BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 21609739)

  • 1. Integrating molecular dynamics and co-evolutionary analysis for reliable target prediction and deregulation of the allosteric inhibition of aspartokinase for amino acid production.
    Chen Z; Rappert S; Sun J; Zeng AP
    J Biotechnol; 2011 Jul; 154(4):248-54. PubMed ID: 21609739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coevolutionary analysis enabled rational deregulation of allosteric enzyme inhibition in Corynebacterium glutamicum for lysine production.
    Chen Z; Meyer W; Rappert S; Sun J; Zeng AP
    Appl Environ Microbiol; 2011 Jul; 77(13):4352-60. PubMed ID: 21531824
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Analysis of key enzyme activities involved in aspartate amino acid biosynthesis in Streptococcus bovis].
    Kal'cheva EO; Shanskaia VO; Maliuta SS
    Biokhimiia; 1994 Jan; 59(1):96-101. PubMed ID: 8117840
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proceedings: Organization of Escherichia coli aspartokinase I-Homoserine dehydrogenase I, an allosteric enzyme. -- Its possible origin by gene fusion and its evolutionary relationship with enzymes of the same biochemical pathway.
    Cohen GN
    Hoppe Seylers Z Physiol Chem; 1975 Mar; 356(3):224-5. PubMed ID: 1102410
    [No Abstract]   [Full Text] [Related]  

  • 5. Mutation analysis of the feedback inhibition site of aspartokinase III of Escherichia coli K-12 and its use in L-threonine production.
    Ogawa-Miyata Y; Kojima H; Sano K
    Biosci Biotechnol Biochem; 2001 May; 65(5):1149-54. PubMed ID: 11440130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutational analysis of the feedback sites of lysine-sensitive aspartokinase of Escherichia coli.
    Kikuchi Y; Kojima H; Tanaka T
    FEMS Microbiol Lett; 1999 Apr; 173(1):211-5. PubMed ID: 10220897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring signal transduction in heteromultimeric protein based on energy dissipation model.
    Ma CW; Xiu ZL; Zeng AP
    J Biomol Struct Dyn; 2015; 33(1):134-46. PubMed ID: 24279729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of serine 352 in the allosteric response of Serratia marcescens aspartokinase I-homoserine dehydrogenase I analyzed by using site-directed mutagenesis.
    Omori K; Komatsubara S
    J Bacteriol; 1993 Feb; 175(4):959-65. PubMed ID: 8432719
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A new concept to reveal protein dynamics based on energy dissipation.
    Ma CW; Xiu ZL; Zeng AP
    PLoS One; 2011; 6(10):e26453. PubMed ID: 22022616
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations that cause threonine sensitivity identify catalytic and regulatory regions of the aspartate kinase of Saccharomyces cerevisiae.
    Arévalo-Rodríguez M; Calderón IL; Holmberg S
    Yeast; 1999 Sep; 15(13):1331-45. PubMed ID: 10509015
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Effect of amino acids on the beta-aspartokinase activity from Corynebacterium glutamicum of wild and mutant strains].
    Kara-murza SN; Ivanovskaia LV; Zhdanova NI
    Prikl Biokhim Mikrobiol; 1978; 14(3):345-53. PubMed ID: 209438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolically engineered soybean seed with enhanced threonine levels: biochemical characterization and seed-specific expression of lysine-insensitive variants of aspartate kinases from the enteric bacterium Xenorhabdus bovienii.
    Qi Q; Huang J; Crowley J; Ruschke L; Goldman BS; Wen L; Rapp WD
    Plant Biotechnol J; 2011 Feb; 9(2):193-204. PubMed ID: 20633240
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of intramolecular signal transduction network based on a new protein dynamics model of energy dissipation.
    Ma CW; Xiu ZL; Zeng AP
    PLoS One; 2012; 7(2):e31529. PubMed ID: 22363664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine.
    Kotaka M; Ren J; Lockyer M; Hawkins AR; Stammers DK
    J Biol Chem; 2006 Oct; 281(42):31544-52. PubMed ID: 16905770
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Effect of aspartate amino acids on aspartokinase activity of oligotrophic bacteria].
    Stepanovich TV; Nikitin DI
    Mikrobiologiia; 1985; 54(1):162-3. PubMed ID: 2989663
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of Loss-of-Function Mutants in Aspartate Kinase and Homoserine Dehydrogenase Genes Points to Complexity in the Regulation of Aspartate-Derived Amino Acid Contents.
    Clark TJ; Lu Y
    Plant Physiol; 2015 Aug; 168(4):1512-26. PubMed ID: 26063505
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploring the molecular basis for selective binding of Mycobacterium tuberculosis Asp kinase toward its natural substrates and feedback inhibitors: a docking and molecular dynamics study.
    Chaitanya M; Babajan B; Anuradha CM; Naveen M; Rajasekhar C; Madhusudana P; Kumar CS
    J Mol Model; 2010 Aug; 16(8):1357-67. PubMed ID: 20140471
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Specificity of aspartokinase III from Escherichia coli and an examination of important catalytic residues.
    Keng YF; Viola RE
    Arch Biochem Biophys; 1996 Nov; 335(1):73-81. PubMed ID: 8914836
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of aspartate in Mycobacterium smegmatis.
    Sritharan V; Wheeler PR; Ratledge C
    Eur J Biochem; 1989 Apr; 180(3):587-93. PubMed ID: 2496980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isolation of regulatory mutants of Pseudomonas acidovorans by use of amino acid analogs.
    Thevenet NJ; Vandecasteele JP
    Arch Microbiol; 1976 Mar; 107(2):225-7. PubMed ID: 1259520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.