234 related articles for article (PubMed ID: 21641936)
1. Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo.
Pinto R; Herold S; Cakarova L; Hoegner K; Lohmeyer J; Planz O; Pleschka S
Antiviral Res; 2011 Oct; 92(1):45-56. PubMed ID: 21641936
[TBL] [Abstract][Full Text] [Related]
2. Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade.
Pleschka S; Wolff T; Ehrhardt C; Hobom G; Planz O; Rapp UR; Ludwig S
Nat Cell Biol; 2001 Mar; 3(3):301-5. PubMed ID: 11231581
[TBL] [Abstract][Full Text] [Related]
3. Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy.
Ludwig S
J Antimicrob Chemother; 2009 Jul; 64(1):1-4. PubMed ID: 19420020
[TBL] [Abstract][Full Text] [Related]
4. MEK inhibition impairs influenza B virus propagation without emergence of resistant variants.
Ludwig S; Wolff T; Ehrhardt C; Wurzer WJ; Reinhardt J; Planz O; Pleschka S
FEBS Lett; 2004 Mar; 561(1-3):37-43. PubMed ID: 15013748
[TBL] [Abstract][Full Text] [Related]
5. Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo.
Droebner K; Pleschka S; Ludwig S; Planz O
Antiviral Res; 2011 Nov; 92(2):195-203. PubMed ID: 21854809
[TBL] [Abstract][Full Text] [Related]
6. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
Yang R; Piperdi S; Gorlick R
Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
[TBL] [Abstract][Full Text] [Related]
7. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM
J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
[TBL] [Abstract][Full Text] [Related]
8. BH(4) (tetrahydrobiopterin)-dependent activation, but not the expression, of inducible NOS (nitric oxide synthase)-2 in proinflammatory cytokine-stimulated, cultured normal human astrocytes is mediated by MEK-ERK kinases.
Chiarini A; Dal Pra I; Gottardo R; Bortolotti F; Whitfield JF; Armato U
J Cell Biochem; 2005 Mar; 94(4):731-43. PubMed ID: 15565652
[TBL] [Abstract][Full Text] [Related]
9. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
[TBL] [Abstract][Full Text] [Related]
10. Coordinating ERK/MAPK signalling through scaffolds and inhibitors.
Kolch W
Nat Rev Mol Cell Biol; 2005 Nov; 6(11):827-37. PubMed ID: 16227978
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Anders M; Christian C; McMahon M; McCormick F; Korn WM
Cancer Res; 2003 May; 63(9):2088-95. PubMed ID: 12727824
[TBL] [Abstract][Full Text] [Related]
12. Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
Lee M
Biochem Biophys Res Commun; 2006 Nov; 350(2):450-6. PubMed ID: 17010316
[TBL] [Abstract][Full Text] [Related]
13. Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB.
Vielma SA; Krings G; Lopes-Virella MF
Circ Res; 2003 May; 92(10):1130-7. PubMed ID: 12714566
[TBL] [Abstract][Full Text] [Related]
14. The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance.
Ehrhardt C; Rückle A; Hrincius ER; Haasbach E; Anhlan D; Ahmann K; Banning C; Reiling SJ; Kühn J; Strobl S; Vitt D; Leban J; Planz O; Ludwig S
Cell Microbiol; 2013 Jul; 15(7):1198-211. PubMed ID: 23320394
[TBL] [Abstract][Full Text] [Related]
15. Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.
Marampon F; Ciccarelli C; Zani BM
Mol Cancer; 2006 Aug; 5():31. PubMed ID: 16899113
[TBL] [Abstract][Full Text] [Related]
16. MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells.
Planz O; Pleschka S; Ludwig S
J Virol; 2001 May; 75(10):4871-7. PubMed ID: 11312358
[TBL] [Abstract][Full Text] [Related]
17. Development of cellular signaling pathway inhibitors as new antivirals against influenza.
Planz O
Antiviral Res; 2013 Jun; 98(3):457-68. PubMed ID: 23603495
[TBL] [Abstract][Full Text] [Related]
18. Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy.
Ludwig S; Planz O
Biol Chem; 2008 Oct; 389(10):1307-12. PubMed ID: 18713017
[TBL] [Abstract][Full Text] [Related]
19. Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity.
Mazur I; Wurzer WJ; Ehrhardt C; Pleschka S; Puthavathana P; Silberzahn T; Wolff T; Planz O; Ludwig S
Cell Microbiol; 2007 Jul; 9(7):1683-94. PubMed ID: 17324159
[TBL] [Abstract][Full Text] [Related]
20. Liu Shen Wan inhibits influenza a virus and excessive virus-induced inflammatory response via suppression of TLR4/NF-κB signaling pathway in vitro and in vivo.
Ma Q; Huang W; Zhao J; Yang Z
J Ethnopharmacol; 2020 Apr; 252():112584. PubMed ID: 31972325
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]