233 related articles for article (PubMed ID: 21670543)
1. A 1H NMR-based metabolomics approach for mechanistic insight into acetaminophen-induced hepatotoxicity.
Fukuhara K; Ohno A; Ando Y; Yamoto T; Okuda H
Drug Metab Pharmacokinet; 2011; 26(4):399-406. PubMed ID: 21670543
[TBL] [Abstract][Full Text] [Related]
2. Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity.
Cheng J; Ma X; Krausz KW; Idle JR; Gonzalez FJ
Drug Metab Dispos; 2009 Aug; 37(8):1611-21. PubMed ID: 19460945
[TBL] [Abstract][Full Text] [Related]
3. Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: application to acetaminophen injury.
Prot JM; Bunescu A; Elena-Herrmann B; Aninat C; Snouber LC; Griscom L; Razan F; Bois FY; Legallais C; Brochot C; Corlu A; Dumas ME; Leclerc E
Toxicol Appl Pharmacol; 2012 Mar; 259(3):270-80. PubMed ID: 22230336
[TBL] [Abstract][Full Text] [Related]
4. Metabolic phenotyping applied to pre-clinical and clinical studies of acetaminophen metabolism and hepatotoxicity.
Coen M
Drug Metab Rev; 2015 Feb; 47(1):29-44. PubMed ID: 25533740
[TBL] [Abstract][Full Text] [Related]
5. Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver.
Zhao P; Kalhorn TF; Slattery JT
Hepatology; 2002 Aug; 36(2):326-35. PubMed ID: 12143040
[TBL] [Abstract][Full Text] [Related]
6. Combination of electrochemistry and nuclear magnetic resonance spectroscopy for metabolism studies.
Simon H; Melles D; Jacquoilleot S; Sanderson P; Zazzeroni R; Karst U
Anal Chem; 2012 Oct; 84(20):8777-82. PubMed ID: 22971210
[TBL] [Abstract][Full Text] [Related]
7. Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.
Kyriakides M; Maitre L; Stamper BD; Mohar I; Kavanagh TJ; Foster J; Wilson ID; Holmes E; Nelson SD; Coen M
Arch Toxicol; 2016 Dec; 90(12):3073-3085. PubMed ID: 26746206
[TBL] [Abstract][Full Text] [Related]
8. Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Kondo K; Yamada N; Suzuki Y; Toyoda K; Hashimoto T; Takahashi A; Kobayashi A; Shoda T; Kuno H; Sugai S
J Toxicol Sci; 2012; 37(5):911-29. PubMed ID: 23038001
[TBL] [Abstract][Full Text] [Related]
9. Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice.
Tonge RP; Kelly EJ; Bruschi SA; Kalhorn T; Eaton DL; Nebert DW; Nelson SD
Toxicol Appl Pharmacol; 1998 Nov; 153(1):102-8. PubMed ID: 9875304
[TBL] [Abstract][Full Text] [Related]
10. Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.
Lin MC; Wang EJ; Patten C; Lee MJ; Xiao F; Reuhl KR; Yang CS
J Biochem Toxicol; 1996; 11(1):11-20. PubMed ID: 8806047
[TBL] [Abstract][Full Text] [Related]
11. Autophagy and acetaminophen-induced hepatotoxicity.
Shan S; Shen Z; Song F
Arch Toxicol; 2018 Jul; 92(7):2153-2161. PubMed ID: 29876591
[TBL] [Abstract][Full Text] [Related]
12. Acetaminophen reactive intermediates target hepatic thioredoxin reductase.
Jan YH; Heck DE; Dragomir AC; Gardner CR; Laskin DL; Laskin JD
Chem Res Toxicol; 2014 May; 27(5):882-94. PubMed ID: 24661219
[TBL] [Abstract][Full Text] [Related]
13. Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine.
Tan SC; New LS; Chan EC
Toxicol Lett; 2008 Aug; 180(3):174-81. PubMed ID: 18588957
[TBL] [Abstract][Full Text] [Related]
14. Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics.
Sun J; Schnackenberg LK; Beger RD
Drug Metab Lett; 2009 Aug; 3(3):130-6. PubMed ID: 19702550
[TBL] [Abstract][Full Text] [Related]
15. LC-MS analyses of N-acetyl-p-benzoquinone imine-adducts of glutathione, cysteine, N-acetylcysteine, and albumin in a plasma sample: A case study from a patient with a rare acetaminophen-induced acute swelling rash.
Ozawa M; Kubo T; Lee SH; Oe T
J Toxicol Sci; 2019; 44(8):559-563. PubMed ID: 31378767
[TBL] [Abstract][Full Text] [Related]
16. Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice.
Lu Y; Sun J; Petrova K; Yang X; Greenhaw J; Salminen WF; Beger RD; Schnackenberg LK
Food Chem Toxicol; 2013 Dec; 62():707-21. PubMed ID: 24080264
[TBL] [Abstract][Full Text] [Related]
17. Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease.
Michaut A; Moreau C; Robin MA; Fromenty B
Liver Int; 2014 Aug; 34(7):e171-9. PubMed ID: 24575957
[TBL] [Abstract][Full Text] [Related]
18. Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.
Wang EJ; Li Y; Lin M; Chen L; Stein AP; Reuhl KR; Yang CS
Toxicol Appl Pharmacol; 1996 Jan; 136(1):146-54. PubMed ID: 8560468
[TBL] [Abstract][Full Text] [Related]
19. Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury.
Shayiq RM; Roberts DW; Rothstein K; Snawder JE; Benson W; Ma X; Black M
Hepatology; 1999 Feb; 29(2):451-63. PubMed ID: 9918922
[TBL] [Abstract][Full Text] [Related]
20. Temporal variation in hepatotoxicity and metabolism of acetaminophen in mice.
Kim YC; Lee SJ
Toxicology; 1998 Jun; 128(1):53-61. PubMed ID: 9704905
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
