BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 21608133)

  • 1. Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates.
    Wood PM; Woo LW; Thomas MP; Mahon MF; Purohit A; Potter BV
    ChemMedChem; 2011 Aug; 6(8):1423-38. PubMed ID: 21608133
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity.
    Wood PM; Woo LW; Labrosse JR; Trusselle MN; Abbate S; Longhi G; Castiglioni E; Lebon F; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2008 Jul; 51(14):4226-38. PubMed ID: 18590272
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activities.
    Wood PM; Woo LW; Labrosse JR; Thomas MP; Mahon MF; Chander SK; Purohit A; Reed MJ; Potter BV
    ChemMedChem; 2010 Sep; 5(9):1577-93. PubMed ID: 20632362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activities.
    Bubert C; Woo LW; Sutcliffe OB; Mahon MF; Chander SK; Purohit A; Reed MJ; Potter BV
    ChemMedChem; 2008 Nov; 3(11):1708-30. PubMed ID: 18816537
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
    Woo LW; Jackson T; Putey A; Cozier G; Leonard P; Acharya KR; Chander SK; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2010 Mar; 53(5):2155-70. PubMed ID: 20148564
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual aromatase-steroid sulfatase inhibitors.
    Woo LW; Bubert C; Sutcliffe OB; Smith A; Chander SK; Mahon MF; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2007 Jul; 50(15):3540-60. PubMed ID: 17580845
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure-activity relationship studies of derivatives of the dual aromatase-sulfatase inhibitor 4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate.
    Woo LW; Wood PM; Bubert C; Thomas MP; Purohit A; Potter BV
    ChemMedChem; 2013 May; 8(5):779-99. PubMed ID: 23495205
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of carbon-11-labeled dual aromatase-steroid sulfatase inhibitors as new potential PET agents for imaging of aromatase and steroid sulfatase expression in breast cancer.
    Wang M; Mickens J; Gao M; Miller KD; Sledge GW; Hutchins GD; Zheng QH
    Steroids; 2009 Nov; 74(12):896-905. PubMed ID: 19559719
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.
    Jackson T; Woo LW; Trusselle MN; Chander SK; Purohit A; Reed MJ; Potter BV
    Org Biomol Chem; 2007 Sep; 5(18):2940-52. PubMed ID: 17728860
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.
    Jackson T; Woo LW; Trusselle MN; Chander SK; Purohit A; Reed MJ; Potter BV
    Org Biomol Chem; 2007 Oct; 5(20):2940-52. PubMed ID: 17972413
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity.
    Wood PM; Woo LW; Humphreys A; Chander SK; Purohit A; Reed MJ; Potter BV
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):123-30. PubMed ID: 15862957
    [TBL] [Abstract][Full Text] [Related]  

  • 12. First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.
    Lloyd MD; Thiyagarajan N; Ho YT; Woo LW; Sutcliffe OB; Purohit A; Reed MJ; Acharya KR; Potter BV
    Biochemistry; 2005 May; 44(18):6858-66. PubMed ID: 15865431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Determination of the absolute configuration of aromatase and dual aromatase-sulfatase inhibitors by vibrational and electronic circular dichroism spectra analysis.
    Abbate S; Longhi G; Castiglioni E; Lebon F; Wood PM; Woo LW; Potter BV
    Chirality; 2009 Oct; 21(9):802-8. PubMed ID: 19161217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual aromatase-steroid sulfatase inhibitors (DASI's) for the treatment of breast cancer: a structure guided ligand based designing approach.
    Singh Y; Jaswal S; Singh S; Verma SK; Thareja S
    J Biomol Struct Dyn; 2023 Dec; 41(20):10604-10626. PubMed ID: 36510679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors.
    Doiron J; Soultan AH; Richard R; Touré MM; Picot N; Richard R; Cuperlović-Culf M; Robichaud GA; Touaibia M
    Eur J Med Chem; 2011 Sep; 46(9):4010-24. PubMed ID: 21703734
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor.
    Foster PA; Chander SK; Newman SP; Woo LW; Sutcliffe OB; Bubert C; Zhou D; Chen S; Potter BV; Reed MJ; Purohit A
    Clin Cancer Res; 2008 Oct; 14(20):6469-77. PubMed ID: 18927286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New potent STS inhibitors based on fluorinated 4-(1-phenyl-1
    Daśko M; Demkowicz S; Rachon J; Biernacki K; Aszyk J; Kozak W; Masłyk M; Kubiński K
    J Asian Nat Prod Res; 2020 Nov; 22(11):1037-1044. PubMed ID: 31773975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of steroid sulfatase inhibitors.
    Woo LW; Purohit A; Potter BV
    Mol Cell Endocrinol; 2011 Jul; 340(2):175-85. PubMed ID: 21238537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1
    Ciupak O; Daśko M; Biernacki K; Rachon J; Masłyk M; Kubiński K; Martyna A; Demkowicz S
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):238-247. PubMed ID: 33322953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors.
    Moi D; Foster PA; Rimmer LG; Jaffri A; Deplano A; Balboni G; Onnis V; Potter BVL
    Eur J Med Chem; 2019 Nov; 182():111614. PubMed ID: 31422224
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.