These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

62 related articles for article (PubMed ID: 21667041)

  • 1. Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.
    Marcuzzi A; Piscianz E; Girardelli M; Crovella S; Pontillo A
    Apoptosis; 2011 Sep; 16(9):882-8. PubMed ID: 21667041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Natural isoprenoids inhibit LPS-induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes.
    Marcuzzi A; Tommasini A; Crovella S; Pontillo A
    Int Immunopharmacol; 2010 Jun; 10(6):639-42. PubMed ID: 20304105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes.
    Massonnet B; Normand S; Moschitz R; Delwail A; Favot L; Garcia M; Bourmeyster N; Cuisset L; Grateau G; Morel F; Silvain C; Lecron JC
    Eur Cytokine Netw; 2009 Sep; 20(3):112-20. PubMed ID: 19825520
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.
    Kuijk LM; Mandey SH; Schellens I; Waterham HR; Rijkers GT; Coffer PJ; Frenkel J
    Mol Immunol; 2008 Apr; 45(8):2158-65. PubMed ID: 18242710
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A role for geranylgeranylation in interleukin-1beta secretion.
    Mandey SH; Kuijk LM; Frenkel J; Waterham HR
    Arthritis Rheum; 2006 Nov; 54(11):3690-5. PubMed ID: 17075828
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of interleukin-1beta-converting enzyme by nigericin is independent of apoptosis.
    Watanabe N; Kawaguchi M; Kobayashi Y
    Cytokine; 1998 Sep; 10(9):645-53. PubMed ID: 9770325
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histidine decarboxylase-stimulating and inflammatory effects of alendronate in mice: involvement of mevalonate pathway, TNFalpha, macrophages, and T-cells.
    Deng X; Yu Z; Funayama H; Yamaguchi K; Sasano T; Sugawara S; Endo Y
    Int Immunopharmacol; 2007 Feb; 7(2):152-61. PubMed ID: 17178381
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alendronate, a double-edged sword acting in the mevalonate pathway.
    Tricarico PM; Girardelli M; Kleiner G; Knowles A; Valencic E; Crovella S; Marcuzzi A
    Mol Med Rep; 2015 Sep; 12(3):4238-4242. PubMed ID: 26096667
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Geraniol rescues inflammation in cellular and animal models of mevalonate kinase deficiency.
    Marcuzzi A; Crovella S; Pontillo A
    In Vivo; 2011; 25(1):87-92. PubMed ID: 21282739
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Specific increase in caspase-1 activity and secretion of IL-1 family cytokines: a putative link between mevalonate kinase deficiency and inflammation.
    Normand S; Massonnet B; Delwail A; Favot L; Cuisset L; Grateau G; Morel F; Silvain C; Lecron JC
    Eur Cytokine Netw; 2009 Sep; 20(3):101-7. PubMed ID: 19825518
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.
    De Leo L; Marcuzzi A; Decorti G; Tommasini A; Crovella S; Pontillo A
    Pharmacol Res; 2010 Jun; 61(6):506-10. PubMed ID: 20206266
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells.
    Hurst J; Prinz N; Lorenz M; Bauer S; Chapman J; Lackner KJ; von Landenberg P
    Immunobiology; 2009; 214(8):683-91. PubMed ID: 19249118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.
    Marcuzzi A; De Leo L; Decorti G; Crovella S; Tommasini A; Pontillo A
    Pediatr Res; 2011 Jul; 70(1):78-82. PubMed ID: 21430599
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin.
    Hentze H; Lin XY; Choi MS; Porter AG
    Cell Death Differ; 2003 Sep; 10(9):956-68. PubMed ID: 12934070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.
    Shikama Y; Nagai Y; Okada S; Oizumi T; Shimauchi H; Sugawara S; Endo Y
    Toxicol Lett; 2010 Nov; 199(2):123-8. PubMed ID: 20804833
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucocorticoids induce apoptosis in human monocytes: potential role of IL-1 beta.
    Schmidt M; Pauels HG; Lügering N; Lügering A; Domschke W; Kucharzik T
    J Immunol; 1999 Sep; 163(6):3484-90. PubMed ID: 10477621
    [TBL] [Abstract][Full Text] [Related]  

  • 17. STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria.
    Samavati L; Rastogi R; Du W; Hüttemann M; Fite A; Franchi L
    Mol Immunol; 2009 May; 46(8-9):1867-77. PubMed ID: 19299019
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency.
    Pontillo A; Paoluzzi E; Crovella S
    Eur J Hum Genet; 2010 Jul; 18(7):844-7. PubMed ID: 20179743
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation.
    Clark AK; D'Aquisto F; Gentry C; Marchand F; McMahon SB; Malcangio M
    J Neurochem; 2006 Nov; 99(3):868-80. PubMed ID: 16942597
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential dependence of the ingestion of necrotic cells and TNF-alpha / IL-1beta production by murine macrophages on lipid rafts.
    Acosta-Pérez G; Maximina Bertha Moreno-Altamirano M; Rodríguez-Luna G; Javier Sánchez-Garcia F
    Scand J Immunol; 2008 Oct; 68(4):423-9. PubMed ID: 18782272
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.