BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 21649464)

  • 1. The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy.
    Smith CC; Li B; Liu J; Lee KS; Aurelian L
    Cancer Invest; 2011 Jul; 29(6):383-95. PubMed ID: 21649464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-beta-activated kinase 1.
    Li B; Smith CC; Laing JM; Gober MD; Liu L; Aurelian L
    Oncogene; 2007 May; 26(24):3521-31. PubMed ID: 17173073
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells.
    Gober MD; Smith CC; Ueda K; Toretsky JA; Aurelian L
    J Biol Chem; 2003 Sep; 278(39):37600-9. PubMed ID: 12832417
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions.
    Sharma BK; Smith CC; Laing JM; Rucker DA; Burnett JW; Aurelian L
    Dermatology; 2006; 213(3):192-9. PubMed ID: 17033167
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways.
    Smith CC; Lee KS; Li B; Laing JM; Hersl J; Shvartsbeyn M; Aurelian L
    Cell Death Dis; 2012 Aug; 3(8):e371. PubMed ID: 22898869
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oncogenic DNA methyltransferase 1 activates the PI3K/AKT/mTOR signalling by blocking the binding of HSPB8 and BAG3 in melanoma.
    Yang Y; Ma S; Ye Z; Zheng Y; Zheng Z; Liu X; Zhou X
    Epigenetics; 2023 Dec; 18(1):2239607. PubMed ID: 37523636
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HSPB8 is methylated in hematopoietic malignancies and overexpression of HSPB8 exhibits antileukemia effect.
    Cui XY; Wang N; Yang BX; Gao WF; Lin YM; Yao XR; Ma XT
    Exp Hematol; 2012 Jan; 40(1):14-21. PubMed ID: 21914495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H11/HspB8 and Its Herpes Simplex Virus Type 2 Homologue ICP10PK Share Functions That Regulate Cell Life/Death Decisions and Human Disease.
    Aurelian L; Laing JM; Lee KS
    Autoimmune Dis; 2012; 2012():395329. PubMed ID: 23056924
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo.
    Alcazar O; Achberger S; Aldrich W; Hu Z; Negrotto S; Saunthararajah Y; Triozzi P
    Int J Cancer; 2012 Jul; 131(1):18-29. PubMed ID: 21796622
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.
    Rubinstein JC; Tran N; Ma S; Halaban R; Krauthammer M
    BMC Med Genomics; 2010 Feb; 3():4. PubMed ID: 20144234
    [TBL] [Abstract][Full Text] [Related]  

  • 11. S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth.
    Chuang JC; Warner SL; Vollmer D; Vankayalapati H; Redkar S; Bearss DJ; Qiu X; Yoo CB; Jones PA
    Mol Cancer Ther; 2010 May; 9(5):1443-50. PubMed ID: 20442312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thrombospondin-1 expression in melanoma is blocked by methylation and targeted reversal by 5-Aza-deoxycytidine suppresses angiogenesis.
    Lindner DJ; Wu Y; Haney R; Jacobs BS; Fruehauf JP; Tuthill R; Borden EC
    Matrix Biol; 2013 Mar; 32(2):123-32. PubMed ID: 23202046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of methylation-associated silencing of the death-associated protein kinase gene on nasopharyngeal carcinoma.
    Kong WJ; Zhang S; Guo CK; Wang YJ; Chen X; Zhang SL; Zhang D; Liu Z; Kong W
    Anticancer Drugs; 2006 Mar; 17(3):251-9. PubMed ID: 16520653
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications.
    Coral S; Sigalotti L; Colizzi F; Spessotto A; Nardi G; Cortini E; Pezzani L; Fratta E; Fonsatti E; Di Giacomo AM; Nicotra MR; Natali PG; Altomonte M; Maio M
    J Cell Physiol; 2006 Apr; 207(1):58-66. PubMed ID: 16252259
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TAp73 and ΔNp73 have opposing roles in 5-aza-2'-deoxycytidine-induced apoptosis in breast cancer cells.
    Lai J; Yang F; Zhang W; Wang Y; Xu J; Song W; Huang G; Gu J; Guan X
    Mol Cells; 2014 Aug; 37(8):605-12. PubMed ID: 25134538
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequent methylation of RASSF1A in synovial sarcoma and the anti-tumor effects of 5-aza-2'-deoxycytidine against synovial sarcoma cell lines.
    Numoto K; Yoshida A; Sugihara S; Kunisada T; Morimoto Y; Yoneda Y; Fujita Y; Nishida K; Ouchida M; Ozaki T
    J Cancer Res Clin Oncol; 2010 Jan; 136(1):17-25. PubMed ID: 19578875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Inhibitory effect of 5-Aza-2'-deoxycytidine on human nasopharyngeal carcinoma xenograft in nude mice].
    Zhang S; Kong WJ; Wang YJ; Han YC; Zhang D
    Ai Zheng; 2005 Oct; 24(10):1201-5. PubMed ID: 16219133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.
    Widodo N; Deocaris CC; Kaur K; Hasan K; Yaguchi T; Yamasaki K; Sugihara T; Ishii T; Wadhwa R; Kaul SC
    J Gerontol A Biol Sci Med Sci; 2007 Mar; 62(3):246-55. PubMed ID: 17389721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.
    Reu FJ; Bae SI; Cherkassky L; Leaman DW; Lindner D; Beaulieu N; MacLeod AR; Borden EC
    J Clin Oncol; 2006 Aug; 24(23):3771-9. PubMed ID: 16801630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [5-aza-2'-deoxycytidine-induced inhibition of CDH13 expression and its inhibitory effect on methylation status in human colon cancer cells in vitro and on growth of xenograft in nude mice].
    Ren JZ; Huo JR
    Zhonghua Zhong Liu Za Zhi; 2012 Jan; 34(1):6-10. PubMed ID: 22490847
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.