BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 21622941)

  • 1. Site-specific in vivo mutagenicity in the kidney of gpt delta rats given a carcinogenic dose of ochratoxin A.
    Hibi D; Suzuki Y; Ishii Y; Jin M; Watanabe M; Sugita-Konishi Y; Yanai T; Nohmi T; Nishikawa A; Umemura T
    Toxicol Sci; 2011 Aug; 122(2):406-14. PubMed ID: 21622941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of p53 knockout on ochratoxin A-induced genotoxicity in p53-deficient gpt delta mice.
    Hibi D; Kijima A; Suzuki Y; Ishii Y; Jin M; Sugita-Konishi Y; Yanai T; Nishikawa A; Umemura T
    Toxicology; 2013 Feb; 304():92-9. PubMed ID: 23261758
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats.
    Kuroda K; Hibi D; Ishii Y; Takasu S; Kijima A; Matsushita K; Masumura K; Watanabe M; Sugita-Konishi Y; Sakai H; Yanai T; Nohmi T; Ogawa K; Umemura T
    Mutagenesis; 2014 Jan; 29(1):27-36. PubMed ID: 24243707
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ochratoxin a causes DNA damage and cytogenetic effects but no DNA adducts in rats.
    Mally A; Pepe G; Ravoori S; Fiore M; Gupta RC; Dekant W; Mosesso P
    Chem Res Toxicol; 2005 Aug; 18(8):1253-61. PubMed ID: 16097798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduction in antioxidant defenses may contribute to ochratoxin A toxicity and carcinogenicity.
    Cavin C; Delatour T; Marin-Kuan M; Holzhäuser D; Higgins L; Bezençon C; Guignard G; Junod S; Richoz-Payot J; Gremaud E; Hayes JD; Nestler S; Mantle P; Schilter B
    Toxicol Sci; 2007 Mar; 96(1):30-9. PubMed ID: 17110534
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional, biochemical, and pathological effects of repeated oral administration of ochratoxin A to rats.
    Mally A; Völkel W; Amberg A; Kurz M; Wanek P; Eder E; Hard G; Dekant W
    Chem Res Toxicol; 2005 Aug; 18(8):1242-52. PubMed ID: 16097797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ochratoxin A: 13-week oral toxicity and cell proliferation in male F344/n rats.
    Rached E; Hard GC; Blumbach K; Weber K; Draheim R; Lutz WK; Ozden S; Steger U; Dekant W; Mally A
    Toxicol Sci; 2007 Jun; 97(2):288-98. PubMed ID: 17344223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new approach to studying ochratoxin A (OTA)-induced nephrotoxicity: expression profiling in vivo and in vitro employing cDNA microarrays.
    Luhe A; Hildebrand H; Bach U; Dingermann T; Ahr HJ
    Toxicol Sci; 2003 Jun; 73(2):315-28. PubMed ID: 12700408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats.
    Taniai E; Yafune A; Nakajima M; Hayashi SM; Nakane F; Itahashi M; Shibutani M
    Toxicol Lett; 2014 Jan; 224(1):64-72. PubMed ID: 24120684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mechanisms underlying ochratoxin A-induced genotoxicity: global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression.
    Hibi D; Kijima A; Kuroda K; Suzuki Y; Ishii Y; Jin M; Nakajima M; Sugita-Konishi Y; Yanai T; Nohmi T; Nishikawa A; Umemura T
    J Toxicol Sci; 2013 Feb; 38(1):57-69. PubMed ID: 23358140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats.
    Kamp HG; Eisenbrand G; Janzowski C; Kiossev J; Latendresse JR; Schlatter J; Turesky RJ
    Mol Nutr Food Res; 2005 Dec; 49(12):1160-7. PubMed ID: 16302199
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice.
    Umemura T; Kuroiwa Y; Tasaki M; Okamura T; Ishii Y; Kodama Y; Nohmi T; Mitsumori K; Nishikawa A; Hirose M
    Mutat Res; 2007 Sep; 633(1):46-54. PubMed ID: 17581771
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Possible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromate.
    Umemura T; Tasaki M; Kijima A; Okamura T; Inoue T; Ishii Y; Suzuki Y; Masui N; Nohmi T; Nishikawa A
    Toxicology; 2009 Mar; 257(1-2):46-52. PubMed ID: 19133310
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE; Walker DM; Meng Q; McDonald JD; Scott BR; Seilkop SK; Claffey DJ; Upton PB; Powley MW; Swenberg JA; Henderson RF;
    Res Rep Health Eff Inst; 2009 Aug; (144):3-79. PubMed ID: 20017413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative DNA damage induced by Ochratoxin A in the HK-2 human kidney cell line: evidence of the relationship with cytotoxicity.
    Arbillaga L; Azqueta A; Ezpeleta O; López de Cerain A
    Mutagenesis; 2007 Jan; 22(1):35-42. PubMed ID: 17130176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biotransformation and nephrotoxicity of ochratoxin B in rats.
    Mally A; Keim-Heusler H; Amberg A; Kurz M; Zepnik H; Mantle P; Völkel W; Hard GC; Dekant W
    Toxicol Appl Pharmacol; 2005 Aug; 206(1):43-53. PubMed ID: 15963343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ochratoxin A: induction of (oxidative) DNA damage, cytotoxicity and apoptosis in mammalian cell lines and primary cells.
    Kamp HG; Eisenbrand G; Schlatter J; Würth K; Janzowski C
    Toxicology; 2005 Jan; 206(3):413-25. PubMed ID: 15588931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies.
    Kawamura Y; Hayashi H; Kurata Y; Hiratsuka K; Masumura K; Nohmi T
    Toxicology; 2013 Oct; 312():56-62. PubMed ID: 23907062
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA damage and micronuclei induced in rat and human kidney cells by six chemicals carcinogenic to the rat kidney.
    Robbiano L; Baroni D; Carrozzino R; Mereto E; Brambilla G
    Toxicology; 2004 Nov; 204(2-3):187-95. PubMed ID: 15388244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cellular distribution of cell cycle-related molecules in the renal tubules of rats treated with renal carcinogens for 28 days: relationship between cell cycle aberration and carcinogenesis.
    Taniai E; Hayashi H; Yafune A; Watanabe M; Akane H; Suzuki K; Mitsumori K; Shibutani M
    Arch Toxicol; 2012 Sep; 86(9):1453-64. PubMed ID: 22411272
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.