These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts. Lal B; Goodwin CR; Sang Y; Foss CA; Cornet K; Muzamil S; Pomper MG; Kim J; Laterra J Mol Cancer Ther; 2009 Jul; 8(7):1751-60. PubMed ID: 19584231 [TBL] [Abstract][Full Text] [Related]
3. Interactions between PTEN and the c-Met pathway in glioblastoma and implications for therapy. Li Y; Guessous F; DiPierro C; Zhang Y; Mudrick T; Fuller L; Johnson E; Marcinkiewicz L; Engelhardt M; Kefas B; Schiff D; Kim J; Abounader R Mol Cancer Ther; 2009 Feb; 8(2):376-85. PubMed ID: 19190120 [TBL] [Abstract][Full Text] [Related]
5. PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuroblastoma cells. Crosswell HE; Dasgupta A; Alvarado CS; Watt T; Christensen JG; De P; Durden DL; Findley HW BMC Cancer; 2009 Nov; 9():411. PubMed ID: 19939254 [TBL] [Abstract][Full Text] [Related]
6. Identification of the receptor tyrosine kinase c-Met and its ligand, hepatocyte growth factor, as therapeutic targets in clear cell sarcoma. Davis IJ; McFadden AW; Zhang Y; Coxon A; Burgess TL; Wagner AJ; Fisher DE Cancer Res; 2010 Jan; 70(2):639-45. PubMed ID: 20068147 [TBL] [Abstract][Full Text] [Related]
7. A novel lead compound CM-118: antitumor activity and new insight into the molecular mechanism and combination therapy strategy in c-Met- and ALK-dependent cancers. Meng L; Shu M; Chen Y; Yang D; He Q; Zhao H; Feng Z; Liang C; Yu K Cancer Biol Ther; 2014 Jun; 15(6):721-34. PubMed ID: 24618813 [TBL] [Abstract][Full Text] [Related]
8. Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma. Koul D; Wang S; Wu S; Saito N; Zheng S; Gao F; Kaul I; Setoguchi M; Nakayama K; Koyama K; Shiose Y; Sulman EP; Hirota Y; Yung WKA Oncotarget; 2017 Mar; 8(13):21741-21753. PubMed ID: 28423515 [TBL] [Abstract][Full Text] [Related]
9. The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases. Pillay V; Allaf L; Wilding AL; Donoghue JF; Court NW; Greenall SA; Scott AM; Johns TG Neoplasia; 2009 May; 11(5):448-58, 2 p following 458. PubMed ID: 19412429 [TBL] [Abstract][Full Text] [Related]
10. HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma. Bu R; Uddin S; Bavi P; Hussain AR; Al-Dayel F; Ghourab S; Ahmed M; Al-Kuraya KS Lab Invest; 2011 Jan; 91(1):124-37. PubMed ID: 20661229 [TBL] [Abstract][Full Text] [Related]
11. Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma. Kenessey I; Keszthelyi M; Krámer Z; Berta J; Adám A; Dobos J; Mildner M; Flachner B; Cseh S; Barna G; Szokol B; Orfi L; Kéri G; Döme B; Klepetko W; Tímár J; Tóvári J Curr Cancer Drug Targets; 2010 May; 10(3):332-42. PubMed ID: 20370683 [TBL] [Abstract][Full Text] [Related]
12. Combinatorial therapy with adenoviral-mediated PTEN and a PI3K inhibitor suppresses malignant glioma cell growth in vitro and in vivo by regulating the PI3K/AKT signaling pathway. Nan Y; Guo L; Song Y; Wang L; Yu K; Huang Q; Zhong Y J Cancer Res Clin Oncol; 2017 Aug; 143(8):1477-1487. PubMed ID: 28401302 [TBL] [Abstract][Full Text] [Related]
13. HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer. Knowles LM; Stabile LP; Egloff AM; Rothstein ME; Thomas SM; Gubish CT; Lerner EC; Seethala RR; Suzuki S; Quesnelle KM; Morgan S; Ferris RL; Grandis JR; Siegfried JM Clin Cancer Res; 2009 Jun; 15(11):3740-50. PubMed ID: 19470725 [TBL] [Abstract][Full Text] [Related]
14. MAGI3 Suppresses Glioma Cell Proliferation via Upregulation of PTEN Expression. Ma Q; Zhang Y; Meng R; Xie KM; Xiong Y; Lin S; He ZL; Tao T; Yang Y; Zhao JZ; He JQ Biomed Environ Sci; 2015 Jul; 28(7):502-9. PubMed ID: 26248734 [TBL] [Abstract][Full Text] [Related]
15. Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells. Xu H; Stabile LP; Gubish CT; Gooding WE; Grandis JR; Siegfried JM Clin Cancer Res; 2011 Jul; 17(13):4425-38. PubMed ID: 21622718 [TBL] [Abstract][Full Text] [Related]
16. Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts. Kim KJ; Wang L; Su YC; Gillespie GY; Salhotra A; Lal B; Laterra J Clin Cancer Res; 2006 Feb; 12(4):1292-8. PubMed ID: 16489086 [TBL] [Abstract][Full Text] [Related]
17. A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. Christensen JG; Schreck R; Burrows J; Kuruganti P; Chan E; Le P; Chen J; Wang X; Ruslim L; Blake R; Lipson KE; Ramphal J; Do S; Cui JJ; Cherrington JM; Mendel DB Cancer Res; 2003 Nov; 63(21):7345-55. PubMed ID: 14612533 [TBL] [Abstract][Full Text] [Related]
18. Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer. Takeuchi S; Wang W; Li Q; Yamada T; Kita K; Donev IS; Nakamura T; Matsumoto K; Shimizu E; Nishioka Y; Sone S; Nakagawa T; Uenaka T; Yano S Am J Pathol; 2012 Sep; 181(3):1034-43. PubMed ID: 22789825 [TBL] [Abstract][Full Text] [Related]
19. Norcantharidin combined with EGFR-TKIs overcomes HGF-induced resistance to EGFR-TKIs in EGFR mutant lung cancer cells via inhibition of Met/PI3k/Akt pathway. Wu H; Fan F; Liu Z; Shen C; Wang A; Lu Y Cancer Chemother Pharmacol; 2015 Aug; 76(2):307-15. PubMed ID: 26063323 [TBL] [Abstract][Full Text] [Related]
20. Combining onartuzumab with erlotinib inhibits growth of non-small cell lung cancer with activating EGFR mutations and HGF overexpression. Sano Y; Hashimoto E; Nakatani N; Abe M; Satoh Y; Sakata K; Fujii T; Fujimoto-Ouchi K; Sugimoto M; Nagahashi S; Aoki M; Motegi H; Sasaki E; Yatabe Y Mol Cancer Ther; 2015 Feb; 14(2):533-41. PubMed ID: 25522765 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]