BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 21595014)

  • 21. DNA damage response as a biomarker in treatment of leukemias.
    Halicka HD; Ozkaynak MF; Levendoglu-Tugal O; Sandoval C; Seiter K; Kajstura M; Traganos F; Jayabose S; Darzynkiewicz Z
    Cell Cycle; 2009 Jun; 8(11):1720-4. PubMed ID: 19411853
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Zinc fixation preserves flow cytometry scatter and fluorescence parameters and allows simultaneous analysis of DNA content and synthesis, and intracellular and surface epitopes.
    Jensen UB; Owens DM; Pedersen S; Christensen R
    Cytometry A; 2010 Aug; 77(8):798-804. PubMed ID: 20653019
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells.
    Li Y; Xiong H; Yang DQ
    Chin J Cancer; 2012 Aug; 31(8):364-72. PubMed ID: 22739265
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation.
    Smart DJ; Halicka HD; Traganos F; Darzynkiewicz Z; Williams GM
    Cancer Biol Ther; 2008 Jan; 7(1):113-9. PubMed ID: 18059176
    [TBL] [Abstract][Full Text] [Related]  

  • 25. AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.
    Baritaud M; Cabon L; Delavallée L; Galán-Malo P; Gilles ME; Brunelle-Navas MN; Susin SA
    Cell Death Dis; 2012 Sep; 3(9):e390. PubMed ID: 22972376
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species.
    Tanaka T; Kurose A; Halicka HD; Huang X; Traganos F; Darzynkiewicz Z
    Cell Cycle; 2006 Aug; 5(15):1669-74. PubMed ID: 16861926
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine.
    Huang X; Kurose A; Tanaka T; Traganos F; Dai W; Darzynkiewicz Z
    Cancer Biol Ther; 2006 Aug; 5(8):959-64. PubMed ID: 16760673
    [TBL] [Abstract][Full Text] [Related]  

  • 28. CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines.
    Pobst LJ; Ames MM
    Cancer Chemother Pharmacol; 2006 May; 57(5):569-76. PubMed ID: 16096788
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Induction of DNA damage response by the supravital probes of nucleic acids.
    Zhao H; Traganos F; Dobrucki J; Wlodkowic D; Darzynkiewicz Z
    Cytometry A; 2009 Jun; 75(6):510-9. PubMed ID: 19373929
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin.
    Huang X; Okafuji M; Traganos F; Luther E; Holden E; Darzynkiewicz Z
    Cytometry A; 2004 Apr; 58(2):99-110. PubMed ID: 15057963
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement.
    Tu LC; Matsui SI; Beerman TA
    Mol Cancer Ther; 2005 Aug; 4(8):1175-85. PubMed ID: 16093433
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3.
    Halicka HD; Zhao H; Li J; Traganos F; Studzinski GP; Darzynkiewicz Z
    Aging (Albany NY); 2012 Apr; 4(4):270-8. PubMed ID: 22498490
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 2-deoxy-D-glucose reduces the level of constitutive activation of ATM and phosphorylation of histone H2AX.
    Tanaka T; Kurose A; Halicka HD; Traganos F; Darzynkiewicz Z
    Cell Cycle; 2006 Apr; 5(8):878-82. PubMed ID: 16628006
    [TBL] [Abstract][Full Text] [Related]  

  • 34. ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.
    Jossé R; Martin SE; Guha R; Ormanoglu P; Pfister TD; Reaper PM; Barnes CS; Jones J; Charlton P; Pollard JR; Morris J; Doroshow JH; Pommier Y
    Cancer Res; 2014 Dec; 74(23):6968-79. PubMed ID: 25269479
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Phosphorylation of histone H2AX at M phase in human cells without DNA damage response.
    Ichijima Y; Sakasai R; Okita N; Asahina K; Mizutani S; Teraoka H
    Biochem Biophys Res Commun; 2005 Oct; 336(3):807-12. PubMed ID: 16153602
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison.
    Sakasai R; Teraoka H; Takagi M; Tibbetts RS
    J Biol Chem; 2010 May; 285(20):15201-15208. PubMed ID: 20304914
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Phosphorylation of histone H2AX on Ser 139 and activation of ATM during oxidative burst in phorbol ester-treated human leukocytes.
    Tanaka T; Halicka HD; Traganos F; Darzynkiewicz Z
    Cell Cycle; 2006 Nov; 5(22):2671-5. PubMed ID: 17106266
    [TBL] [Abstract][Full Text] [Related]  

  • 38. DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis.
    Huang X; Traganos F; Darzynkiewicz Z
    Cell Cycle; 2003; 2(6):614-9. PubMed ID: 14504478
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [gamma H2AX in the recognition of DNA double-strand breaks].
    Podhorecka M
    Postepy Hig Med Dosw (Online); 2009 Feb; 63():92-8. PubMed ID: 19252467
    [TBL] [Abstract][Full Text] [Related]  

  • 40. DNA Damage Response Resulting from Replication Stress Induced by Synchronization of Cells by Inhibitors of DNA Replication: Analysis by Flow Cytometry.
    Halicka D; Zhao H; Li J; Garcia J; Podhorecka M; Darzynkiewicz Z
    Methods Mol Biol; 2017; 1524():107-119. PubMed ID: 27815899
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.