These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 21599022)

  • 21. Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.
    Campiani G; Butini S; Trotta F; Fattorusso C; Catalanotti B; Aiello F; Gemma S; Nacci V; Novellino E; Stark JA; Cagnotto A; Fumagalli E; Carnovali F; Cervo L; Mennini T
    J Med Chem; 2003 Aug; 46(18):3822-39. PubMed ID: 12930145
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Functionally selective dopamine D₂, D₃ receptor partial agonists.
    Möller D; Kling RC; Skultety M; Leuner K; Hübner H; Gmeiner P
    J Med Chem; 2014 Jun; 57(11):4861-75. PubMed ID: 24831693
    [TBL] [Abstract][Full Text] [Related]  

  • 23. (S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist.
    TenBrink RE; Bergh CL; Duncan JN; Harris DW; Huff RM; Lahti RA; Lawson CF; Lutzke BS; Martin IJ; Rees SA; Schlachter SK; Sih JC; Smith MW
    J Med Chem; 1996 Jun; 39(13):2435-7. PubMed ID: 8691438
    [No Abstract]   [Full Text] [Related]  

  • 24. Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif.
    Carro L; Raviña E; Domínguez E; Brea J; Loza MI; Masaguer CF
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6059-62. PubMed ID: 19796944
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bioisosteric replacement leading to biologically active [2.2]paracyclophanes with altered binding profiles for aminergic G-protein-coupled receptors.
    Skultety M; Hübner H; Löber S; Gmeiner P
    J Med Chem; 2010 Oct; 53(19):7219-28. PubMed ID: 20839776
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
    Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and receptor binding studies of novel 4,4-disubstituted arylalkyl/arylalkylsulfonyl piperazine and piperidine-based derivatives as a new class of σ1 ligands.
    Sadeghzadeh M; Sheibani S; Ghandi M; Daha FJ; Amanlou M; Arjmand M; Hasani Bozcheloie A
    Eur J Med Chem; 2013 Jun; 64():488-97. PubMed ID: 23680866
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).
    Pettersson F; Pontén H; Waters N; Waters S; Sonesson C
    J Med Chem; 2010 Mar; 53(6):2510-20. PubMed ID: 20155917
    [TBL] [Abstract][Full Text] [Related]  

  • 29. [3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor.
    Moreland RB; Terranova MA; Chang R; Uchic ME; Matulenko MA; Surber BW; Stewart AO; Brioni JD
    Eur J Pharmacol; 2004 Aug; 497(2):147-54. PubMed ID: 15306199
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors.
    Reitz AB; Baxter EW; Codd EE; Davis CB; Jordan AD; Maryanoff BE; Maryanoff CA; McDonnell ME; Powell ET; Renzi MJ; Schott MR; Scott MK; Shank RP; Vaught JL
    J Med Chem; 1998 Jun; 41(12):1997-2009. PubMed ID: 9622541
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
    Campiani G; Butini S; Fattorusso C; Catalanotti B; Gemma S; Nacci V; Morelli E; Cagnotto A; Mereghetti I; Mennini T; Carli M; Minetti P; Di Cesare MA; Mastroianni D; Scafetta N; Galletti B; Stasi MA; Castorina M; Pacifici L; Vertechy M; Di Serio S; Ghirardi O; Tinti O; Carminati P
    J Med Chem; 2004 Jan; 47(1):143-57. PubMed ID: 14695828
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain.
    Kortagere S; Gmeiner P; Weinstein H; Schetz JA
    Mol Pharmacol; 2004 Dec; 66(6):1491-9. PubMed ID: 15448188
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D(3) receptor ligands.
    Insua I; Alvarado M; Masaguer CF; Iglesias A; Brea J; Loza MI; Carro L
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5586-91. PubMed ID: 24012118
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and dual D2 and 5-HT1A receptor binding affinities of 5-piperidinyl and 5-piperazinyl-1H-benzo[d]imidazol-2(3H)-ones.
    Ullah N
    J Enzyme Inhib Med Chem; 2014 Apr; 29(2):281-91. PubMed ID: 23488743
    [TBL] [Abstract][Full Text] [Related]  

  • 35. N-Propylnoraporphin-11-O-yl carboxylic esters as potent dopamine D(2) and serotonin 5-HT(1A) receptor dual ligands.
    Liu Z; Chen X; Sun P; Yu L; Zhen X; Zhang A
    Bioorg Med Chem; 2008 Sep; 16(18):8335-8. PubMed ID: 18783955
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists.
    Chen X; Sassano MF; Zheng L; Setola V; Chen M; Bai X; Frye SV; Wetsel WC; Roth BL; Jin J
    J Med Chem; 2012 Aug; 55(16):7141-53. PubMed ID: 22845053
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand.
    Matulenko MA; Surber B; Fan L; Kolasa T; Nakane M; Terranova MA; Uchic ME; Miller LN; Chang R; Donnelly-Roberts DL; Namovic MT; Moreland RB; Brioni JD; Stewart AO
    Bioorg Med Chem Lett; 2004 Oct; 14(20):5095-8. PubMed ID: 15380206
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis, and evaluation of chromen-2-ones as potent and selective human dopamine D4 antagonists.
    Kesten SR; Heffner TG; Johnson SJ; Pugsley TA; Wright JL; Wise LD
    J Med Chem; 1999 Sep; 42(18):3718-25. PubMed ID: 10479303
    [TBL] [Abstract][Full Text] [Related]  

  • 39. N-n-Propyl-substituted 3-(dimethylphenyl)piperidines display novel discriminative properties between dopamine receptor subtypes: synthesis and receptor binding studies.
    Cervetto L; Demontis GC; Giannaccini G; Longoni B; Macchia B; Macchia M; Martinelli A; Orlandini E
    J Med Chem; 1998 Dec; 41(25):4933-8. PubMed ID: 9836610
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 2,2-Dicyanovinyl as a nonaromatic aryl bioisostere: synthesis, binding experiments and SAR studies of highly selective dopamine D4 receptor ligands.
    Haubmann C; Hübner H; Gmeiner P
    Bioorg Med Chem Lett; 1999 Jul; 9(14):1969-72. PubMed ID: 10450964
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.