BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 21653687)

  • 1. Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway.
    Toh YM; Li TK
    Clin Cancer Res; 2011 Aug; 17(15):5026-37. PubMed ID: 21653687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
    Creighton-Gutteridge M; Cardellina JH; Stephen AG; Rapisarda A; Uranchimeg B; Hite K; Denny WA; Shoemaker RH; Melillo G
    Clin Cancer Res; 2007 Feb; 13(3):1010-8. PubMed ID: 17289897
    [TBL] [Abstract][Full Text] [Related]  

  • 3. UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway.
    Rapisarda A; Melillo G
    Oncogene; 2007 Oct; 26(48):6875-84. PubMed ID: 17496931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. D-glucosamine down-regulates HIF-1alpha through inhibition of protein translation in DU145 prostate cancer cells.
    Park JY; Park JW; Suh SI; Baek WK
    Biochem Biophys Res Commun; 2009 Apr; 382(1):96-101. PubMed ID: 19254699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Silibinin inhibits expression of HIF-1alpha through suppression of protein translation in prostate cancer cells.
    Jung HJ; Park JW; Lee JS; Lee SR; Jang BC; Suh SI; Suh MH; Baek WK
    Biochem Biophys Res Commun; 2009 Dec; 390(1):71-6. PubMed ID: 19778521
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition.
    Dai M; Miao ZH; Ren X; Tong LJ; Yang N; Li T; Lin LP; Shen YM; Ding J
    J Cell Mol Med; 2010 Sep; 14(9):2281-91. PubMed ID: 19538463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: a novel function for an old drug.
    Newcomb EW; Lukyanov Y; Schnee T; Ali MA; Lan L; Zagzag D
    Int J Oncol; 2006 May; 28(5):1121-30. PubMed ID: 16596228
    [TBL] [Abstract][Full Text] [Related]  

  • 8. siRNA targeting HIF-1alpha induces apoptosis of pancreatic cancer cells through NF-kappaB-independent and -dependent pathways under hypoxic conditions.
    Chen C; Yu Z
    Anticancer Res; 2009 Apr; 29(4):1367-72. PubMed ID: 19414389
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tocotrienol inhibits secretion of angiogenic factors from human colorectal adenocarcinoma cells by suppressing hypoxia-inducible factor-1alpha.
    Shibata A; Nakagawa K; Sookwong P; Tsuduki T; Tomita S; Shirakawa H; Komai M; Miyazawa T
    J Nutr; 2008 Nov; 138(11):2136-42. PubMed ID: 18936210
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
    Chau NM; Rogers P; Aherne W; Carroll V; Collins I; McDonald E; Workman P; Ashcroft M
    Cancer Res; 2005 Jun; 65(11):4918-28. PubMed ID: 15930314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression levels and significance of hypoxia inducible factor-1 alpha and vascular endothelial growth factor in human colorectal adenocarcinoma.
    Jiang CQ; Fan LF; Liu ZS; Qian Q; Xia D; Diao LM; He YM; Ai ZL
    Chin Med J (Engl); 2004 Oct; 117(10):1541-6. PubMed ID: 15498380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells.
    Zhao Q; Du J; Gu H; Teng X; Zhang Q; Qin H; Liu N
    Pancreas; 2007 Mar; 34(2):242-7. PubMed ID: 17312464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene.
    Song X; Liu X; Chi W; Liu Y; Wei L; Wang X; Yu J
    Cancer Chemother Pharmacol; 2006 Dec; 58(6):776-84. PubMed ID: 16532342
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers.
    Bobarykina AY; Minchenko DO; Opentanova IL; Moenner M; Caro J; Esumi H; Minchenko OH
    Acta Biochim Pol; 2006; 53(4):789-99. PubMed ID: 17143338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells.
    Mirzoeva S; Kim ND; Chiu K; Franzen CA; Bergan RC; Pelling JC
    Mol Carcinog; 2008 Sep; 47(9):686-700. PubMed ID: 18240292
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of geldanamycin on HIF-1alpha mediated angiogenesis and invasion in prostate cancer cells.
    Alqawi O; Moghaddas M; Singh G
    Prostate Cancer Prostatic Dis; 2006; 9(2):126-35. PubMed ID: 16432534
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulating the hypoxia-inducible factor signaling pathway as a therapeutic modality to regulate retinal angiogenesis.
    DeNiro M; Alsmadi O; Al-Mohanna F
    Exp Eye Res; 2009 Nov; 89(5):700-17. PubMed ID: 19580810
    [TBL] [Abstract][Full Text] [Related]  

  • 18. KNK437, abrogates hypoxia-induced radioresistance by dual targeting of the AKT and HIF-1α survival pathways.
    Oommen D; Prise KM
    Biochem Biophys Res Commun; 2012 May; 421(3):538-43. PubMed ID: 22521642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Impact of RNA interference targeting hypoxia-inducible factor-1alpha on chemosensitivity in esophageal squamous cell carcinoma cells under hypoxia].
    Wu XA; Sun Y; Fan QX; Wang LX; Wang RL; Zhang L
    Zhonghua Yi Xue Za Zhi; 2007 Oct; 87(37):2640-4. PubMed ID: 18162154
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.
    Menendez JA; Vellon L; Oza BP; Lupu R
    J Cell Biochem; 2005 Apr; 94(5):857-63. PubMed ID: 15669079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.