132 related articles for article (PubMed ID: 21599581)
1. The mammalian target of rapamycin pathway as a therapeutic target in multiple myeloma.
Gera J; Lichtenstein A
Leuk Lymphoma; 2011 Oct; 52(10):1857-66. PubMed ID: 21599581
[TBL] [Abstract][Full Text] [Related]
2. Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor.
Hoang B; Frost P; Shi Y; Belanger E; Benavides A; Pezeshkpour G; Cappia S; Guglielmelli T; Gera J; Lichtenstein A
Blood; 2010 Nov; 116(22):4560-8. PubMed ID: 20686120
[TBL] [Abstract][Full Text] [Related]
3. Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.
Shi Y; Daniels-Wells TR; Frost P; Lee J; Finn RS; Bardeleben C; Penichet ML; Jung ME; Gera J; Lichtenstein A
Cancer Res; 2016 Oct; 76(19):5822-5831. PubMed ID: 27530328
[TBL] [Abstract][Full Text] [Related]
4. The mTOR signaling pathway is an emerging therapeutic target in multiple myeloma.
Li J; Zhu J; Cao B; Mao X
Curr Pharm Des; 2014; 20(1):125-35. PubMed ID: 24001224
[TBL] [Abstract][Full Text] [Related]
5. New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).
Feldman ME; Shokat KM
Curr Top Microbiol Immunol; 2010; 347():241-62. PubMed ID: 20549474
[TBL] [Abstract][Full Text] [Related]
6. Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin.
Yu K; Toral-Barza L; Shi C; Zhang WG; Lucas J; Shor B; Kim J; Verheijen J; Curran K; Malwitz DJ; Cole DC; Ellingboe J; Ayral-Kaloustian S; Mansour TS; Gibbons JJ; Abraham RT; Nowak P; Zask A
Cancer Res; 2009 Aug; 69(15):6232-40. PubMed ID: 19584280
[TBL] [Abstract][Full Text] [Related]
7. Target of rapamycin signaling in leukemia and lymphoma.
Vu C; Fruman DA
Clin Cancer Res; 2010 Nov; 16(22):5374-80. PubMed ID: 20826559
[TBL] [Abstract][Full Text] [Related]
8. [m-TOR inhibitors: biology and use in the treatment of haematological diseases].
Balsat M; Cornillon J
Bull Cancer; 2011 Aug; 98(8):935-43. PubMed ID: 21827982
[TBL] [Abstract][Full Text] [Related]
9. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Desantis A; Bruno T; Catena V; De Nicola F; Goeman F; Iezzi S; Sorino C; Ponzoni M; Bossi G; Federico V; La Rosa F; Ricciardi MR; Lesma E; De Meo PD; Castrignanò T; Petrucci MT; Pisani F; Chesi M; Bergsagel PL; Floridi A; Tonon G; Passananti C; Blandino G; Fanciulli M
EMBO J; 2015 May; 34(9):1214-30. PubMed ID: 25770584
[TBL] [Abstract][Full Text] [Related]
10. Knockdown of DEPTOR induces apoptosis, increases chemosensitivity to doxorubicin and suppresses autophagy in RPMI-8226 human multiple myeloma cells in vitro.
Zhang H; Chen J; Zeng Z; Que W; Zhou L
Int J Mol Med; 2013 May; 31(5):1127-34. PubMed ID: 23503641
[TBL] [Abstract][Full Text] [Related]
11. Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability.
Xue Q; Hopkins B; Perruzzi C; Udayakumar D; Sherris D; Benjamin LE
Cancer Res; 2008 Nov; 68(22):9551-7. PubMed ID: 19010932
[TBL] [Abstract][Full Text] [Related]
12. Role of TSC-mTOR pathway in diabetic nephropathy.
Inoki K
Diabetes Res Clin Pract; 2008 Nov; 82 Suppl 1():S59-62. PubMed ID: 18926585
[TBL] [Abstract][Full Text] [Related]
13. Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779.
Shi Y; Gera J; Hu L; Hsu JH; Bookstein R; Li W; Lichtenstein A
Cancer Res; 2002 Sep; 62(17):5027-34. PubMed ID: 12208757
[TBL] [Abstract][Full Text] [Related]
14. mTOR-what does it do?
Hall MN
Transplant Proc; 2008 Dec; 40(10 Suppl):S5-8. PubMed ID: 19100909
[TBL] [Abstract][Full Text] [Related]
15. Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Martelli AM; Evangelisti C; Chappell W; Abrams SL; Bäsecke J; Stivala F; Donia M; Fagone P; Nicoletti F; Libra M; Ruvolo V; Ruvolo P; Kempf CR; Steelman LS; McCubrey JA
Leukemia; 2011 Jul; 25(7):1064-79. PubMed ID: 21436840
[TBL] [Abstract][Full Text] [Related]
16. AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.
Frost P; Shi Y; Hoang B; Lichtenstein A
Oncogene; 2007 Apr; 26(16):2255-62. PubMed ID: 17016437
[TBL] [Abstract][Full Text] [Related]
17. mTOR Signalling in Health and Disease.
Proud CG
Biochem Soc Trans; 2011 Apr; 39(2):431-6. PubMed ID: 21428914
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR.
Chen SM; Liu JL; Wang X; Liang C; Ding J; Meng LH
Biochem Pharmacol; 2012 May; 83(9):1183-94. PubMed ID: 22305748
[TBL] [Abstract][Full Text] [Related]
19. The evolution of the TOR pathway and its role in cancer.
Beauchamp EM; Platanias LC
Oncogene; 2013 Aug; 32(34):3923-32. PubMed ID: 23246968
[TBL] [Abstract][Full Text] [Related]
20. TORC2 Structure and Function.
Gaubitz C; Prouteau M; Kusmider B; Loewith R
Trends Biochem Sci; 2016 Jun; 41(6):532-545. PubMed ID: 27161823
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]