BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

411 related articles for article (PubMed ID: 21612988)

  • 1. Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease.
    Gregg SQ; Robinson AR; Niedernhofer LJ
    DNA Repair (Amst); 2011 Jul; 10(7):781-91. PubMed ID: 21612988
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ERCC1 and ERCC4 (XPF) genes and gene products.
    Manandhar M; Boulware KS; Wood RD
    Gene; 2015 Sep; 569(2):153-61. PubMed ID: 26074087
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients.
    Ahmad A; Enzlin JH; Bhagwat NR; Wijgers N; Raams A; Appledoorn E; Theil AF; J Hoeijmakers JH; Vermeulen W; J Jaspers NG; Schärer OD; Niedernhofer LJ
    PLoS Genet; 2010 Mar; 6(3):e1000871. PubMed ID: 20221251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy.
    McNeil EM; Melton DW
    Nucleic Acids Res; 2012 Nov; 40(20):9990-10004. PubMed ID: 22941649
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interstrand crosslink repair: can XPF-ERCC1 be let off the hook?
    Bergstralh DT; Sekelsky J
    Trends Genet; 2008 Feb; 24(2):70-6. PubMed ID: 18192062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure.
    Jaspers NG; Raams A; Silengo MC; Wijgers N; Niedernhofer LJ; Robinson AR; Giglia-Mari G; Hoogstraten D; Kleijer WJ; Hoeijmakers JH; Vermeulen W
    Am J Hum Genet; 2007 Mar; 80(3):457-66. PubMed ID: 17273966
    [TBL] [Abstract][Full Text] [Related]  

  • 7. XPF knockout via CRISPR/Cas9 reveals that ERCC1 is retained in the cytoplasm without its heterodimer partner XPF.
    Lehmann J; Seebode C; Smolorz S; Schubert S; Emmert S
    Cell Mol Life Sci; 2017 Jun; 74(11):2081-2094. PubMed ID: 28130555
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex.
    Faridounnia M; Wienk H; Kovačič L; Folkers GE; Jaspers NG; Kaptein R; Hoeijmakers JH; Boelens R
    J Biol Chem; 2015 Aug; 290(33):20541-55. PubMed ID: 26085086
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs.
    Kirschner K; Melton DW
    Anticancer Res; 2010 Sep; 30(9):3223-32. PubMed ID: 20944091
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mapping of interaction domains between human repair proteins ERCC1 and XPF.
    de Laat WL; Sijbers AM; Odijk H; Jaspers NG; Hoeijmakers JH
    Nucleic Acids Res; 1998 Sep; 26(18):4146-52. PubMed ID: 9722633
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance.
    McNeil EM; Astell KR; Ritchie AM; Shave S; Houston DR; Bakrania P; Jones HM; Khurana P; Wallace C; Chapman T; Wear MA; Walkinshaw MD; Saxty B; Melton DW
    DNA Repair (Amst); 2015 Jul; 31():19-28. PubMed ID: 25956741
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders.
    Marín M; Ramírez MJ; Carmona MA; Jia N; Ogi T; Bogliolo M; Surrallés J
    Genes (Basel); 2019 Jan; 10(1):. PubMed ID: 30658521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks.
    Niedernhofer LJ; Odijk H; Budzowska M; van Drunen E; Maas A; Theil AF; de Wit J; Jaspers NG; Beverloo HB; Hoeijmakers JH; Kanaar R
    Mol Cell Biol; 2004 Jul; 24(13):5776-87. PubMed ID: 15199134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.
    Orelli B; McClendon TB; Tsodikov OV; Ellenberger T; Niedernhofer LJ; Schärer OD
    J Biol Chem; 2010 Feb; 285(6):3705-3712. PubMed ID: 19940136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Removal of reactive oxygen species-induced 3'-blocked ends by XPF-ERCC1.
    Fisher LA; Samson L; Bessho T
    Chem Res Toxicol; 2011 Nov; 24(11):1876-81. PubMed ID: 22007867
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation.
    Jones M; Beuron F; Borg A; Nans A; Earl CP; Briggs DC; Snijders AP; Bowles M; Morris EP; Linch M; McDonald NQ
    Nat Commun; 2020 Feb; 11(1):1120. PubMed ID: 32111838
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation.
    Wang J; He H; Chen B; Jiang G; Cao L; Jiang H; Zhang G; Chen J; Huang J; Yang B; Zhou C; Liu T
    Nat Commun; 2020 Feb; 11(1):786. PubMed ID: 32034146
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells.
    Lan L; Hayashi T; Rabeya RM; Nakajima S; Kanno Si; Takao M; Matsunaga T; Yoshino M; Ichikawa M; Riele Ht; Tsuchiya S; Tanaka K; Yasui A
    DNA Repair (Amst); 2004 Feb; 3(2):135-43. PubMed ID: 14706347
    [TBL] [Abstract][Full Text] [Related]  

  • 19. USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.
    Perez-Oliva AB; Lachaud C; Szyniarowski P; Muñoz I; Macartney T; Hickson I; Rouse J; Alessi DR
    EMBO J; 2015 Feb; 34(3):326-43. PubMed ID: 25538220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes.
    Zhu XD; Niedernhofer L; Kuster B; Mann M; Hoeijmakers JH; de Lange T
    Mol Cell; 2003 Dec; 12(6):1489-98. PubMed ID: 14690602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.