188 related articles for article (PubMed ID: 21665470)
1. Inhibition of a prolyl hydroxylase domain (PHD) by substrate analog peptides.
Kwon HS; Choi YK; Kim JW; Park YK; Yang EG; Ahn DR
Bioorg Med Chem Lett; 2011 Jul; 21(14):4325-8. PubMed ID: 21665470
[TBL] [Abstract][Full Text] [Related]
2. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
Hewitson KS; Schofield CJ; Ratcliffe PJ
Methods Enzymol; 2007; 435():25-42. PubMed ID: 17998047
[TBL] [Abstract][Full Text] [Related]
3. Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites.
Pappalardi MB; McNulty DE; Martin JD; Fisher KE; Jiang Y; Burns MC; Zhao H; Ho T; Sweitzer S; Schwartz B; Annan RS; Copeland RA; Tummino PJ; Luo L
Biochem J; 2011 Jun; 436(2):363-9. PubMed ID: 21410436
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of the catalytic activity of hypoxia-inducible factor-1alpha-prolyl-hydroxylase 2 by a MYND-type zinc finger.
Choi KO; Lee T; Lee N; Kim JH; Yang EG; Yoon JM; Kim JH; Lee TG; Park H
Mol Pharmacol; 2005 Dec; 68(6):1803-9. PubMed ID: 16155211
[TBL] [Abstract][Full Text] [Related]
5. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
[TBL] [Abstract][Full Text] [Related]
6. Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases.
Lee MJ; Kim JW; Yang EG
Biochem Biophys Res Commun; 2010 May; 396(2):370-5. PubMed ID: 20416277
[TBL] [Abstract][Full Text] [Related]
7. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH).
Flagg SC; Martin CB; Taabazuing CY; Holmes BE; Knapp MJ
J Inorg Biochem; 2012 Aug; 113():25-30. PubMed ID: 22687491
[TBL] [Abstract][Full Text] [Related]
8. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.
Spinella F; Rosanò L; Del Duca M; Di Castro V; Nicotra MR; Natali PG; Bagnato A
PLoS One; 2010 Jun; 5(6):e11241. PubMed ID: 20574527
[TBL] [Abstract][Full Text] [Related]
9. Effects of polynitrogen compounds on the activity of recombinant human HIF-1α prolyl hydroxylase 3 in E. coli.
Geng Z; Zhu J; Cao J; Geng J; Song X; Zhang Z; Bian N; Wang Z
J Inorg Biochem; 2011 Mar; 105(3):391-9. PubMed ID: 21421125
[TBL] [Abstract][Full Text] [Related]
10. HIF-prolyl hydroxylases and cardiovascular diseases.
Sen Banerjee S; Thirunavukkarasu M; Tipu Rishi M; Sanchez JA; Maulik N; Maulik G
Toxicol Mech Methods; 2012 Jun; 22(5):347-58. PubMed ID: 22424133
[TBL] [Abstract][Full Text] [Related]
11. Dipeptidyl-quinolone derivatives inhibit hypoxia inducible factor-1α prolyl hydroxylases-1, -2, and -3 with altered selectivity.
Murray JK; Balan C; Allgeier AM; Kasparian A; Viswanadhan V; Wilde C; Allen JR; Yoder SC; Biddlecome G; Hungate RW; Miranda LP
J Comb Chem; 2010 Sep; 12(5):676-86. PubMed ID: 20666436
[TBL] [Abstract][Full Text] [Related]
12. Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors.
Tug S; Delos Reyes B; Fandrey J; Berchner-Pfannschmidt U
Biochem Biophys Res Commun; 2009 Jul; 384(4):519-23. PubMed ID: 19427832
[TBL] [Abstract][Full Text] [Related]
13. A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia.
Nangaku M; Izuhara Y; Takizawa S; Yamashita T; Fujii-Kuriyama Y; Ohneda O; Yamamoto M; van Ypersele de Strihou C; Hirayama N; Miyata T
Arterioscler Thromb Vasc Biol; 2007 Dec; 27(12):2548-54. PubMed ID: 17932321
[TBL] [Abstract][Full Text] [Related]
14. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury.
Natarajan R; Salloum FN; Fisher BJ; Kukreja RC; Fowler AA
Circ Res; 2006 Jan; 98(1):133-40. PubMed ID: 16306444
[TBL] [Abstract][Full Text] [Related]
15. Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases.
Kanelakis KC; Palomino HL; Li L; Wu J; Yan W; Rosen MD; Rizzolio MC; Trivedi M; Morton MF; Yang Y; Venkatesan H; Rabinowitz MH; Shankley NP; Barrett TD
J Biomol Screen; 2009 Jul; 14(6):627-35. PubMed ID: 19498081
[TBL] [Abstract][Full Text] [Related]
16. The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
Barth S; Nesper J; Hasgall PA; Wirthner R; Nytko KJ; Edlich F; Katschinski DM; Stiehl DP; Wenger RH; Camenisch G
Mol Cell Biol; 2007 May; 27(10):3758-68. PubMed ID: 17353276
[TBL] [Abstract][Full Text] [Related]
17. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
[TBL] [Abstract][Full Text] [Related]
18. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
19. A fluorescence polarization-based interaction assay for hypoxia-inducible factor prolyl hydroxylases.
Cho H; Park H; Yang EG
Biochem Biophys Res Commun; 2005 Nov; 337(1):275-80. PubMed ID: 16182243
[TBL] [Abstract][Full Text] [Related]
20. Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions.
Floyd ZE; Kilroy G; Wu X; Gimble JM
J Cell Biochem; 2007 Aug; 101(6):1545-57. PubMed ID: 17370314
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]