278 related articles for article (PubMed ID: 21619594)
1. Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel.
Garner KM; Eastman A
BMC Cancer; 2011 May; 11():206:1-13. PubMed ID: 21619594
[TBL] [Abstract][Full Text] [Related]
2. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
3. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity.
Mirzoeva OK; Kawaguchi T; Pieper RO
Mol Cancer Ther; 2006 Nov; 5(11):2757-66. PubMed ID: 17121922
[TBL] [Abstract][Full Text] [Related]
4. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.
Robison JG; Elliott J; Dixon K; Oakley GG
J Biol Chem; 2004 Aug; 279(33):34802-10. PubMed ID: 15180989
[TBL] [Abstract][Full Text] [Related]
5. Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene.
Bartkova J; Tommiska J; Oplustilova L; Aaltonen K; Tamminen A; Heikkinen T; Mistrik M; Aittomäki K; Blomqvist C; Heikkilä P; Lukas J; Nevanlinna H; Bartek J
Mol Oncol; 2008 Dec; 2(4):296-316. PubMed ID: 19383352
[TBL] [Abstract][Full Text] [Related]
6. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
7. Deletion of NAD(P)H:quinone oxidoreductase 1 represses Mre11-Rad50-Nbs1 complex protein expression in cisplatin-induced nephrotoxicity.
Kim YJ; Kim TW; Park SR; Kim HT; Jung DY; Ryu SY; Jung JY
Toxicol Lett; 2016 Jan; 243():22-30. PubMed ID: 26723870
[TBL] [Abstract][Full Text] [Related]
8. Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres.
Zhong ZH; Jiang WQ; Cesare AJ; Neumann AA; Wadhwa R; Reddel RR
J Biol Chem; 2007 Oct; 282(40):29314-22. PubMed ID: 17693401
[TBL] [Abstract][Full Text] [Related]
9. The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.
Lee AY; Liu E; Wu X
J Biol Chem; 2007 Nov; 282(44):32243-55. PubMed ID: 17715134
[TBL] [Abstract][Full Text] [Related]
10. The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.
Olson E; Nievera CJ; Lee AY; Chen L; Wu X
J Biol Chem; 2007 Aug; 282(31):22939-52. PubMed ID: 17526493
[TBL] [Abstract][Full Text] [Related]
11. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer.
Brandt S; Samartzis EP; Zimmermann AK; Fink D; Moch H; Noske A; Dedes KJ
BMC Cancer; 2017 Jan; 17(1):44. PubMed ID: 28073364
[TBL] [Abstract][Full Text] [Related]
12. Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis.
Ho V; Chung L; Singh A; Lea V; Abubakar A; Lim SH; Ng W; Lee M; de Souza P; Shin JS; Lee CS
BMC Cancer; 2018 Sep; 18(1):869. PubMed ID: 30176843
[TBL] [Abstract][Full Text] [Related]
13. Adenovirus regulates sumoylation of Mre11-Rad50-Nbs1 components through a paralog-specific mechanism.
Sohn SY; Hearing P
J Virol; 2012 Sep; 86(18):9656-65. PubMed ID: 22740413
[TBL] [Abstract][Full Text] [Related]
14. MRN (MRE11-RAD50-NBS1) Complex in Human Cancer and Prognostic Implications in Colorectal Cancer.
Situ Y; Chung L; Lee CS; Ho V
Int J Mol Sci; 2019 Feb; 20(4):. PubMed ID: 30769804
[TBL] [Abstract][Full Text] [Related]
15. Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy.
Chang L; Huang J; Wang K; Li J; Yan R; Zhu L; Ye J; Wu X; Zhuang S; Li D; Zhang G
BMC Cancer; 2016 Mar; 16():190. PubMed ID: 26951044
[TBL] [Abstract][Full Text] [Related]
16. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein.
Zhou H; Kawamura K; Yanagihara H; Kobayashi J; Zhang-Akiyama QM
J Radiat Res; 2017 Jul; 58(4):487-494. PubMed ID: 28369484
[TBL] [Abstract][Full Text] [Related]
17. Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity.
Kim H; Choi H; Im JS; Park SY; Shin G; Yoo JH; Kim G; Lee JK
J Biol Chem; 2021 Oct; 297(4):101148. PubMed ID: 34473993
[TBL] [Abstract][Full Text] [Related]
18. Importance of Germline and Somatic Alterations in Human
Otahalova B; Volkova Z; Soukupova J; Kleiblova P; Janatova M; Vocka M; Macurek L; Kleibl Z
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982687
[TBL] [Abstract][Full Text] [Related]
19. Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex.
Lentz TB; Samulski RJ
J Virol; 2015 Jan; 89(1):181-94. PubMed ID: 25320294
[TBL] [Abstract][Full Text] [Related]
20. Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1.
Kim H; Kim D; Choi H; Shin G; Lee JK
J Biol Chem; 2023 Jan; 299(1):102752. PubMed ID: 36436562
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]