BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

396 related articles for article (PubMed ID: 21625534)

  • 1. AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.
    Johnson JS; Gentzsch M; Zhang L; Ribeiro CM; Kantor B; Kafri T; Pickles RJ; Samulski RJ
    PLoS Pathog; 2011 May; 7(5):e1002053. PubMed ID: 21625534
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels.
    Saxena A; Banasavadi-Siddegowda YK; Fan Y; Bhattacharya S; Roy G; Giovannucci DR; Frizzell RA; Wang X
    J Biol Chem; 2012 Jun; 287(23):19158-70. PubMed ID: 22505710
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia.
    Ribeiro CM; Paradiso AM; Carew MA; Shears SB; Boucher RC
    J Biol Chem; 2005 Mar; 280(11):10202-9. PubMed ID: 15647273
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Base treatment corrects defects due to misfolding of mutant cystic fibrosis transmembrane conductance regulator.
    Namkung W; Kim KH; Lee MG
    Gastroenterology; 2005 Dec; 129(6):1979-90. PubMed ID: 16344066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.
    Wang X; Venable J; LaPointe P; Hutt DM; Koulov AV; Coppinger J; Gurkan C; Kellner W; Matteson J; Plutner H; Riordan JR; Kelly JW; Yates JR; Balch WE
    Cell; 2006 Nov; 127(4):803-15. PubMed ID: 17110338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A posttranslational modification code for CFTR maturation is altered in cystic fibrosis.
    Pankow S; Bamberger C; Yates JR
    Sci Signal; 2019 Jan; 12(562):. PubMed ID: 30600261
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DeltaF508 CFTR.
    Okiyoneda T; Niibori A; Harada K; Kohno T; Michalak M; Duszyk M; Wada I; Ikawa M; Shuto T; Suico MA; Kai H
    Biochim Biophys Acta; 2008 Sep; 1783(9):1585-94. PubMed ID: 18457676
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi.
    Farinha CM; Matos P; Amaral MD
    FEBS J; 2013 Sep; 280(18):4396-406. PubMed ID: 23773658
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect.
    Veit G; Oliver K; Apaja PM; Perdomo D; Bidaud-Meynard A; Lin ST; Guo J; Icyuz M; Sorscher EJ; Hartman JL; Lukacs GL
    PLoS Biol; 2016 May; 14(5):e1002462. PubMed ID: 27168400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coupling cystic fibrosis to endoplasmic reticulum stress: Differential role of Grp78 and ATF6.
    Kerbiriou M; Le Drévo MA; Férec C; Trouvé P
    Biochim Biophys Acta; 2007 Dec; 1772(11-12):1236-49. PubMed ID: 18022401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR.
    Sabirzhanova I; Boinot C; Guggino WB; Cebotaru L
    Cell Physiol Biochem; 2018; 51(3):1489-1499. PubMed ID: 30485852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications.
    Vij N; Fang S; Zeitlin PL
    J Biol Chem; 2006 Jun; 281(25):17369-17378. PubMed ID: 16621797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.
    Suaud L; Miller K; Alvey L; Yan W; Robay A; Kebler C; Kreindler JL; Guttentag S; Hubbard MJ; Rubenstein RC
    J Biol Chem; 2011 Jun; 286(24):21239-53. PubMed ID: 21525008
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The CFTR-Associated Ligand Arrests the Trafficking of the Mutant ΔF508 CFTR Channel in the ER Contributing to Cystic Fibrosis.
    Bergbower E; Boinot C; Sabirzhanova I; Guggino W; Cebotaru L
    Cell Physiol Biochem; 2018; 45(2):639-655. PubMed ID: 29402832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras.
    Haggie PM; Stanton BA; Verkman AS
    J Biol Chem; 2002 May; 277(19):16419-25. PubMed ID: 11877404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells.
    Singh OV; Pollard HB; Zeitlin PL
    Mol Cell Proteomics; 2008 Jun; 7(6):1099-110. PubMed ID: 18285607
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs.
    Knorre A; Wagner M; Schaefer HE; Colledge WH; Pahl HL
    Biol Chem; 2002 Feb; 383(2):271-82. PubMed ID: 11934265
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Use of kinase inhibitors to correct ΔF508-CFTR function.
    Trzcinska-Daneluti AM; Nguyen L; Jiang C; Fladd C; Uehling D; Prakesch M; Al-awar R; Rotin D
    Mol Cell Proteomics; 2012 Sep; 11(9):745-57. PubMed ID: 22700489
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Correctors promote folding of the CFTR in the endoplasmic reticulum.
    Loo TW; Bartlett MC; Clarke DM
    Biochem J; 2008 Jul; 413(1):29-36. PubMed ID: 18361776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of molecular determinants that modulate trafficking of DeltaF508 CFTR, the mutant ABC transporter associated with cystic fibrosis.
    Tsigelny I; Hotchko M; Yuan JX; Keller SH
    Cell Biochem Biophys; 2005; 42(1):41-53. PubMed ID: 15673927
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.