BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 21622566)

  • 1. Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic β-cell function and vascularization.
    Soesanto Y; Luo B; Parker G; Jones D; Cooksey RC; McClain DA
    J Biol Chem; 2011 Jul; 286(29):26118-26. PubMed ID: 21622566
    [TBL] [Abstract][Full Text] [Related]  

  • 2. O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells.
    Durning SP; Flanagan-Steet H; Prasad N; Wells L
    J Biol Chem; 2016 Jan; 291(5):2107-18. PubMed ID: 26598517
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.
    Akimoto Y; Hart GW; Wells L; Vosseller K; Yamamoto K; Munetomo E; Ohara-Imaizumi M; Nishiwaki C; Nagamatsu S; Hirano H; Kawakami H
    Glycobiology; 2007 Feb; 17(2):127-40. PubMed ID: 17095531
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion.
    Liu K; Paterson AJ; Konrad RJ; Parlow AF; Jimi S; Roh M; Chin E; Kudlow JE
    Mol Cell Endocrinol; 2002 Aug; 194(1-2):135-46. PubMed ID: 12242036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells.
    de Queiroz RM; Madan R; Chien J; Dias WB; Slawson C
    J Biol Chem; 2016 Sep; 291(36):18897-914. PubMed ID: 27402830
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.
    Vosseller K; Wells L; Lane MD; Hart GW
    Proc Natl Acad Sci U S A; 2002 Apr; 99(8):5313-8. PubMed ID: 11959983
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells.
    Hanover JA; Lai Z; Lee G; Lubas WA; Sato SM
    Arch Biochem Biophys; 1999 Feb; 362(1):38-45. PubMed ID: 9917327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes.
    Park SY; Ryu J; Lee W
    Exp Mol Med; 2005 Jun; 37(3):220-9. PubMed ID: 16000877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
    Forsythe ME; Love DC; Lazarus BD; Kim EJ; Prinz WA; Ashwell G; Krause MW; Hanover JA
    Proc Natl Acad Sci U S A; 2006 Aug; 103(32):11952-7. PubMed ID: 16882729
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinal O-linked N-acetylglucosamine protein modifications: implications for postnatal retinal vascularization and the pathogenesis of diabetic retinopathy.
    Gurel Z; Sieg KM; Shallow KD; Sorenson CM; Sheibani N
    Mol Vis; 2013; 19():1047-59. PubMed ID: 23734074
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans.
    Rahman MM; Stuchlick O; El-Karim EG; Stuart R; Kipreos ET; Wells L
    Aging (Albany NY); 2010 Oct; 2(10):678-90. PubMed ID: 20952811
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pancreatic β-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasis
    Jo S; Pritchard S; Wong A; Avula N; Essawy A; Hanover J; Alejandro EU
    Front Endocrinol (Lausanne); 2022; 13():1040014. PubMed ID: 36387851
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain.
    Liu Y; Li X; Yu Y; Shi J; Liang Z; Run X; Li Y; Dai CL; Grundke-Iqbal I; Iqbal K; Liu F; Gong CX
    PLoS One; 2012; 7(8):e43724. PubMed ID: 22928023
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic analysis of O-GlcNAc modifications derived from streptozotocin and glucosamine induced beta-cell apoptosis.
    Park J; Kwon H; Kang Y; Kim Y
    J Biochem Mol Biol; 2007 Nov; 40(6):1058-68. PubMed ID: 18047804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.
    Ball LE; Berkaw MN; Buse MG
    Mol Cell Proteomics; 2006 Feb; 5(2):313-23. PubMed ID: 16244361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The hexosamine signaling pathway: deciphering the "O-GlcNAc code".
    Love DC; Hanover JA
    Sci STKE; 2005 Nov; 2005(312):re13. PubMed ID: 16317114
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology.
    Vaidyanathan K; Durning S; Wells L
    Crit Rev Biochem Mol Biol; 2014; 49(2):140-163. PubMed ID: 24524620
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure.
    Alejandro EU; Bozadjieva N; Kumusoglu D; Abdulhamid S; Levine H; Haataja L; Vadrevu S; Satin LS; Arvan P; Bernal-Mizrachi E
    Cell Rep; 2015 Dec; 13(11):2527-2538. PubMed ID: 26673325
    [TBL] [Abstract][Full Text] [Related]  

  • 19. O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice.
    Makino A; Dai A; Han Y; Youssef KD; Wang W; Donthamsetty R; Scott BT; Wang H; Dillmann WH
    Am J Physiol Cell Physiol; 2015 Nov; 309(9):C593-9. PubMed ID: 26269457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucose mediates the translocation of NeuroD1 by O-linked glycosylation.
    Andrali SS; Qian Q; Ozcan S
    J Biol Chem; 2007 May; 282(21):15589-96. PubMed ID: 17403669
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.