156 related articles for article (PubMed ID: 21633987)
21. Ultrafast real-time visualization of active site flexibility of flavoenzyme thymidylate synthase ThyX.
Laptenok SP; Bouzhir-Sima L; Lambry JC; Myllykallio H; Liebl U; Vos MH
Proc Natl Acad Sci U S A; 2013 May; 110(22):8924-9. PubMed ID: 23671075
[TBL] [Abstract][Full Text] [Related]
22. Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei.
Finer-Moore J; Fauman EB; Foster PG; Perry KM; Santi DV; Stroud RM
J Mol Biol; 1993 Aug; 232(4):1101-16. PubMed ID: 8371269
[TBL] [Abstract][Full Text] [Related]
23. Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Finer-Moore JS; Liu L; Schafmeister CE; Birdsall DL; Mau T; Santi DV; Stroud RM
Biochemistry; 1996 Apr; 35(16):5125-36. PubMed ID: 8611496
[TBL] [Abstract][Full Text] [Related]
24. Effects of subunit occupancy on partitioning of an intermediate in thymidylate synthase mutants.
Variath P; Liu Y; Lee TT; Stroud RM; Santi DV
Biochemistry; 2000 Mar; 39(10):2429-35. PubMed ID: 10704192
[TBL] [Abstract][Full Text] [Related]
25. Isolation of a covalent steady-state intermediate in glutamate 60 mutants of thymidylate synthase.
Huang W; Santi DV
J Biol Chem; 1994 Dec; 269(50):31327-9. PubMed ID: 7989294
[TBL] [Abstract][Full Text] [Related]
26. Thermal stability and binding energetics of thymidylate synthase ThyX.
Krumova S; Todinova S; Tileva M; Bouzhir-Sima L; Vos MH; Liebl U; Taneva SG
Int J Biol Macromol; 2016 Oct; 91():560-7. PubMed ID: 27268384
[TBL] [Abstract][Full Text] [Related]
27. The catalytic mechanism and structure of thymidylate synthase.
Carreras CW; Santi DV
Annu Rev Biochem; 1995; 64():721-62. PubMed ID: 7574499
[TBL] [Abstract][Full Text] [Related]
28. Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein.
Mathews II; Deacon AM; Canaves JM; McMullan D; Lesley SA; Agarwalla S; Kuhn P
Structure; 2003 Jun; 11(6):677-90. PubMed ID: 12791256
[TBL] [Abstract][Full Text] [Related]
29. Aspartate 221 of thymidylate synthase is involved in folate cofactor binding and in catalysis.
Chiericatti G; Santi DV
Biochemistry; 1998 Jun; 37(25):9038-42. PubMed ID: 9636048
[TBL] [Abstract][Full Text] [Related]
30. The effect of 5-substitution in the pyrimidine ring of dUMP on the interaction with thymidylate synthase: molecular modeling and QSAR.
Jarmuła A; Cieplak P; Krygowski TM; Rode W
Bioorg Med Chem; 2007 Mar; 15(6):2346-58. PubMed ID: 17275316
[TBL] [Abstract][Full Text] [Related]
31. Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Phan J; Mahdavian E; Nivens MC; Minor W; Berger S; Spencer HT; Dunlap RB; Lebioda L
Biochemistry; 2000 Jun; 39(23):6969-78. PubMed ID: 10841779
[TBL] [Abstract][Full Text] [Related]
32. Asparagine 229 mutants of thymidylate synthase catalyze the methylation of 3-methyl-2'-deoxyuridine 5'-monophosphate.
Costi PM; Liu L; Finer-Moore JS; Stroud RM; Santi DV
Biochemistry; 1996 Apr; 35(13):3944-9. PubMed ID: 8672425
[TBL] [Abstract][Full Text] [Related]
33. Crystal structure of the active form of native human thymidylate synthase in the absence of bound substrates.
Deschamps P; Réty S; Bareille J; Leulliot N
Acta Crystallogr F Struct Biol Commun; 2017 Jun; 73(Pt 6):336-341. PubMed ID: 28580921
[TBL] [Abstract][Full Text] [Related]
34. Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase.
Finer-Moore JS; Fauman EB; Morse RJ; Santi DV; Stroud RM
Protein Eng; 1996 Jan; 9(1):69-75. PubMed ID: 9053905
[TBL] [Abstract][Full Text] [Related]
35. Effect of halogen substitutions on dUMP to stability of thymidylate synthase/dUMP/mTHF ternary complex using molecular dynamics simulation.
Kaiyawet N; Rungrotmongkol T; Hannongbua S
J Chem Inf Model; 2013 Jun; 53(6):1315-23. PubMed ID: 23705822
[TBL] [Abstract][Full Text] [Related]
36. Cloning, expression, and enzymatic characterization of isocitrate dehydrogenase from Helicobacter pylori.
Huang D; Liu J; Shen G
Protein J; 2009 Dec; 28(9-10):443-7. PubMed ID: 19921412
[TBL] [Abstract][Full Text] [Related]
37. Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Almog R; Waddling CA; Maley F; Maley GF; Van Roey P
Protein Sci; 2001 May; 10(5):988-96. PubMed ID: 11316879
[TBL] [Abstract][Full Text] [Related]
38. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261.
Newby Z; Lee TT; Morse RJ; Liu Y; Liu L; Venkatraman P; Santi DV; Finer-Moore JS; Stroud RM
Biochemistry; 2006 Jun; 45(24):7415-28. PubMed ID: 16768437
[TBL] [Abstract][Full Text] [Related]
39. Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.
Graziani S; Bernauer J; Skouloubris S; Graille M; Zhou CZ; Marchand C; Decottignies P; van Tilbeurgh H; Myllykallio H; Liebl U
J Biol Chem; 2006 Aug; 281(33):24048-57. PubMed ID: 16707489
[TBL] [Abstract][Full Text] [Related]
40. A novel dCMP methylase by engineering thymidylate synthase.
Agarwalla S; LaPorte S; Liu L; Finer-Moore J; Stroud RM; Santi DV
Biochemistry; 1997 Dec; 36(50):15909-17. PubMed ID: 9398324
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
