194 related articles for article (PubMed ID: 21604746)
1. Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4.
Fortin S; Wei L; Moreau E; Lacroix J; Côté MF; Petitclerc E; Kotra LP; C-Gaudreault R
J Med Chem; 2011 Jul; 54(13):4559-80. PubMed ID: 21604746
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.
Bouzriba C; Gagné-Boulet M; Chavez Alvarez AC; Ouellette V; Laverdière I; Fortin S
Bioorg Chem; 2024 May; 146():107299. PubMed ID: 38547722
[TBL] [Abstract][Full Text] [Related]
3. Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships.
Fortin S; Wei L; Moreau E; Lacroix J; Côté MF; Petitclerc E; Kotra LP; Gaudreault RC
Eur J Med Chem; 2011 Nov; 46(11):5327-42. PubMed ID: 21920638
[TBL] [Abstract][Full Text] [Related]
4. Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
Gagné-Boulet M; Bouzriba C; Chavez Alvarez AC; Fortin S
Eur J Med Chem; 2021 Mar; 213():113136. PubMed ID: 33472119
[TBL] [Abstract][Full Text] [Related]
5. Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Ouellette V; Bouzriba C; Chavez Alvarez AC; Hamel-Côté G; Fortin S
Bioorg Med Chem Lett; 2024 Jun; 105():129745. PubMed ID: 38614151
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, biological evaluation, and structure-activity relationships of novel substituted N-phenyl ureidobenzenesulfonate derivatives blocking cell cycle progression in S-phase and inducing DNA double-strand breaks.
Turcotte V; Fortin S; Vevey F; Coulombe Y; Lacroix J; Côté MF; Masson JY; C-Gaudreault R
J Med Chem; 2012 Jul; 55(13):6194-208. PubMed ID: 22694057
[TBL] [Abstract][Full Text] [Related]
7. Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.
Gagné-Boulet M; Bouzriba C; Chavez Alvarez AC; Fortin S
Chem Biol Drug Des; 2022 Feb; 99(2):187-196. PubMed ID: 34623027
[TBL] [Abstract][Full Text] [Related]
8. 4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles that are cytotoxic against combretastatin A resistant tumor cells and vascular disrupting in a cisplatin resistant germ cell tumor model.
Schobert R; Biersack B; Dietrich A; Effenberger K; Knauer S; Mueller T
J Med Chem; 2010 Sep; 53(18):6595-602. PubMed ID: 20731355
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1.
Akselsen OW; Odlo K; Cheng JJ; Maccari G; Botta M; Hansen TV
Bioorg Med Chem; 2012 Jan; 20(1):234-42. PubMed ID: 22137934
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
12. Styryl-N-phenyl-N'-(2-chloroethyl)ureas and styrylphenylimidazolidin-2-ones as new potent microtubule-disrupting agents using combretastatin A-4 as model.
Gagné-Boulet M; Fortin S; Lacroix J; Lefebvre CA; Côté MF; C-Gaudreault R
Eur J Med Chem; 2015 Jul; 100():34-43. PubMed ID: 26069928
[TBL] [Abstract][Full Text] [Related]
13. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
Barnes NG; Parker AW; Ahmed Mal Ullah AA; Ragazzon PA; Hadfield JA
Bioorg Med Chem; 2020 Oct; 28(19):115684. PubMed ID: 32912434
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Wang F; Yang Z; Liu Y; Ma L; Wu Y; He L; Shao M; Yu K; Wu W; Pu Y; Nie C; Chen L
Bioorg Med Chem; 2015 Jul; 23(13):3337-50. PubMed ID: 25937236
[TBL] [Abstract][Full Text] [Related]
15. New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
De Martino G; Edler MC; La Regina G; Coluccia A; Barbera MC; Barrow D; Nicholson RI; Chiosis G; Brancale A; Hamel E; Artico M; Silvestri R
J Med Chem; 2006 Feb; 49(3):947-54. PubMed ID: 16451061
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
[TBL] [Abstract][Full Text] [Related]
17. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
[TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
Nakamura M; Kajita D; Matsumoto Y; Hashimoto Y
Bioorg Med Chem; 2013 Dec; 21(23):7381-91. PubMed ID: 24139940
[TBL] [Abstract][Full Text] [Related]
19. Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation.
Bouzriba C; Chavez Alvarez AC; Gagné-Boulet M; Ouellette V; Lacroix J; Côté MF; C-Gaudreault R; Fortin S
Eur J Med Chem; 2022 Feb; 229():114003. PubMed ID: 34839998
[TBL] [Abstract][Full Text] [Related]
20. Optimization of antiproliferative activity of substituted phenyl 4-(2-oxoimidazolidin-1-yl) benzenesulfonates: QSAR and CoMFA analyses.
Masand VH; Mahajan DT; Alafeefy AM; Bukhari SN; Elsayed NN
Eur J Pharm Sci; 2015 Sep; 77():230-7. PubMed ID: 26066412
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
