131 related articles for article (PubMed ID: 21637660)
1. Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide.
Brassesco MS; Montaldi AP; Sakamoto-Hojo ET
Genet Mol Biol; 2009 Jan; 32(1):144-50. PubMed ID: 21637660
[TBL] [Abstract][Full Text] [Related]
2. MLL rearrangements are induced by low doses of etoposide in human fetal hematopoietic stem cells.
Moneypenny CG; Shao J; Song Y; Gallagher EP
Carcinogenesis; 2006 Apr; 27(4):874-81. PubMed ID: 16377807
[TBL] [Abstract][Full Text] [Related]
3. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
Domer PH; Head DR; Renganathan N; Raimondi SC; Yang E; Atlas M
Leukemia; 1995 Aug; 9(8):1305-12. PubMed ID: 7643617
[TBL] [Abstract][Full Text] [Related]
4. Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.
Libura J; Slater DJ; Felix CA; Richardson C
Blood; 2005 Mar; 105(5):2124-31. PubMed ID: 15528316
[TBL] [Abstract][Full Text] [Related]
5. Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.
Nakada S; Katsuki Y; Imoto I; Yokoyama T; Nagasawa M; Inazawa J; Mizutani S
J Clin Invest; 2006 Jan; 116(1):80-9. PubMed ID: 16357944
[TBL] [Abstract][Full Text] [Related]
6. Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential.
Libura J; Ward M; Solecka J; Richardson C
Eur J Haematol; 2008 Sep; 81(3):185-95. PubMed ID: 18510699
[TBL] [Abstract][Full Text] [Related]
7. Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
Sung PA; Libura J; Richardson C
DNA Repair (Amst); 2006 Sep; 5(9-10):1109-18. PubMed ID: 16809075
[TBL] [Abstract][Full Text] [Related]
8. Cytogenetic and molecular analysis of MLL rearrangements in acute lymphoblastic leukaemia survivors.
Brassesco MS; Montaldi AP; Gras DE; Camparoto ML; Martinez-Rossi NM; Scrideli CA; Tone LG; Sakamoto-Hojo ET
Mutagenesis; 2009 Mar; 24(2):153-60. PubMed ID: 19028982
[TBL] [Abstract][Full Text] [Related]
9. Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II.
Super HJ; McCabe NR; Thirman MJ; Larson RA; Le Beau MM; Pedersen-Bjergaard J; Philip P; Diaz MO; Rowley JD
Blood; 1993 Dec; 82(12):3705-11. PubMed ID: 8260707
[TBL] [Abstract][Full Text] [Related]
10. Secondary leukemia associated with the anti-cancer agent, etoposide, a topoisomerase II inhibitor.
Ezoe S
Int J Environ Res Public Health; 2012 Jul; 9(7):2444-53. PubMed ID: 22851953
[TBL] [Abstract][Full Text] [Related]
11. MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals.
Brassesco MS; Montaldi AP; Gras DE; de Paula Queiroz RG; Martinez-Rossi NM; Tone LG; Sakamoto-Hojo ET
Genet Mol Biol; 2009 Apr; 32(2):234-41. PubMed ID: 21637673
[TBL] [Abstract][Full Text] [Related]
12. Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells.
Bueno C; Catalina P; Melen GJ; Montes R; Sánchez L; Ligero G; García-Pérez JL; Menendez P
Carcinogenesis; 2009 Sep; 30(9):1628-37. PubMed ID: 19587093
[TBL] [Abstract][Full Text] [Related]
13. Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
Cowell IG; Sondka Z; Smith K; Lee KC; Manville CM; Sidorczuk-Lesthuruge M; Rance HA; Padget K; Jackson GH; Adachi N; Austin CA
Proc Natl Acad Sci U S A; 2012 Jun; 109(23):8989-94. PubMed ID: 22615413
[TBL] [Abstract][Full Text] [Related]
14. Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
Lovett BD; Strumberg D; Blair IA; Pang S; Burden DA; Megonigal MD; Rappaport EF; Rebbeck TR; Osheroff N; Pommier YG; Felix CA
Biochemistry; 2001 Feb; 40(5):1159-70. PubMed ID: 11170441
[TBL] [Abstract][Full Text] [Related]
15. Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors.
Aplan PD; Chervinsky DS; Stanulla M; Burhans WC
Blood; 1996 Apr; 87(7):2649-58. PubMed ID: 8639880
[TBL] [Abstract][Full Text] [Related]
16. Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations.
Thirman MJ; Gill HJ; Burnett RC; Mbangkollo D; McCabe NR; Kobayashi H; Ziemin-van der Poel S; Kaneko Y; Morgan R; Sandberg AA
N Engl J Med; 1993 Sep; 329(13):909-14. PubMed ID: 8361504
[TBL] [Abstract][Full Text] [Related]
17. Leukaemia-specific chromosome damage detected by comet with fluorescence in situ hybridization (comet-FISH).
Escobar PA; Smith MT; Vasishta A; Hubbard AE; Zhang L
Mutagenesis; 2007 Sep; 22(5):321-7. PubMed ID: 17575318
[TBL] [Abstract][Full Text] [Related]
18. Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.
McCabe NR; Burnett RC; Gill HJ; Thirman MJ; Mbangkollo D; Kipiniak M; van Melle E; Ziemin-van der Poel S; Rowley JD; Diaz MO
Proc Natl Acad Sci U S A; 1992 Dec; 89(24):11794-8. PubMed ID: 1465401
[TBL] [Abstract][Full Text] [Related]
19. ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
Felix CA; Hosler MR; Winick NJ; Masterson M; Wilson AE; Lange BJ
Blood; 1995 Jun; 85(11):3250-6. PubMed ID: 7756657
[TBL] [Abstract][Full Text] [Related]
20. DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis.
Stanulla M; Wang J; Chervinsky DS; Thandla S; Aplan PD
Mol Cell Biol; 1997 Jul; 17(7):4070-9. PubMed ID: 9199342
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]