These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 21651478)

  • 1. Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication.
    Garbelli A; Radi M; Falchi F; Beermann S; Zanoli S; Manetti F; Dietrich U; Botta M; Maga G
    Curr Med Chem; 2011; 18(20):3015-27. PubMed ID: 21651478
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors.
    Radi M; Falchi F; Garbelli A; Samuele A; Bernardo V; Paolucci S; Baldanti F; Schenone S; Manetti F; Maga G; Botta M
    Bioorg Med Chem Lett; 2012 Mar; 22(5):2094-8. PubMed ID: 22300661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs.
    Kukhanova MK; Karpenko IL; Ivanov AV
    Molecules; 2020 Feb; 25(4):. PubMed ID: 32102413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors.
    Fazi R; Tintori C; Brai A; Botta L; Selvaraj M; Garbelli A; Maga G; Botta M
    J Chem Inf Model; 2015 Nov; 55(11):2443-54. PubMed ID: 26544088
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?
    Garbelli A; Riva V; Crespan E; Maga G
    Biochem J; 2017 Apr; 474(10):1559-1577. PubMed ID: 28446620
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication.
    Garbelli A; Beermann S; Di Cicco G; Dietrich U; Maga G
    PLoS One; 2011 May; 6(5):e19810. PubMed ID: 21589879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Ded1/DDX3 subfamily of DEAD-box RNA helicases.
    Sharma D; Jankowsky E
    Crit Rev Biochem Mol Biol; 2014; 49(4):343-60. PubMed ID: 25039764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toward the discovery of novel anti-HIV drugs. Second-generation inhibitors of the cellular ATPase DDX3 with improved anti-HIV activity: synthesis, structure-activity relationship analysis, cytotoxicity studies, and target validation.
    Maga G; Falchi F; Radi M; Botta L; Casaluce G; Bernardini M; Irannejad H; Manetti F; Garbelli A; Samuele A; Zanoli S; Esté JA; Gonzalez E; Zucca E; Paolucci S; Baldanti F; De Rijck J; Debyser Z; Botta M
    ChemMedChem; 2011 Aug; 6(8):1371-89. PubMed ID: 21698775
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain.
    Fröhlich A; Rojas-Araya B; Pereira-Montecinos C; Dellarossa A; Toro-Ascuy D; Prades-Pérez Y; García-de-Gracia F; Garcés-Alday A; Rubilar PS; Valiente-Echeverría F; Ohlmann T; Soto-Rifo R
    Biochim Biophys Acta; 2016 May; 1859(5):719-30. PubMed ID: 27012366
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function.
    Yedavalli VS; Neuveut C; Chi YH; Kleiman L; Jeang KT
    Cell; 2004 Oct; 119(3):381-92. PubMed ID: 15507209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity.
    Valiente-Echeverría F; Hermoso MA; Soto-Rifo R
    Rev Med Virol; 2015 Sep; 25(5):286-99. PubMed ID: 26174373
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DDX3 RNA helicase is required for HIV-1 Tat function.
    Yasuda-Inoue M; Kuroki M; Ariumi Y
    Biochem Biophys Res Commun; 2013 Nov; 441(3):607-11. PubMed ID: 24183723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism.
    Soto-Rifo R; Ohlmann T
    Wiley Interdiscip Rev RNA; 2013; 4(4):369-85. PubMed ID: 23606618
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication.
    Ariumi Y; Kuroki M; Abe K; Dansako H; Ikeda M; Wakita T; Kato N
    J Virol; 2007 Dec; 81(24):13922-6. PubMed ID: 17855521
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cycle.
    Mahboobi SH; Javanpour AA; Mofrad MR
    PLoS One; 2015; 10(2):e0112969. PubMed ID: 25723178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.
    Brai A; Fazi R; Tintori C; Zamperini C; Bugli F; Sanguinetti M; Stigliano E; Esté J; Badia R; Franco S; Martinez MA; Martinez JP; Meyerhans A; Saladini F; Zazzi M; Garbelli A; Maga G; Botta M
    Proc Natl Acad Sci U S A; 2016 May; 113(19):5388-93. PubMed ID: 27118832
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analog sensitive chemical inhibition of the DEAD-box protein DDX3.
    Floor SN; Barkovich KJ; Condon KJ; Shokat KM; Doudna JA
    Protein Sci; 2016 Mar; 25(3):638-49. PubMed ID: 26650549
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A method to study the role of DDX3 RNA helicase in HIV-1.
    Chen CY; Yedavalli VR; Jeang KT
    Methods Mol Biol; 2010; 587():281-9. PubMed ID: 20225157
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Knockdown of cellular RNA helicase DDX3 by short hairpin RNAs suppresses HIV-1 viral replication without inducing apoptosis.
    Ishaq M; Hu J; Wu X; Fu Q; Yang Y; Liu Q; Guo D
    Mol Biotechnol; 2008 Jul; 39(3):231-8. PubMed ID: 18259889
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DDX3 DEAD-Box RNA helicase inhibits hepatitis B virus reverse transcription by incorporation into nucleocapsids.
    Wang H; Kim S; Ryu WS
    J Virol; 2009 Jun; 83(11):5815-24. PubMed ID: 19297497
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.