MX; Xu TL; Tian Y; Yu Y
    J Biol Chem; 2017 Dec; 292(52):21662-21675. PubMed ID: 29123030
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain.
    Li WG; Yu Y; Zhang ZD; Cao H; Xu TL
    Mol Pain; 2010 Dec; 6():88. PubMed ID: 21143836
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ).
    Besson T; Lingueglia E; Salinas M
    Neuropharmacology; 2017 Oct; 125():429-440. PubMed ID: 28802647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiple regulatory actions of 2-guanidine-4-methylquinazoline (GMQ), an agonist of acid-sensing ion channel type 3, on ionic currents in pituitary GH
    So EC; Wang Y; Yang LQ; So KH; Lo YC; Wu SN
    Biochem Pharmacol; 2018 May; 151():79-88. PubMed ID: 29477572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serotonin facilitates peripheral pain sensitivity in a manner that depends on the nonproton ligand sensing domain of ASIC3 channel.
    Wang X; Li WG; Yu Y; Xiao X; Cheng J; Zeng WZ; Peng Z; Xi Zhu M; Xu TL
    J Neurosci; 2013 Mar; 33(10):4265-79. PubMed ID: 23467344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels.
    Yang Y; Yu Y; Cheng J; Liu Y; Liu DS; Wang J; Zhu MX; Wang R; Xu TL
    J Biol Chem; 2012 Apr; 287(18):14443-55. PubMed ID: 22399291
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Non-proton ligand-sensing domain of acid-sensing ion channel 3 is required for itch sensation.
    Lei Z; Sami Shaikh A; Zheng W; Yu X; Yu J; Li J
    J Neurochem; 2016 Dec; 139(6):1093-1101. PubMed ID: 27770439
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ASIC3 Mediates Itch Sensation in Response to Coincident Stimulation by Acid and Nonproton Ligand.
    Peng Z; Li WG; Huang C; Jiang YM; Wang X; Zhu MX; Cheng X; Xu TL
    Cell Rep; 2015 Oct; 13(2):387-98. PubMed ID: 26440887
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Conorfamide RPRFa Stabilizes the Open Conformation of Acid-Sensing Ion Channel 3 via the Nonproton Ligand-Sensing Domain.
    Reiners M; Margreiter MA; Oslender-Bujotzek A; Rossetti G; GrĂ¼nder S; Schmidt A
    Mol Pharmacol; 2018 Oct; 94(4):1114-1124. PubMed ID: 30012583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Na
    Elkhatib W; Smith CL; Senatore A
    J Biol Chem; 2019 Nov; 294(44):16320-16336. PubMed ID: 31527080
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exploration of the Peptide Recognition of an Amiloride-sensitive FMRFamide Peptide-gated Sodium Channel.
    Niu YY; Yang Y; Liu Y; Huang LD; Yang XN; Fan YZ; Cheng XY; Cao P; Hu YM; Li L; Lu XY; Tian Y; Yu Y
    J Biol Chem; 2016 Apr; 291(14):7571-82. PubMed ID: 26867576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism.
    Yang H; Yu Y; Li WG; Yu F; Cao H; Xu TL; Jiang H
    PLoS Biol; 2009 Jul; 7(7):e1000151. PubMed ID: 19597538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator.
    Agharkar AS; Gonzales EB
    J Pharmacol Sci; 2017 Mar; 133(3):184-186. PubMed ID: 28259560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.