BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

88 related articles for article (PubMed ID: 21586901)

  • 1. Microarray coupled with methyl-CpG targeted transcriptional activation (MeTA-array) identifies hypermethylated genes containing the stringent criteria of CpG islands at high frequency.
    Sato Y; Horii A; Fukushige S
    Epigenetics; 2011 Jun; 6(6):752-9. PubMed ID: 21586901
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of epigenetically silenced genes in human pancreatic cancer by a novel method "microarray coupled with methyl-CpG targeted transcriptional activation" (MeTA-array).
    Shimizu H; Horii A; Sunamura M; Motoi F; Egawa S; Unno M; Fukushige S
    Biochem Biophys Res Commun; 2011 Jul; 411(1):162-7. PubMed ID: 21723258
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methyl-CpG targeted transcriptional activation allows re-expression of tumor suppressor genes in human cancer cells.
    Fukushige S; Kondo E; Horii A
    Biochem Biophys Res Commun; 2008 Dec; 377(2):600-605. PubMed ID: 18929535
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted TET oxidase activity through methyl-CpG-binding domain extensively suppresses cancer cell proliferation.
    Mizuguchi Y; Saiki Y; Horii A; Fukushige S
    Cancer Med; 2016 Sep; 5(9):2522-33. PubMed ID: 27457352
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methyl-CpG targeted recruitment of p300 reactivates tumor suppressor genes in human cancer cells.
    Fukushige S; Kondo E; Horii A
    Biochem Biophys Res Commun; 2009 Feb; 379(4):1021-6. PubMed ID: 19146826
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CpG island promoter methylation and silencing of 14-3-3sigma gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2.
    Pulukuri SM; Rao JS
    Oncogene; 2006 Aug; 25(33):4559-72. PubMed ID: 16786000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia.
    Gebhard C; Schwarzfischer L; Pham TH; Schilling E; Klug M; Andreesen R; Rehli M
    Cancer Res; 2006 Jun; 66(12):6118-28. PubMed ID: 16778185
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer.
    Stirzaker C; Song JZ; Ng W; Du Q; Armstrong NJ; Locke WJ; Statham AL; French H; Pidsley R; Valdes-Mora F; Zotenko E; Clark SJ
    Oncogene; 2017 Mar; 36(10):1328-1338. PubMed ID: 27593931
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.
    Magdinier F; Wolffe AP
    Proc Natl Acad Sci U S A; 2001 Apr; 98(9):4990-5. PubMed ID: 11309512
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA methylation-dependent epigenetic regulation of gene expression in MCF-7 breast cancer cells.
    Rivenbark AG; Jones WD; Risher JD; Coleman WB
    Epigenetics; 2006; 1(1):32-44. PubMed ID: 17998816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.
    Derks S; Bosch LJ; Niessen HE; Moerkerk PT; van den Bosch SM; Carvalho B; Mongera S; Voncken JW; Meijer GA; de Bruïne AP; Herman JG; van Engeland M
    Carcinogenesis; 2009 Jun; 30(6):1041-8. PubMed ID: 19329758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites.
    Moriguchi K; Yamashita S; Tsujino Y; Tatematsu M; Ushijima T
    Cancer Lett; 2007 May; 249(2):178-87. PubMed ID: 16971039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer.
    Lopez-Serra L; Ballestar E; Fraga MF; Alaminos M; Setien F; Esteller M
    Cancer Res; 2006 Sep; 66(17):8342-6. PubMed ID: 16951140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
    Yuan J; Luo RZ; Fujii S; Wang L; Hu W; Andreeff M; Pan Y; Kadota M; Oshimura M; Sahin AA; Issa JP; Bast RC; Yu Y
    Cancer Res; 2003 Jul; 63(14):4174-80. PubMed ID: 12874023
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Promoter CpG-Site Methylation of the KAI1 Metastasis Suppressor Gene Contributes to Its Epigenetic Repression in Prostate Cancer.
    Lee J; Lee MS; Jeoung DI; Kim YM; Lee H
    Prostate; 2017 Mar; 77(4):350-360. PubMed ID: 27813113
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer.
    Bae MG; Kim JY; Choi JK
    BMC Med Genomics; 2016 Aug; 9 Suppl 1(Suppl 1):38. PubMed ID: 27534853
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines.
    Mikata R; Yokosuka O; Fukai K; Imazeki F; Arai M; Tada M; Kurihara T; Zhang K; Kanda T; Saisho H
    Int J Cancer; 2006 Oct; 119(7):1616-22. PubMed ID: 16671088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions.
    Chatagnon A; Perriaud L; Nazaret N; Croze S; Benhattar J; Lachuer J; Dante R
    Epigenetics; 2011 Nov; 6(11):1295-307. PubMed ID: 22048253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CpG methylation prevents YY1-mediated transcriptional activation of the vimentin promoter.
    Sekimata M; Murakami-Sekimata A; Homma Y
    Biochem Biophys Res Commun; 2011 Nov; 414(4):767-72. PubMed ID: 22005459
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma.
    Fukai K; Yokosuka O; Chiba T; Hirasawa Y; Tada M; Imazeki F; Kataoka H; Saisho H
    Cancer Res; 2003 Dec; 63(24):8674-9. PubMed ID: 14695180
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.