These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 21639679)

  • 21. ESNATS conference - the use of human embryonic stem cells for novel toxicity testing approaches.
    Rovida C; Vivier M; Garthoff B; Hescheler J
    Altern Lab Anim; 2014 May; 42(2):97-113. PubMed ID: 24901904
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 3D engineered In vitro hepatospheroids for studying drug toxicity and metabolism.
    Chitrangi S; Nair P; Khanna A
    Toxicol In Vitro; 2017 Feb; 38():8-18. PubMed ID: 27794450
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
    Godoy P; Hewitt NJ; Albrecht U; Andersen ME; Ansari N; Bhattacharya S; Bode JG; Bolleyn J; Borner C; Böttger J; Braeuning A; Budinsky RA; Burkhardt B; Cameron NR; Camussi G; Cho CS; Choi YJ; Craig Rowlands J; Dahmen U; Damm G; Dirsch O; Donato MT; Dong J; Dooley S; Drasdo D; Eakins R; Ferreira KS; Fonsato V; Fraczek J; Gebhardt R; Gibson A; Glanemann M; Goldring CE; Gómez-Lechón MJ; Groothuis GM; Gustavsson L; Guyot C; Hallifax D; Hammad S; Hayward A; Häussinger D; Hellerbrand C; Hewitt P; Hoehme S; Holzhütter HG; Houston JB; Hrach J; Ito K; Jaeschke H; Keitel V; Kelm JM; Kevin Park B; Kordes C; Kullak-Ublick GA; LeCluyse EL; Lu P; Luebke-Wheeler J; Lutz A; Maltman DJ; Matz-Soja M; McMullen P; Merfort I; Messner S; Meyer C; Mwinyi J; Naisbitt DJ; Nussler AK; Olinga P; Pampaloni F; Pi J; Pluta L; Przyborski SA; Ramachandran A; Rogiers V; Rowe C; Schelcher C; Schmich K; Schwarz M; Singh B; Stelzer EH; Stieger B; Stöber R; Sugiyama Y; Tetta C; Thasler WE; Vanhaecke T; Vinken M; Weiss TS; Widera A; Woods CG; Xu JJ; Yarborough KM; Hengstler JG
    Arch Toxicol; 2013 Aug; 87(8):1315-530. PubMed ID: 23974980
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Toxicity testing and drug screening using iPSC-derived hepatocytes, cardiomyocytes, and neural cells.
    Csöbönyeiová M; Polák Š; Danišovič L
    Can J Physiol Pharmacol; 2016 Jul; 94(7):687-94. PubMed ID: 27128322
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Chemically induced hepatotoxicity in human stem cell-induced hepatocytes compared with primary hepatocytes and HepG2.
    Kang SJ; Lee HM; Park YI; Yi H; Lee H; So B; Song JY; Kang HG
    Cell Biol Toxicol; 2016 Oct; 32(5):403-17. PubMed ID: 27287938
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective.
    Calitz C; Hamman JH; Fey SJ; Wrzesinski K; Gouws C
    Toxicol Mech Methods; 2018 Jun; 28(5):369-385. PubMed ID: 29297242
    [TBL] [Abstract][Full Text] [Related]  

  • 27. In vitro transcriptomic prediction of hepatotoxicity for early drug discovery.
    Cheng F; Theodorescu D; Schulman IG; Lee JK
    J Theor Biol; 2011 Dec; 290():27-36. PubMed ID: 21884709
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals.
    Rodrigues RM; De Kock J; Branson S; Vinken M; Meganathan K; Chaudhari U; Sachinidis A; Govaere O; Roskams T; De Boe V; Vanhaecke T; Rogiers V
    Stem Cells Dev; 2014 Jan; 23(1):44-55. PubMed ID: 23952781
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.
    Rodrigues RM; Heymans A; De Boe V; Sachinidis A; Chaudhari U; Govaere O; Roskams T; Vanhaecke T; Rogiers V; De Kock J
    Toxicol Lett; 2016 Jan; 240(1):50-9. PubMed ID: 26497421
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Three-dimensional co-culture of primary human liver cells in bioreactors for in vitro drug studies: effects of the initial cell quality on the long-term maintenance of hepatocyte-specific functions.
    Zeilinger K; Sauer IM; Pless G; Strobel C; Rudzitis J; Wang A; Nüssler AK; Grebe A; Mao L; Auth SH; Unger J; Neuhaus P; Gerlach JC
    Altern Lab Anim; 2002; 30(5):525-38. PubMed ID: 12405881
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity.
    Amacher DE
    Toxicol Appl Pharmacol; 2010 May; 245(1):134-42. PubMed ID: 20219512
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Drug biokinetic and toxicity assessments in rat and human primary hepatocytes and HepaRG cells within the EU-funded Predict-IV project.
    Mueller SO; Guillouzo A; Hewitt PG; Richert L
    Toxicol In Vitro; 2015 Dec; 30(1 Pt A):19-26. PubMed ID: 25952325
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hepatic cell lines for drug hepatotoxicity testing: limitations and strategies to upgrade their metabolic competence by gene engineering.
    Donato MT; Jover R; Gómez-Lechón MJ
    Curr Drug Metab; 2013 Nov; 14(9):946-68. PubMed ID: 24160292
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes.
    Nadanaciva S; Aleo MD; Strock CJ; Stedman DB; Wang H; Will Y
    Toxicol Appl Pharmacol; 2013 Oct; 272(2):272-80. PubMed ID: 23811329
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pluripotent human stem cells: A novel tool in drug discovery.
    Phillips BW; Crook JM
    BioDrugs; 2010 Apr; 24(2):99-108. PubMed ID: 20199125
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity.
    De Bruyn T; Chatterjee S; Fattah S; Keemink J; Nicolaï J; Augustijns P; Annaert P
    Expert Opin Drug Metab Toxicol; 2013 May; 9(5):589-616. PubMed ID: 23452081
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro.
    Jiang J; Pieterman CD; Ertaylan G; Peeters RLM; de Kok TMCM
    Arch Toxicol; 2019 Nov; 93(11):3067-3098. PubMed ID: 31586243
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes for In Vitro Toxicity Testing.
    Lu J; Einhorn S; Venkatarangan L; Miller M; Mann DA; Watkins PB; LeCluyse E
    Toxicol Sci; 2015 Sep; 147(1):39-54. PubMed ID: 26092927
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Concise review: Human pluripotent stem cell-based models for cardiac and hepatic toxicity assessment.
    Sartipy P; Björquist P
    Stem Cells; 2011 May; 29(5):744-8. PubMed ID: 21433222
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
    Ulvestad M; Nordell P; Asplund A; Rehnström M; Jacobsson S; Holmgren G; Davidson L; Brolén G; Edsbagge J; Björquist P; Küppers-Munther B; Andersson TB
    Biochem Pharmacol; 2013 Sep; 86(5):691-702. PubMed ID: 23856292
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.