These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 21659511)

  • 1. Distribution and biochemical properties of an M1-family aminopeptidase in Plasmodium falciparum indicate a role in vacuolar hemoglobin catabolism.
    Ragheb D; Dalal S; Bompiani KM; Ray WK; Klemba M
    J Biol Chem; 2011 Aug; 286(31):27255-65. PubMed ID: 21659511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole.
    Azimzadeh O; Sow C; Gèze M; Nyalwidhe J; Florent I
    Malar J; 2010 Jun; 9():189. PubMed ID: 20591164
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for catalytic roles for Plasmodium falciparum aminopeptidase P in the food vacuole and cytosol.
    Ragheb D; Bompiani K; Dalal S; Klemba M
    J Biol Chem; 2009 Sep; 284(37):24806-15. PubMed ID: 19574214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Engagement of the S1, S1' and S2' subsites drives efficient catalysis of peptide bond hydrolysis by the M1-family aminopeptidase from Plasmodium falciparum.
    Dalal S; Ragheb DR; Klemba M
    Mol Biochem Parasitol; 2012 May; 183(1):70-7. PubMed ID: 22348949
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum.
    Dalal S; Klemba M
    J Biol Chem; 2007 Dec; 282(49):35978-87. PubMed ID: 17895246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Properties, stage-dependent expression and localization of Plasmodium falciparum M1 family zinc-aminopeptidase.
    Allary M; Schrevel J; Florent I
    Parasitology; 2002 Jul; 125(Pt 1):1-10. PubMed ID: 12166515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation.
    Klemba M; Gluzman I; Goldberg DE
    J Biol Chem; 2004 Oct; 279(41):43000-7. PubMed ID: 15304495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic and chemical validation of
    Edgar RCS; Siddiqui G; Hjerrild K; Malcolm TR; Vinh NB; Webb CT; Holmes C; MacRaild CA; Chernih HC; Suen WW; Counihan NA; Creek DJ; Scammells PJ; McGowan S; de Koning-Ward TF
    Elife; 2022 Sep; 11():. PubMed ID: 36097817
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two cap residues in the S1 subsite of a Plasmodium falciparum M1-family aminopeptidase promote broad specificity and enhance catalysis.
    Rosati M; Dalal S; Klemba M
    Mol Biochem Parasitol; 2017 Oct; 217():7-12. PubMed ID: 28811124
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of aminopeptidases in haemoglobin degradation in Plasmodium falciparum-infected erythrocytes.
    Gavigan CS; Dalton JP; Bell A
    Mol Biochem Parasitol; 2001 Sep; 117(1):37-48. PubMed ID: 11551630
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases.
    McGowan S; Oellig CA; Birru WA; Caradoc-Davies TT; Stack CM; Lowther J; Skinner-Adams T; Mucha A; Kafarski P; Grembecka J; Trenholme KR; Buckle AM; Gardiner DL; Dalton JP; Whisstock JC
    Proc Natl Acad Sci U S A; 2010 Feb; 107(6):2449-54. PubMed ID: 20133789
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases.
    Harbut MB; Velmourougane G; Dalal S; Reiss G; Whisstock JC; Onder O; Brisson D; McGowan S; Klemba M; Greenbaum DC
    Proc Natl Acad Sci U S A; 2011 Aug; 108(34):E526-34. PubMed ID: 21844374
    [TBL] [Abstract][Full Text] [Related]  

  • 13. KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
    González-Bacerio J; Maluf SEC; Méndez Y; Pascual I; Florent I; Melo PMS; Budu A; Ferreira JC; Moreno E; Carmona AK; Rivera DG; Alonso Del Rivero M; Gazarini ML
    Bioorg Med Chem; 2017 Sep; 25(17):4628-4636. PubMed ID: 28728898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A naturally variable residue in the S1 subsite of M1 family aminopeptidases modulates catalytic properties and promotes functional specialization.
    Dalal S; Ragheb DRT; Schubot FD; Klemba M
    J Biol Chem; 2013 Sep; 288(36):26004-26012. PubMed ID: 23897806
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1.
    Yang W; Riley BT; Lei X; Porebski BT; Kass I; Buckle AM; McGowan S
    ChemMedChem; 2018 Dec; 13(23):2504-2513. PubMed ID: 30318749
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum.
    Teuscher F; Lowther J; Skinner-Adams TS; Spielmann T; Dixon MW; Stack CM; Donnelly S; Mucha A; Kafarski P; Vassiliou S; Gardiner DL; Dalton JP; Trenholme KR
    J Biol Chem; 2007 Oct; 282(42):30817-26. PubMed ID: 17720817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo.
    Bounaadja L; Schmitt M; Albrecht S; Mouray E; Tarnus C; Florent I
    Malar J; 2017 Sep; 16(1):382. PubMed ID: 28934959
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IgG antibody response against Plasmodium falciparum aminopeptidase 1 antigen in Gabonese children living in Makokou and Franceville.
    Oyegue-Liabagui SL; Imboumy-Limoukou RK; Kouna CL; Bangueboussa F; Schmitt M; Florent I; Lekana-Douki JB
    Clin Exp Immunol; 2020 Jun; 200(3):287-298. PubMed ID: 32027020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Plasmepsin II, an acidic hemoglobinase from the Plasmodium falciparum food vacuole, is active at neutral pH on the host erythrocyte membrane skeleton.
    Le Bonniec S; Deregnaucourt C; Redeker V; Banerjee R; Grellier P; Goldberg DE; Schrével J
    J Biol Chem; 1999 May; 274(20):14218-23. PubMed ID: 10318841
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations.
    Jones PM; Robinson MW; Dalton JP; George AM
    PLoS One; 2011; 6(12):e28589. PubMed ID: 22205955
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.