BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 21669874)

  • 1. SKAP1 protein PH domain determines RapL membrane localization and Rap1 protein complex formation for T cell receptor (TCR) activation of LFA-1.
    Raab M; Smith X; Matthess Y; Strebhardt K; Rudd CE
    J Biol Chem; 2011 Aug; 286(34):29663-70. PubMed ID: 21669874
    [TBL] [Abstract][Full Text] [Related]  

  • 2. T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes.
    Raab M; Wang H; Lu Y; Smith X; Wu Z; Strebhardt K; Ladbury JE; Rudd CE
    Immunity; 2010 Apr; 32(4):541-56. PubMed ID: 20346707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.
    Patzak IM; Königsberger S; Suzuki A; Mak TW; Kiefer F
    Eur J Immunol; 2010 Nov; 40(11):3220-5. PubMed ID: 20957749
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion.
    Xiong Y; Ye C; Yang N; Li M; Liu H
    J Immunol; 2017 Dec; 199(12):4142-4154. PubMed ID: 29127148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration.
    Miertzschke M; Stanley P; Bunney TD; Rodrigues-Lima F; Hogg N; Katan M
    J Biol Chem; 2007 Oct; 282(42):30629-42. PubMed ID: 17716979
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region.
    Raab M; Strebhardt K; Rudd CE
    BMC Res Notes; 2018 Dec; 11(1):869. PubMed ID: 30522503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.
    Katagiri K; Maeda A; Shimonaka M; Kinashi T
    Nat Immunol; 2003 Aug; 4(8):741-8. PubMed ID: 12845325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules.
    Kliche S; Worbs T; Wang X; Degen J; Patzak I; Meineke B; Togni M; Moser M; Reinhold A; Kiefer F; Freund C; Förster R; Schraven B
    Blood; 2012 Jan; 119(3):777-85. PubMed ID: 22117043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.
    Raab M; Lu Y; Kohler K; Smith X; Strebhardt K; Rudd CE
    Nat Commun; 2017 Jul; 8():16001. PubMed ID: 28699640
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.
    Lim D; Lu Y; Rudd CE
    Immunol Lett; 2016 Apr; 172():40-6. PubMed ID: 26905930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes.
    Witte A; Meineke B; Sticht J; Philipsen L; Kuropka B; Müller AJ; Freund C; Schraven B; Kliche S
    Mol Cell Biol; 2017 Apr; 37(7):. PubMed ID: 28052935
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.
    Côte M; Fos C; Canonigo-Balancio AJ; Ley K; Bécart S; Altman A
    J Cell Sci; 2015 Dec; 128(23):4341-52. PubMed ID: 26483383
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.
    Mor A; Dustin ML; Philips MR
    Immunol Rev; 2007 Aug; 218():114-25. PubMed ID: 17624948
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1.
    Katagiri K; Shimonaka M; Kinashi T
    J Biol Chem; 2004 Mar; 279(12):11875-81. PubMed ID: 14702343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells.
    Johansen KH; Golec DP; Huang B; Park C; Thomsen JH; Preite S; Cannons JL; Garçon F; Schrom EC; Courrèges CJF; Veres TZ; Harrison J; Nus M; Phelan JD; Bergmeier W; Kehrl JH; Okkenhaug K; Schwartzberg PL
    Sci Signal; 2022 Jul; 15(743):eabl9169. PubMed ID: 35857633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells.
    Feigelson SW; Grabovsky V; Manevich-Mendelson E; Pasvolsky R; Shulman Z; Shinder V; Klein E; Etzioni A; Aker M; Alon R
    Blood; 2011 Jun; 117(26):7042-52. PubMed ID: 21536861
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coupling of the TCR to integrin activation by Slap-130/Fyb.
    Peterson EJ; Woods ML; Dmowski SA; Derimanov G; Jordan MS; Wu JN; Myung PS; Liu QH; Pribila JT; Freedman BD; Shimizu Y; Koretzky GA
    Science; 2001 Sep; 293(5538):2263-5. PubMed ID: 11567141
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation.
    Ménasché G; Kliche S; Chen EJ; Stradal TE; Schraven B; Koretzky G
    Mol Cell Biol; 2007 Jun; 27(11):4070-81. PubMed ID: 17403904
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in RAPL-dependent and -independent manners.
    Ebisuno Y; Katagiri K; Katakai T; Ueda Y; Nemoto T; Inada H; Nabekura J; Okada T; Kannagi R; Tanaka T; Miyasaka M; Hogg N; Kinashi T
    Blood; 2010 Jan; 115(4):804-14. PubMed ID: 19965628
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PKC-theta selectively controls the adhesion-stimulating molecule Rap1.
    Letschka T; Kollmann V; Pfeifhofer-Obermair C; Lutz-Nicoladoni C; Obermair GJ; Fresser F; Leitges M; Hermann-Kleiter N; Kaminski S; Baier G
    Blood; 2008 Dec; 112(12):4617-27. PubMed ID: 18796635
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.