BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 21625597)

  • 1. Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation.
    Butturini E; Cavalieri E; de Prati AC; Darra E; Rigo A; Shoji K; Murayama N; Yamazaki H; Watanabe Y; Suzuki H; Mariotto S
    PLoS One; 2011; 6(5):e20174. PubMed ID: 21625597
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs.
    Butturini E; Carcereri de Prati A; Chiavegato G; Rigo A; Cavalieri E; Darra E; Mariotto S
    Free Radic Biol Med; 2013 Dec; 65():1322-1330. PubMed ID: 24095958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide.
    Scarponi C; Butturini E; Sestito R; Madonna S; Cavani A; Mariotto S; Albanesi C
    PLoS One; 2014; 9(9):e107904. PubMed ID: 25226283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice.
    Butturini E; Di Paola R; Suzuki H; Paterniti I; Ahmad A; Mariotto S; Cuzzocrea S
    Eur J Pharmacol; 2014 May; 730():107-15. PubMed ID: 24625594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells.
    Zhang HH; Kuang S; Wang Y; Sun XX; Gu Y; Hu LH; Yu Q
    Acta Pharmacol Sin; 2015 Apr; 36(4):507-16. PubMed ID: 25619393
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes.
    Kurdi M; Sivakumaran V; Duhé RJ; Aon MA; Paolocci N; Booz GW
    Int J Biochem Cell Biol; 2012 Dec; 44(12):2106-15. PubMed ID: 22939972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Costunolide, a Sesquiterpene Lactone, Suppresses Skin Cancer via Induction of Apoptosis and Blockage of Cell Proliferation.
    Lee SH; Cho YC; Lim JS
    Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33669832
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling.
    Xie Y; Kole S; Precht P; Pazin MJ; Bernier M
    Endocrinology; 2009 Mar; 150(3):1122-31. PubMed ID: 18988672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence that IL-6-type cytokine signaling in cardiomyocytes is inhibited by oxidative stress: parthenolide targets JAK1 activation by generating ROS.
    Kurdi M; Booz GW
    J Cell Physiol; 2007 Aug; 212(2):424-31. PubMed ID: 17385713
    [TBL] [Abstract][Full Text] [Related]  

  • 10. S-Glutathionylation at Cys328 and Cys542 impairs STAT3 phosphorylation.
    Butturini E; Darra E; Chiavegato G; Cellini B; Cozzolino F; Monti M; Pucci P; Dell'Orco D; Mariotto S
    ACS Chem Biol; 2014 Aug; 9(8):1885-93. PubMed ID: 24941337
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile.
    Liu YC; Hsieh CW; Wu CC; Wung BS
    Life Sci; 2007 Mar; 80(15):1420-30. PubMed ID: 17320913
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.
    Yeh CT; Huang WC; Rao YK; Ye M; Lee WH; Wang LS; Tzeng DT; Wu CH; Shieh YS; Huang CY; Chen YJ; Hsiao M; Wu AT; Yang Z; Tzeng YM
    Carcinogenesis; 2013 Dec; 34(12):2918-28. PubMed ID: 23880305
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Natural Sesquiterpene Lactones Enhance Chemosensitivity of Tumor Cells through Redox Regulation of STAT3 Signaling.
    Butturini E; Carcereri de Prati A; Boriero D; Mariotto S
    Oxid Med Cell Longev; 2019; 2019():4568964. PubMed ID: 31781335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dehydrocostuslactone disrupts signal transducers and activators of transcription 3 through up-regulation of suppressor of cytokine signaling in breast cancer cells.
    Kuo PL; Ni WC; Tsai EM; Hsu YL
    Mol Cancer Ther; 2009 May; 8(5):1328-39. PubMed ID: 19383849
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Helicobacter pylori Activates IL-6-STAT3 Signaling in Human Gastric Cancer Cells: Potential Roles for Reactive Oxygen Species.
    Piao JY; Lee HG; Kim SJ; Kim DH; Han HJ; Ngo HK; Park SA; Woo JH; Lee JS; Na HK; Cha YN; Surh YJ
    Helicobacter; 2016 Oct; 21(5):405-16. PubMed ID: 26910614
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sesquiterpene lactones-enriched fraction of Inula helenium L. induces apoptosis through inhibition of signal transducers and activators of transcription 3 signaling pathway in MDA-MB-231 breast cancer cells.
    Chun J; Song K; Kim YS
    Phytother Res; 2018 Dec; 32(12):2501-2509. PubMed ID: 30251272
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
    Maryam A; Mehmood T; Zhang H; Li Y; Khan M; Ma T
    Sci Rep; 2017 Jul; 7(1):6242. PubMed ID: 28740138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I.
    Fu XQ; Chou JY; Li T; Zhu PL; Li JK; Yin CL; Su T; Guo H; Lee KW; Hossen MJ; Chou GX; Yu ZL
    Exp Dermatol; 2018 Feb; 27(2):201-204. PubMed ID: 29078004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer.
    Yang B; Shen JW; Zhou DH; Zhao YP; Wang WQ; Zhu Y; Zhao HJ
    Nat Prod Res; 2019 Feb; 33(4):477-485. PubMed ID: 29086600
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 15-Lipoxygenase-1-enhanced Src-Janus kinase 2-signal transducer and activator of transcription 3 stimulation and monocyte chemoattractant protein-1 expression require redox-sensitive activation of epidermal growth factor receptor in vascular wall remodeling.
    Singh NK; Wang D; Kundumani-Sridharan V; Van Quyen D; Niu J; Rao GN
    J Biol Chem; 2011 Jun; 286(25):22478-88. PubMed ID: 21536676
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.