641 related articles for article (PubMed ID: 21598254)
1. Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes.
Liu Y; Liu F; Grundke-Iqbal I; Iqbal K; Gong CX
J Pathol; 2011 Sep; 225(1):54-62. PubMed ID: 21598254
[TBL] [Abstract][Full Text] [Related]
2. Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease.
Liu Y; Liu F; Grundke-Iqbal I; Iqbal K; Gong CX
J Neurochem; 2009 Oct; 111(1):242-9. PubMed ID: 19659459
[TBL] [Abstract][Full Text] [Related]
3. Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link.
Zhang Y; Huang NQ; Yan F; Jin H; Zhou SY; Shi JS; Jin F
Behav Brain Res; 2018 Feb; 339():57-65. PubMed ID: 29158110
[TBL] [Abstract][Full Text] [Related]
4. Reduced insulin-induced phosphatidylinositol-3-kinase activation in peripheral blood mononuclear leucocytes from patients with Alzheimer's disease.
Castri P; Iacovelli L; De Blasi A; Giubilei F; Moretti A; Tari Capone F; Nicoletti F; Orzi F
Eur J Neurosci; 2007 Nov; 26(9):2469-72. PubMed ID: 17986027
[TBL] [Abstract][Full Text] [Related]
5. The rise and fall of insulin signaling in Alzheimer's disease.
Chami B; Steel AJ; De La Monte SM; Sutherland GT
Metab Brain Dis; 2016 Jun; 31(3):497-515. PubMed ID: 26883429
[TBL] [Abstract][Full Text] [Related]
6. Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes.
Yang Y; Ma D; Wang Y; Jiang T; Hu S; Zhang M; Yu X; Gong CX
J Alzheimers Dis; 2013; 33(2):329-38. PubMed ID: 22936005
[TBL] [Abstract][Full Text] [Related]
7. Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain.
Gu J; Jin N; Ma D; Chu D; Iqbal K; Gong CX; Liu F
J Alzheimers Dis; 2018; 62(4):1737-1746. PubMed ID: 29614685
[TBL] [Abstract][Full Text] [Related]
8. Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease.
Jin N; Yin X; Yu D; Cao M; Gong CX; Iqbal K; Ding F; Gu X; Liu F
Sci Rep; 2015 Feb; 5():8187. PubMed ID: 25641096
[TBL] [Abstract][Full Text] [Related]
9. Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease.
Deng Y; Li B; Liu Y; Iqbal K; Grundke-Iqbal I; Gong CX
Am J Pathol; 2009 Nov; 175(5):2089-98. PubMed ID: 19815707
[TBL] [Abstract][Full Text] [Related]
10. Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats.
Xu W; Liu J; Ma D; Yuan G; Lu Y; Yang Y
PLoS One; 2017; 12(2):e0172477. PubMed ID: 28225806
[TBL] [Abstract][Full Text] [Related]
11. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.
Kurbatskaya K; Phillips EC; Croft CL; Dentoni G; Hughes MM; Wade MA; Al-Sarraj S; Troakes C; O'Neill MJ; Perez-Nievas BG; Hanger DP; Noble W
Acta Neuropathol Commun; 2016 Mar; 4():34. PubMed ID: 27036949
[TBL] [Abstract][Full Text] [Related]
12. Cellular and Molecular Mechanisms of Dementia: Decoding the Causal link of Diabetes Mellitus in Alzheimer's Disease.
Rasool M; Malik A; Waquar S; Zaheer A; Asif M; Iqbal Z; Gauthaman K; Kamal MA; Pushparaj PN
CNS Neurol Disord Drug Targets; 2021; 20(7):602-612. PubMed ID: 33583389
[TBL] [Abstract][Full Text] [Related]
13. Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development.
Sajan M; Hansen B; Ivey R; Sajan J; Ari C; Song S; Braun U; Leitges M; Farese-Higgs M; Farese RV
Diabetes; 2016 Jul; 65(7):1892-903. PubMed ID: 26895791
[TBL] [Abstract][Full Text] [Related]
14. Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes.
Xu W; Yang Y; Yuan G; Zhu W; Ma D; Hu S
J Investig Med; 2015 Feb; 63(2):267-72. PubMed ID: 25479064
[TBL] [Abstract][Full Text] [Related]
15. Age-dependent increases in tau phosphorylation in the brains of type 2 diabetic rats correlate with a reduced expression of p62.
Jung HJ; Kim YJ; Eggert S; Chung KC; Choi KS; Park SA
Exp Neurol; 2013 Oct; 248():441-50. PubMed ID: 23906983
[TBL] [Abstract][Full Text] [Related]
16. Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes.
Yang Y; Zhang J; Ma D; Zhang M; Hu S; Shao S; Gong CX
J Alzheimers Dis; 2013; 37(3):637-48. PubMed ID: 23948890
[TBL] [Abstract][Full Text] [Related]
17. Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease.
Liu F; Shi J; Tanimukai H; Gu J; Gu J; Grundke-Iqbal I; Iqbal K; Gong CX
Brain; 2009 Jul; 132(Pt 7):1820-32. PubMed ID: 19451179
[TBL] [Abstract][Full Text] [Related]
18. Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
Imamura T; Yanagihara YT; Ohyagi Y; Nakamura N; Iinuma KM; Yamasaki R; Asai H; Maeda M; Murakami K; Irie K; Kira JI
Neurobiol Dis; 2020 Apr; 137():104739. PubMed ID: 31927145
[TBL] [Abstract][Full Text] [Related]
19. Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin.
Jolivalt CG; Lee CA; Beiswenger KK; Smith JL; Orlov M; Torrance MA; Masliah E
J Neurosci Res; 2008 Nov; 86(15):3265-74. PubMed ID: 18627032
[TBL] [Abstract][Full Text] [Related]
20. Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease.
Gratuze M; El Khoury NB; Turgeon A; Julien C; Marcouiller F; Morin F; Whittington RA; Marette A; Calon F; Planel E
Neurobiol Dis; 2017 Feb; 98():1-8. PubMed ID: 27793638
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]