BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 21602279)

  • 1. Random mutagenesis of the proton-coupled folate transporter (SLC46A1), clustering of mutations, and the bases for associated losses of function.
    Zhao R; Shin DS; Diop-Bove N; Ovits CG; Goldman ID
    J Biol Chem; 2011 Jul; 286(27):24150-8. PubMed ID: 21602279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption.
    Shin DS; Mahadeo K; Min SH; Diop-Bove N; Clayton P; Zhao R; Goldman ID
    Mol Genet Metab; 2011 May; 103(1):33-7. PubMed ID: 21333572
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption.
    Shin DS; Zhao R; Fiser A; Goldman DI
    Am J Physiol Cell Physiol; 2012 Oct; 303(8):C834-42. PubMed ID: 22843796
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation.
    Zhan HQ; Najmi M; Lin K; Aluri S; Fiser A; Goldman ID; Zhao R
    J Biol Chem; 2020 Nov; 295(46):15650-15661. PubMed ID: 32893190
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption.
    Mahadeo K; Diop-Bove N; Shin D; Unal ES; Teo J; Zhao R; Chang MH; Fulterer A; Romero MF; Goldman ID
    Am J Physiol Cell Physiol; 2010 Nov; 299(5):C1153-61. PubMed ID: 20686069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel deletion mutation in the proton-coupled folate transporter (PCFT; SLC46A1) in a Nicaraguan child with hereditary folate malabsorption.
    Diop-Bove N; Jain M; Scaglia F; Goldman ID
    Gene; 2013 Sep; 527(2):673-4. PubMed ID: 23816405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of Tyr residues that enhance folate substrate binding and constrain oscillation of the proton-coupled folate transporter (PCFT-SLC46A1).
    Visentin M; Unal ES; Najmi M; Fiser A; Zhao R; Goldman ID
    Am J Physiol Cell Physiol; 2015 Apr; 308(8):C631-41. PubMed ID: 25608532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.
    Zhao R; Aluri S; Goldman ID
    Mol Aspects Med; 2017 Feb; 53():57-72. PubMed ID: 27664775
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of the tryptophan residues in proton-coupled folate transporter (PCFT-SLC46A1) function.
    Najmi M; Zhao R; Fiser A; Goldman ID
    Am J Physiol Cell Physiol; 2016 Jul; 311(1):C150-7. PubMed ID: 27251438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation of the proton-coupled folate transporter gene (PCFT-SLC46A1) in Turkish siblings with hereditary folate malabsorption.
    Atabay B; Turker M; Ozer EA; Mahadeo K; Diop-Bove N; Goldman ID
    Pediatr Hematol Oncol; 2010 Nov; 27(8):614-9. PubMed ID: 20795774
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1.
    Aluri S; Zhao R; Lubout C; Goorden SMI; Fiser A; Goldman ID
    Blood Adv; 2018 Jan; 2(1):61-68. PubMed ID: 29344585
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding.
    Shin DS; Zhao R; Yap EH; Fiser A; Goldman ID
    Am J Physiol Cell Physiol; 2012 May; 302(9):C1405-12. PubMed ID: 22345511
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A deep intronic mutation of c.1166-285 T > G in SLC46A1 is shared by four unrelated Japanese patients with hereditary folate malabsorption (HFM).
    Tozawa Y; Abdrabou SSMA; Nogawa-Chida N; Nishiuchi R; Ishida T; Suzuki Y; Sano H; Kobayashi R; Kishimoto K; Ohara O; Imai K; Naruto T; Kobayashi K; Ariga T; Yamada M
    Clin Immunol; 2019 Nov; 208():108256. PubMed ID: 31494288
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1.
    Unal ES; Zhao R; Goldman ID
    Am J Physiol Cell Physiol; 2009 Jul; 297(1):C66-74. PubMed ID: 19403800
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation.
    Aluri S; Zhao R; Lin K; Shin DS; Fiser A; Goldman ID
    J Biol Chem; 2019 May; 294(18):7245-7258. PubMed ID: 30858177
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption.
    Zhao R; Min SH; Qiu A; Sakaris A; Goldberg GL; Sandoval C; Malatack JJ; Rosenblatt DS; Goldman ID
    Blood; 2007 Aug; 110(4):1147-52. PubMed ID: 17446347
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method.
    Shin DS; Zhao R; Fiser A; Goldman ID
    Am J Physiol Cell Physiol; 2013 Jun; 304(12):C1159-67. PubMed ID: 23552283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biology of the major facilitative folate transporters SLC19A1 and SLC46A1.
    Hou Z; Matherly LH
    Curr Top Membr; 2014; 73():175-204. PubMed ID: 24745983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method.
    Zhao R; Shin DS; Goldman ID
    Biochim Biophys Acta; 2011 Apr; 1808(4):1140-5. PubMed ID: 21256110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis.
    Zhao R; Min SH; Wang Y; Campanella E; Low PS; Goldman ID
    J Biol Chem; 2009 Feb; 284(7):4267-74. PubMed ID: 19074442
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.