BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

666 related articles for article (PubMed ID: 21659424)

  • 1. Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
    Hinoue T; Weisenberger DJ; Lange CP; Shen H; Byun HM; Van Den Berg D; Malik S; Pan F; Noushmehr H; van Dijk CM; Tollenaar RA; Laird PW
    Genome Res; 2012 Feb; 22(2):271-82. PubMed ID: 21659424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features.
    Ang PW; Loh M; Liem N; Lim PL; Grieu F; Vaithilingam A; Platell C; Yong WP; Iacopetta B; Soong R
    BMC Cancer; 2010 May; 10():227. PubMed ID: 20492682
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
    Suehiro Y; Wong CW; Chirieac LR; Kondo Y; Shen L; Webb CR; Chan YW; Chan AS; Chan TL; Wu TT; Rashid A; Hamanaka Y; Hinoda Y; Shannon RL; Wang X; Morris J; Issa JP; Yuen ST; Leung SY; Hamilton SR
    Clin Cancer Res; 2008 May; 14(9):2560-9. PubMed ID: 18451217
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.
    Hinoue T; Weisenberger DJ; Pan F; Campan M; Kim M; Young J; Whitehall VL; Leggett BA; Laird PW
    PLoS One; 2009 Dec; 4(12):e8357. PubMed ID: 20027224
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer.
    Nagasaka T; Koi M; Kloor M; Gebert J; Vilkin A; Nishida N; Shin SK; Sasamoto H; Tanaka N; Matsubara N; Boland CR; Goel A
    Gastroenterology; 2008 Jun; 134(7):1950-60, 1960.e1. PubMed ID: 18435933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
    Dawson H; Galván JA; Helbling M; Muller DE; Karamitopoulou E; Koelzer VH; Economou M; Hammer C; Lugli A; Zlobec I
    Int J Cancer; 2014 May; 134(10):2342-51. PubMed ID: 24166180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.
    Yamamoto E; Suzuki H; Yamano HO; Maruyama R; Nojima M; Kamimae S; Sawada T; Ashida M; Yoshikawa K; Kimura T; Takagi R; Harada T; Suzuki R; Sato A; Kai M; Sasaki Y; Tokino T; Sugai T; Imai K; Shinomura Y; Toyota M
    Am J Pathol; 2012 Nov; 181(5):1847-61. PubMed ID: 22995252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation.
    Lee S; Cho NY; Choi M; Yoo EJ; Kim JH; Kang GH
    Pathol Int; 2008 Feb; 58(2):104-13. PubMed ID: 18199160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
    Ogino S; Kawasaki T; Kirkner GJ; Ogawa A; Dorfman I; Loda M; Fuchs CS
    J Pathol; 2006 Oct; 210(2):147-54. PubMed ID: 16850502
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.
    Ogino S; Kawasaki T; Kirkner GJ; Loda M; Fuchs CS
    J Mol Diagn; 2006 Nov; 8(5):582-8. PubMed ID: 17065427
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas.
    Fennell L; Dumenil T; Wockner L; Hartel G; Nones K; Bond C; Borowsky J; Liu C; McKeone D; Bowdler L; Montgomery G; Klein K; Hoffmann I; Patch AM; Kazakoff S; Pearson J; Waddell N; Wirapati P; Lochhead P; Imamura Y; Ogino S; Shao R; Tejpar S; Leggett B; Whitehall V
    Cell Mol Gastroenterol Hepatol; 2019; 8(2):269-290. PubMed ID: 30954552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas.
    Kim JC; Choi JS; Roh SA; Cho DH; Kim TW; Kim YS
    Ann Surg Oncol; 2010 Jul; 17(7):1767-76. PubMed ID: 20077021
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
    de Vogel S; Weijenberg MP; Herman JG; Wouters KA; de Goeij AF; van den Brandt PA; de Bruïne AP; van Engeland M
    Ann Oncol; 2009 Jul; 20(7):1216-22. PubMed ID: 19164452
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple sporadic colorectal cancers display a unique methylation phenotype.
    Gonzalo V; Lozano JJ; Alonso-Espinaco V; Moreira L; Muñoz J; Pellisé M; Castellví-Bel S; Bessa X; Andreu M; Xicola RM; Llor X; Ruiz-Ponte C; Carracedo A; Jover R; Castells A; Balaguer F;
    PLoS One; 2014; 9(3):e91033. PubMed ID: 24643221
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers.
    Olaru AV; Cheng Y; Agarwal R; Yang J; David S; Abraham JM; Yu W; Kwon JH; Lazarev M; Brant SR; Marohn MR; Hutcheon DF; Harpaz N; Meltzer SJ; Mori Y
    Inflamm Bowel Dis; 2012 Apr; 18(4):641-8. PubMed ID: 21830278
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
    Naghibalhossaini F; Hosseini HM; Mokarram P; Zamani M
    Pathol Oncol Res; 2011 Dec; 17(4):819-25. PubMed ID: 21455633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rectal cancer profiling identifies distinct subtypes in India based on age at onset, genetic, epigenetic and clinicopathological characteristics.
    Laskar RS; Ghosh SK; Talukdar FR
    Mol Carcinog; 2015 Dec; 54(12):1786-95. PubMed ID: 25418895
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.
    Karpinski P; Ramsey D; Grzebieniak Z; Sasiadek MM; Blin N
    Mol Cancer Res; 2008 Apr; 6(4):585-91. PubMed ID: 18403637
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
    Tanaka N; Huttenhower C; Nosho K; Baba Y; Shima K; Quackenbush J; Haigis KM; Giovannucci E; Fuchs CS; Ogino S
    Am J Pathol; 2010 Dec; 177(6):2731-40. PubMed ID: 21037082
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
    Shima K; Morikawa T; Baba Y; Nosho K; Suzuki M; Yamauchi M; Hayashi M; Giovannucci E; Fuchs CS; Ogino S
    Cancer Causes Control; 2011 Feb; 22(2):301-9. PubMed ID: 21140203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.