These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

443 related articles for article (PubMed ID: 21666678)

  • 1. An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity.
    Guo W; Chen Y; Zhou X; Kar A; Ray P; Chen X; Rao EJ; Yang M; Ye H; Zhu L; Liu J; Xu M; Yang Y; Wang C; Zhang D; Bigio EH; Mesulam M; Shen Y; Xu Q; Fushimi K; Wu JY
    Nat Struct Mol Biol; 2011 Jun; 18(7):822-30. PubMed ID: 21666678
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of β-domains in C-terminal fragments of TDP-43 by scanning tunneling microscopy.
    Xu M; Zhu L; Liu J; Yang Y; Wu JY; Wang C
    J Struct Biol; 2013 Jan; 181(1):11-6. PubMed ID: 23138004
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.
    Shimonaka S; Nonaka T; Suzuki G; Hisanaga S; Hasegawa M
    J Biol Chem; 2016 Apr; 291(17):8896-907. PubMed ID: 26887947
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.
    Pesiridis GS; Lee VM; Trojanowski JQ
    Hum Mol Genet; 2009 Oct; 18(R2):R156-62. PubMed ID: 19808791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
    Ke YD; van Hummel A; Stevens CH; Gladbach A; Ippati S; Bi M; Lee WS; Krüger S; van der Hoven J; Volkerling A; Bongers A; Halliday G; Haass NK; Kiernan M; Delerue F; Ittner LM
    Acta Neuropathol; 2015 Nov; 130(5):661-78. PubMed ID: 26437864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Implications of the prion-related Q/N domains in TDP-43 and FUS.
    Udan M; Baloh RH
    Prion; 2011; 5(1):1-5. PubMed ID: 21135580
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel TARDBP mutation in an Australian amyotrophic lateral sclerosis kindred.
    Williams KL; Durnall JC; Thoeng AD; Warraich ST; Nicholson GA; Blair IP
    J Neurol Neurosurg Psychiatry; 2009 Nov; 80(11):1286-8. PubMed ID: 19864664
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the Mutation.
    Wang X; Zhou S; Ding X; Ma M; Zhang J; Zhou Y; Wu E; Teng J
    Int J Biol Sci; 2015; 11(10):1140-9. PubMed ID: 26327808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A90V TDP-43 variant results in the aberrant localization of TDP-43 in vitro.
    Winton MJ; Van Deerlin VM; Kwong LK; Yuan W; Wood EM; Yu CE; Schellenberg GD; Rademakers R; Caselli R; Karydas A; Trojanowski JQ; Miller BL; Lee VM
    FEBS Lett; 2008 Jun; 582(15):2252-6. PubMed ID: 18505686
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [TDP-43 proteinopathies: ALS and frontotemporal dementias].
    Prudlo J
    Fortschr Neurol Psychiatr; 2009 Aug; 77 Suppl 1():S25-7. PubMed ID: 19685386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [FTLD/ALS as TDP-43 proteinopathies].
    Ishihara T; Ariizumi Y; Shiga A; Yokoseki A; Sato T; Toyoshima Y; Kakita A; Takahashi H; Nishizawa M; Onodera O
    Rinsho Shinkeigaku; 2010 Nov; 50(11):1022-4. PubMed ID: 21921552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
    Janssens J; Kleinberger G; Wils H; Van Broeckhoven C
    Biochem Soc Trans; 2011 Aug; 39(4):954-9. PubMed ID: 21787329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.
    Lim L; Wei Y; Lu Y; Song J
    PLoS Biol; 2016 Jan; 14(1):e1002338. PubMed ID: 26735904
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Folding of the RNA recognition motif (RRM) domains of the amyotrophic lateral sclerosis (ALS)-linked protein TDP-43 reveals an intermediate state.
    Mackness BC; Tran MT; McClain SP; Matthews CR; Zitzewitz JA
    J Biol Chem; 2014 Mar; 289(12):8264-76. PubMed ID: 24497641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Clinical and pathological spectrum of TDP-43 associated ALS].
    Onodera O; Yokoseki A; Tan CF; Ishihara T; Nishiira Y; Toyoshima Y; Kakita A; Nishizawa M; Takahashi H
    Rinsho Shinkeigaku; 2010 Nov; 50(11):940-2. PubMed ID: 21921519
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
    Collins M; Riascos D; Kovalik T; An J; Krupa K; Krupa K; Hood BL; Conrads TP; Renton AE; Traynor BJ; Bowser R
    Acta Neuropathol; 2012 Nov; 124(5):717-32. PubMed ID: 22993125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
    Sreedharan J; Blair IP; Tripathi VB; Hu X; Vance C; Rogelj B; Ackerley S; Durnall JC; Williams KL; Buratti E; Baralle F; de Belleroche J; Mitchell JD; Leigh PN; Al-Chalabi A; Miller CC; Nicholson G; Shaw CE
    Science; 2008 Mar; 319(5870):1668-72. PubMed ID: 18309045
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpression of ALS-associated p.M337V human TDP-43 in mice worsens disease features compared to wild-type human TDP-43 mice.
    Janssens J; Wils H; Kleinberger G; Joris G; Cuijt I; Ceuterick-de Groote C; Van Broeckhoven C; Kumar-Singh S
    Mol Neurobiol; 2013 Aug; 48(1):22-35. PubMed ID: 23475610
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ALS/FTLD-linked TDP-43 regulates neurite morphology and cell survival in differentiated neurons.
    Han JH; Yu TH; Ryu HH; Jun MH; Ban BK; Jang DJ; Lee JA
    Exp Cell Res; 2013 Aug; 319(13):1998-2005. PubMed ID: 23742895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amyotrophic lateral sclerosis mutant TDP-43 may cause synaptic dysfunction through altered dendritic spine function.
    Jiang T; Handley E; Brizuela M; Dawkins E; Lewis KEA; Clark RM; Dickson TC; Blizzard CA
    Dis Model Mech; 2019 May; 12(5):. PubMed ID: 31036551
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.