These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 21593445)

  • 1. Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.
    Bourcier C; Griseri P; Grépin R; Bertolotto C; Mazure N; Pagès G
    Am J Physiol Cell Physiol; 2011 Sep; 301(3):C609-18. PubMed ID: 21593445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways.
    Deleault KM; Skinner SJ; Brooks SA
    Mol Immunol; 2008 Jan; 45(1):13-24. PubMed ID: 17606294
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor CI-1040 in hepatocellular carcinoma.
    Ou DL; Shen YC; Liang JD; Liou JY; Yu SL; Fan HH; Wang DS; Lu YS; Hsu C; Cheng AL
    Clin Cancer Res; 2009 Sep; 15(18):5820-8. PubMed ID: 19737956
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation.
    Essafi-Benkhadir K; Onesto C; Stebe E; Moroni C; Pagès G
    Mol Biol Cell; 2007 Nov; 18(11):4648-58. PubMed ID: 17855506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.
    Sanduja S; Kaza V; Dixon DA
    Aging (Albany NY); 2009 Sep; 1(9):803-17. PubMed ID: 20157568
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.
    Smalley KS; Xiao M; Villanueva J; Nguyen TK; Flaherty KT; Letrero R; Van Belle P; Elder DE; Wang Y; Nathanson KL; Herlyn M
    Oncogene; 2009 Jan; 28(1):85-94. PubMed ID: 18794803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bi-phased regulation of the post-transcriptional inflammatory response by Tristetraprolin levels.
    Mahmoud L; Moghrabi W; Khabar KSA; Hitti EG
    RNA Biol; 2019 Mar; 16(3):309-319. PubMed ID: 30664390
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P; Arienti C; Amadori D; Fabbri F; Carloni S; Tesei A; Vannini I; Silvestrini R; Zoli W
    J Cell Physiol; 2009 Jul; 220(1):214-21. PubMed ID: 19288493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic potential of MEK inhibition in acute myelogenous leukemia: rationale for "vertical" and "lateral" combination strategies.
    Ricciardi MR; Scerpa MC; Bergamo P; Ciuffreda L; Petrucci MT; Chiaretti S; Tavolaro S; Mascolo MG; Abrams SL; Steelman LS; Tsao T; Marchetti A; Konopleva M; Del Bufalo D; Cognetti F; Foà R; Andreeff M; McCubrey JA; Tafuri A; Milella M
    J Mol Med (Berl); 2012 Oct; 90(10):1133-44. PubMed ID: 22399013
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sorafenib inhibits activation of human peripheral blood T cells by targeting LCK phosphorylation.
    Zhao W; Gu YH; Song R; Qu BQ; Xu Q
    Leukemia; 2008 Jun; 22(6):1226-33. PubMed ID: 18337760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tristetraprolin down-regulates IL-23 expression in colon cancer cells.
    Lee HH; Yang SS; Vo MT; Cho WJ; Lee BJ; Leem SH; Lee SH; Cha HJ; Park JW
    Mol Cells; 2013 Dec; 36(6):571-6. PubMed ID: 24292977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PIM2 interacts with tristetraprolin and promotes breast cancer tumorigenesis.
    Ren C; Yang T; Qiao P; Wang L; Han X; Lv S; Sun Y; Liu Z; Du Y; Yu Z
    Mol Oncol; 2018 May; 12(5):690-704. PubMed ID: 29570932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of protein kinase Cdelta reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages.
    Leppänen T; Jalonen U; Korhonen R; Tuominen RK; Moilanen E
    Eur J Pharmacol; 2010 Feb; 628(1-3):220-5. PubMed ID: 19925787
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells.
    Lee SR; Jin H; Kim WT; Kim WJ; Kim SZ; Leem SH; Kim SM
    Int J Oncol; 2018 Sep; 53(3):1269-1278. PubMed ID: 29956753
    [TBL] [Abstract][Full Text] [Related]  

  • 15. C-Raf is associated with disease progression and cell proliferation in a subset of melanomas.
    Jilaveanu LB; Zito CR; Aziz SA; Conrad PJ; Schmitz JC; Sznol M; Camp RL; Rimm DL; Kluger HM
    Clin Cancer Res; 2009 Sep; 15(18):5704-13. PubMed ID: 19737955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drosophila eyes absent is a novel mRNA target of the tristetraprolin (TTP) protein DTIS11.
    Yeh PA; Yang WH; Chiang PY; Wang SC; Chang MS; Chang CJ
    Int J Biol Sci; 2012; 8(5):606-19. PubMed ID: 22553461
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways.
    Brook M; Tchen CR; Santalucia T; McIlrath J; Arthur JS; Saklatvala J; Clark AR
    Mol Cell Biol; 2006 Mar; 26(6):2408-18. PubMed ID: 16508015
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY43-9006).
    Murphy DA; Makonnen S; Lassoued W; Feldman MD; Carter C; Lee WM
    Am J Pathol; 2006 Nov; 169(5):1875-85. PubMed ID: 17071608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.
    Hitti E; Iakovleva T; Brook M; Deppenmeier S; Gruber AD; Radzioch D; Clark AR; Blackshear PJ; Kotlyarov A; Gaestel M
    Mol Cell Biol; 2006 Mar; 26(6):2399-407. PubMed ID: 16508014
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients.
    Griseri P; Bourcier C; Hieblot C; Essafi-Benkhadir K; Chamorey E; Touriol C; Pagès G
    Hum Mol Genet; 2011 Dec; 20(23):4556-68. PubMed ID: 21875902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.