These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 21602883)

  • 1. Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression.
    Lushnikova T; Bouska A; Odvody J; Dupont WD; Eischen CM
    Oncogene; 2011 Nov; 30(46):4622-31. PubMed ID: 21602883
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells.
    Wang P; Lushnikova T; Odvody J; Greiner TC; Jones SN; Eischen CM
    Oncogene; 2008 Mar; 27(11):1590-8. PubMed ID: 17828300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mdm2 promotes genetic instability and transformation independent of p53.
    Bouska A; Lushnikova T; Plaza S; Eischen CM
    Mol Cell Biol; 2008 Aug; 28(15):4862-74. PubMed ID: 18541670
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma.
    Riley MF; You MJ; Multani AS; Lozano G
    Oncogene; 2016 Jan; 35(3):358-65. PubMed ID: 25915849
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms and consequences of aneuploidy and chromosome instability in the aging brain.
    Andriani GA; Vijg J; Montagna C
    Mech Ageing Dev; 2017 Jan; 161(Pt A):19-36. PubMed ID: 27013377
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Murine double minute 2: p53-independent roads lead to genome instability or death.
    Bouska A; Eischen CM
    Trends Biochem Sci; 2009 Jun; 34(6):279-86. PubMed ID: 19447627
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The MDM2-a splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf- and p53-null models of tumorigenesis.
    Volk EL; Fan L; Schuster K; Rehg JE; Harris LC
    Mol Cancer Res; 2009 Jun; 7(6):863-9. PubMed ID: 19491200
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells.
    Carrillo AM; Hicks M; Khabele D; Eischen CM
    Mol Cancer Res; 2015 Aug; 13(8):1197-205. PubMed ID: 25964101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Emerging links among Chromosome Instability (CIN), cancer, and aging.
    Rao CV; Asch AS; Yamada HY
    Mol Carcinog; 2017 Mar; 56(3):791-803. PubMed ID: 27533343
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence.
    Volk EL; Schuster K; Nemeth KM; Fan L; Harris LC
    Dis Model Mech; 2009; 2(1-2):47-55. PubMed ID: 19132120
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation.
    Malek R; Matta J; Taylor N; Perry ME; Mendrysa SM
    PLoS One; 2011 Mar; 6(3):e17884. PubMed ID: 21437245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability.
    Chen M; Huang JD; Deng HK; Dong S; Deng W; Tsang SL; Huen MS; Chen L; Zan T; Zhu GX; Guan XY
    BMC Cancer; 2011 May; 11():199. PubMed ID: 21612665
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chromosomal instability suppresses the growth of K-Ras-induced lung adenomas.
    Laucius CD; Orr B; Compton DA
    Cell Cycle; 2019 Aug; 18(15):1702-1713. PubMed ID: 31179849
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
    Padilla-Nash HM; Hathcock K; McNeil NE; Mack D; Hoeppner D; Ravin R; Knutsen T; Yonescu R; Wangsa D; Dorritie K; Barenboim L; Hu Y; Ried T
    Genes Chromosomes Cancer; 2012 Apr; 51(4):353-74. PubMed ID: 22161874
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mdm2 affects genome stability independent of p53.
    Bouska A; Eischen CM
    Cancer Res; 2009 Mar; 69(5):1697-701. PubMed ID: 19244108
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice.
    Teoh NC; Dan YY; Swisshelm K; Lehman S; Wright JH; Haque J; Gu Y; Fausto N
    Hepatology; 2008 Jun; 47(6):2078-88. PubMed ID: 18506893
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
    Eischen CM; Boyd K
    PLoS One; 2012; 7(9):e46148. PubMed ID: 23029416
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transient genomic instability drives tumorigenesis through accelerated clonal evolution.
    Shoshani O; Bakker B; de Haan L; Tijhuis AE; Wang Y; Kim DH; Maldonado M; Demarest MA; Artates J; Zhengyu O; Mark A; Wardenaar R; Sasik R; Spierings DCJ; Vitre B; Fisch K; Foijer F; Cleveland DW
    Genes Dev; 2021 Aug; 35(15-16):1093-1108. PubMed ID: 34266887
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells.
    Slack AD; Chen Z; Ludwig AD; Hicks J; Shohet JM
    Cancer Res; 2007 Mar; 67(6):2448-55. PubMed ID: 17363562
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct patterns of structural and numerical chromosomal instability characterize sporadic ovarian cancer.
    Bayani J; Paderova J; Murphy J; Rosen B; Zielenska M; Squire JA
    Neoplasia; 2008 Oct; 10(10):1057-65. PubMed ID: 18813350
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.